Featured Research

from universities, journals, and other organizations

Bone Marrow Fat May Indicate Bone Weakening

Date:
December 15, 2004
Source:
American Roentgen Ray Society
Summary:
Measuring bone marrow fat (BMF) along with bone mineral density (BMD) can better predict weakening of bones than either test done alone, a new study indicates. BMD measurement with DEXA is presently the most commonly used parameter for determining bone weakening. Researchers have long questioned whether there may be other measurable bone components that influence mechanical stability of bone.

Measuring bone marrow fat (BMF) along with bone mineral density (BMD) can better predict weakening of bones than either test done alone, a new study indicates. BMD measurement with DEXA is presently the most commonly used parameter for determining bone weakening. Researchers have long questioned whether there may be other measurable bone components that influence mechanical stability of bone.

The study, conducted by researchers at Georgetown University Hospital in Washington DC, showed that increased BMF is an independent marker of bone weakening. MR spectroscopy was used to gauge BMF non-invasively. MR spectroscopy is a relatively new technique that can be done in conjunction with a spine MRI. This is a pilot study that included 26 patients who underwent both DEXA and MR spectroscopy of the lumbar spine, said Dieter Schellinger, MD, author of the study. Fifteen had normal appearing spine vertebra and eleven showed signs of bone weakening.

When the results of DEXA and MR spectroscopy tests were compared, the ratio of BMF to BMD was "a significant diagnostic indicator of bone weakening," said Dr. Schellinger. The ratio was higher in healthy people and lower in those with signs of bone weakening, he said.

Dr. Schellinger said that other researchers have previously suspected that increased bone fat content represent a bone risk factor. However, before MR spectroscopy, doctors needed to examine bone fat by operatively removing bone samples from patients. A non-invasive method such as MR spectroscopy opens new diagnostic opportunities, he said.

If these results are confirmed by larger studies, increased fat accumulation in bone could be treated with new medications, in an effort to avoid further bone weakening, Dr. Schellinger said.

###

The study appears in the December 2004 issue of the American Journal of Roentgenology.


Story Source:

The above story is based on materials provided by American Roentgen Ray Society. Note: Materials may be edited for content and length.


Cite This Page:

American Roentgen Ray Society. "Bone Marrow Fat May Indicate Bone Weakening." ScienceDaily. ScienceDaily, 15 December 2004. <www.sciencedaily.com/releases/2004/12/041208084143.htm>.
American Roentgen Ray Society. (2004, December 15). Bone Marrow Fat May Indicate Bone Weakening. ScienceDaily. Retrieved September 17, 2014 from www.sciencedaily.com/releases/2004/12/041208084143.htm
American Roentgen Ray Society. "Bone Marrow Fat May Indicate Bone Weakening." ScienceDaily. www.sciencedaily.com/releases/2004/12/041208084143.htm (accessed September 17, 2014).

Share This



More Health & Medicine News

Wednesday, September 17, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Obesity Rates Steady Even As Americans' Waistlines Expand

Obesity Rates Steady Even As Americans' Waistlines Expand

Newsy (Sep. 17, 2014) Researchers are puzzled as to why obesity rates remain relatively stable as average waistlines continue to expand. Video provided by Newsy
Powered by NewsLook.com
President To Send 3,000 Military Personnel To Fight Ebola

President To Send 3,000 Military Personnel To Fight Ebola

Newsy (Sep. 16, 2014) President Obama is expected to send 3,000 troops to West Africa as part of the effort to contain Ebola's spread. Video provided by Newsy
Powered by NewsLook.com
Obama Orders Military Response to Ebola

Obama Orders Military Response to Ebola

AP (Sep. 16, 2014) Calling the Ebola outbreak in West Africa a potential threat to global security, President Barack Obama is ordering 3,000 U.S. military personnel to the stricken region amid worries that the outbreak is spiraling out of control. (Sept. 16) Video provided by AP
Powered by NewsLook.com
UN: 20,000 Could Be Infected With Ebola by Year End

UN: 20,000 Could Be Infected With Ebola by Year End

AFP (Sep. 16, 2014) Nearly $1.0 billion dollars is needed to fight the Ebola outbreak raging in west Africa, the United Nations say, warning that 20,000 could be infected by year end. Duration: 00:40 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins