Featured Research

from universities, journals, and other organizations

Finding Lymph Node Metastases In Cancer

Date:
January 16, 2005
Source:
Public Library Of Science
Summary:
In a paper published in the premier open-access medical journal PloS Medicine this month, Mukesh Harisinghani and Ralph Weissleder describe a technique that could begin to make the staging of cancer both more accurate and less invasive.

3-D image of lymph node after automated analysis. Courtesy of Ralph Weissleder.

In a paper published in the premier open-access medical journal PloS Medicine this month, Mukesh Harisinghani and Ralph Weissleder describe a technique that could begin to make the staging of cancer both more accurate and less invasive. Correct staging of cancers is one of the most important parts of the work up of patients for both prediction of outcome and determination of the most appropriate treatment. But at the moment many staging techniques either require surgery or are not sufficiently accurate.

The authors used extremely small magnetic particles (called nanoparticles) that homed to lymph nodes, and then tracked the nodes using MRI. In a study in 70 patients with a range of different cancers--36 that they developed the technique on and 34 that they tested the results on--the authors were able to see different patterns for normal and malignant nodes. It was then possible to design a computer program that could recognize metastases. And then the program was able to produce a 3-D reconstruction of the lymph nodes which could possibly be used by oncologists and surgeons to provide optimal treatment. "This method of cancer staging provides unprecedented accuracy and will spare unnecessary surgery" says Dr. Weissleder.

###

Citation: Harisinghani M, Weissleder R (2004) Sensitive, noninvasive detection of lymph node metastases. PLoS Med 1 (3): e66.


Story Source:

The above story is based on materials provided by Public Library Of Science. Note: Materials may be edited for content and length.


Cite This Page:

Public Library Of Science. "Finding Lymph Node Metastases In Cancer." ScienceDaily. ScienceDaily, 16 January 2005. <www.sciencedaily.com/releases/2005/01/050111171658.htm>.
Public Library Of Science. (2005, January 16). Finding Lymph Node Metastases In Cancer. ScienceDaily. Retrieved September 20, 2014 from www.sciencedaily.com/releases/2005/01/050111171658.htm
Public Library Of Science. "Finding Lymph Node Metastases In Cancer." ScienceDaily. www.sciencedaily.com/releases/2005/01/050111171658.htm (accessed September 20, 2014).

Share This



More Health & Medicine News

Saturday, September 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Could Grief Affect The Immune Systems Of Senior Citizens?

Could Grief Affect The Immune Systems Of Senior Citizens?

Newsy (Sep. 19, 2014) The study found elderly people are much more likely to become susceptible to infection than younger adults going though a similar situation. Video provided by Newsy
Powered by NewsLook.com
Jury Delivers Verdict in Salmonella Trial

Jury Delivers Verdict in Salmonella Trial

AP (Sep. 19, 2014) A federal jury has convicted three people in connection with an outbreak of salmonella poisoning five years ago that sickened hundreds of people and was linked to a number of deaths. (Sept. 19) Video provided by AP
Powered by NewsLook.com
How The 'Angelina Jolie Effect' Increased Cancer Screenings

How The 'Angelina Jolie Effect' Increased Cancer Screenings

Newsy (Sep. 19, 2014) Angelina's Jolie's decision to undergo a preventative mastectomy in 2013 inspired many women to seek early screenings for the disease. Video provided by Newsy
Powered by NewsLook.com
The Cost of Ebola

The Cost of Ebola

Reuters - Business Video Online (Sep. 18, 2014) As Sierra Leone prepares for a three-day "lockdown" in its latest bid to stem the spread of Ebola, Ciara Lee looks at the financial implications of fighting the largest ever outbreak of the disease. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins