Featured Research

from universities, journals, and other organizations

Study Finds Bupropion May Be Effective Smoking Cessation Aid For Women

Date:
May 4, 2004
Source:
NIH/National Institute On Drug Abuse
Summary:
NIDA-funded scientists have found that the antidepressant medication bupropion may help women who are light smokers maintain abstinence at rates similar to those of men.

Research has indicated that women smokers have more difficulty quitting and maintaining abstinence from cigarettes than men. Several factors may contribute to gender differences in smoking cessation outcomes, including depression and fears of gaining weight. NIDA-funded scientists have found that the antidepressant medication bupropion may help women who are light smokers maintain abstinence at rates similar to those of men.

For the study, the researchers recruited 314 women and 241 men who smoked at least 10 cigarettes per day. Participants were assigned to receive bupropion, commonly known as Zyban or Wellbutrin, accompanied by behavioral counseling or counseling only. Behavioral counseling was designed to help participants reduce smoking, learn to cope with stress and situations that trigger their desire to smoke, and prevent relapse. Two weeks after participants began taking bupropion, or on the day of the third counseling session, they were instructed to stop smoking. Abstinence from smoking was evaluated at 8 weeks (end of treatment) and 6 months after the quit date, and was verified by saliva analysis for the presence of cotinine, an indicator of smoking.

At the end of treatment, 51 percent of the men and 40 percent of the women had remained abstinent from smoking. At the 6-month follow-up, about 32 percent of the men and 22 percent of the women were abstinent from smoking. The researchers found that, overall, women receiving both bupropion and behavioral counseling had abstinence rates similar to those of the men. However, women receiving behavioral counseling alone were more likely to relapse to smoking than the men. At the end of treatment, about 55 percent of the women receiving bupropion were abstinent from smoking compared with 35 percent of those receiving behavioral counseling alone. Women who received bupropion and smoked fewer than 20 cigarettes per day were twice as likely to remain abstinent than those receiving behavioral counseling alone. However, bupropion had little effect on the abstinence rates of women who smoked more than 20 cigarettes per day. For men, however, bupropion was more effective for heavy smokers than light smokers.

These findings indicate that bupropion may be an effective treatment for women who are light smokers. Identifying gender-specific smoking cessation factors will aid in the development of more effective treatment programs targeted to women.

This study was published in the February 2004 issue of Nicotine and Tobacco Research by lead investigator Bradley Collins at the University of Pennsylvania.


Story Source:

The above story is based on materials provided by NIH/National Institute On Drug Abuse. Note: Materials may be edited for content and length.


Cite This Page:

NIH/National Institute On Drug Abuse. "Study Finds Bupropion May Be Effective Smoking Cessation Aid For Women." ScienceDaily. ScienceDaily, 4 May 2004. <www.sciencedaily.com/releases/2004/05/040504062919.htm>.
NIH/National Institute On Drug Abuse. (2004, May 4). Study Finds Bupropion May Be Effective Smoking Cessation Aid For Women. ScienceDaily. Retrieved April 17, 2014 from www.sciencedaily.com/releases/2004/05/040504062919.htm
NIH/National Institute On Drug Abuse. "Study Finds Bupropion May Be Effective Smoking Cessation Aid For Women." ScienceDaily. www.sciencedaily.com/releases/2004/05/040504062919.htm (accessed April 17, 2014).

Share This



More Mind & Brain News

Thursday, April 17, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Are School Dress Codes Too Strict?

Are School Dress Codes Too Strict?

AP (Apr. 16, 2014) Pushing the limits on style and self-expression is a rite of passage for teens and even younger kids. How far should schools go with their dress codes? The courts have sided with schools in an era when school safety is paramount. (April 16) Video provided by AP
Powered by NewsLook.com
Could Even Casual Marijuana Use Alter Your Brain?

Could Even Casual Marijuana Use Alter Your Brain?

Newsy (Apr. 16, 2014) A new study conducted by researchers at Northwestern and Harvard suggests even casual marijuana use can alter your brain. Video provided by Newsy
Powered by NewsLook.com
Couples Who Sleep Less Than An Inch Apart Might Be Happiest

Couples Who Sleep Less Than An Inch Apart Might Be Happiest

Newsy (Apr. 16, 2014) A new study by British researchers suggests couples' sleeping positions might reflect their happiness. Video provided by Newsy
Powered by NewsLook.com
Cognitive Function: Is It All Downhill From Age 24?

Cognitive Function: Is It All Downhill From Age 24?

Newsy (Apr. 15, 2014) A new study out of Canada says cognitive motor performance begins deteriorating around age 24. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins