Featured Research

from universities, journals, and other organizations

Diabetes A Bigger Heart Disease Risk For Women Than For Men

Date:
February 26, 2005
Source:
American Heart Association
Summary:
Women with diabetes have a significantly greater risk of dying from coronary heart disease (CHD) than men with diabetes, researchers reported at the Second International Conference on Women, Heart Disease and Stroke.

ORLANDO, Feb. 18 – Women with diabetes have a significantly greater risk of dying from coronary heart disease (CHD) than men with diabetes, researchers reported today at the Second International Conference on Women, Heart Disease and Stroke.

Related Articles


Diabetes is a well-established CHD risk factor known to double a person's chance of dying from heart disease. There has been much debate, but no large studies of whether diabetes carries different heart risks for women than for men, said Mark Woodward, Ph.D., professor of biostatistics at The George Institute for International Health at the University of Sydney, Australia.

Using data on more than 450,000 people, which included participants in the Asia Pacific Cohort Studies Collaboration, researchers found that men with diabetes had about 90 percent higher risk of dying from CHD as men without diabetes. Women with diabetes had more than two and a half times the risk of women without diabetes. That translates to a greater than 50 percent excess relative risk for women than for men, he said.

The data came from two previous meta-analyses of 16 studies and a collaborative overview of 44 studies in nine countries in the Asia-Pacific Region (China, Japan, South Korea, Taiwan, Hong Kong, Singapore, Thailand, New Zealand and Australia).

About 5 percent of all the participants had diabetes. Diabetes was defined according to self-reported history with or without fasting glucose evidence as an alternative. The researchers were able to adjust for age, systolic blood pressure, total cholesterol and cigarette smoking in most of the data sets, he said.

Perhaps better monitoring and control of blood glucose levels in women with diabetes would reduce their CHD risk compared with men with diabetes, Woodward said.

"There is some evidence to suggest that people with diabetes benefit from treatment with aspirin, cholesterol-lowering drugs and blood pressure-lowering agents," he said.

This meta-analysis has similar drawbacks to most overviews including the possibility of publication bias (in this case the exclusion of studies that did not report sex-specific results), misdiagnosis of diabetes, lack of information on an individuals' medical treatment, no information on menopause status or on whether subjects had Type 1 diabetes, due to the body's inability to produce insulin, or Type 2 diabetes, initially caused by the inability to use the insulin produced. Data from randomized trials of individuals with diabetes would clarify these issues.

Besides continuing to seek data on the sex-specific relative risk for CHD related to diabetes, researchers at the George Institute are leading a large scale randomized trial Action in Diabetes and Vascular Disease: Preterax and Diamicron MR Controlled Evaluation (ADVANCE) on 11,140 people. They are trying to ascertain whether more intensive glucose control combined with blood pressure lowering reduces cardiovascular mortality in people with Type 2 diabetes. The trial, which will follow participants for 4 ½ years on average, will end in 2006.

###

The conference is jointly sponsored by the American Heart Association, the Centers for Disease Control and Prevention, the American College of Cardiology Foundation, the World Heart Federation, the National Heart, Lung, and Blood Institute, and the Heart and Stroke Foundation of Canada.

This abstract was published in the February 2005 issue of Circulation: Journal of the American Heart Association.

Co-authors are: Federica Barzi and Rachel Huxley.

Statements and conclusions of study authors that are published in the American Heart Association scientific journals are solely those of the study authors and do not necessarily reflect association policy or position. The American Heart Association makes no representation or warranty as to their accuracy or reliability.


Story Source:

The above story is based on materials provided by American Heart Association. Note: Materials may be edited for content and length.


Cite This Page:

American Heart Association. "Diabetes A Bigger Heart Disease Risk For Women Than For Men." ScienceDaily. ScienceDaily, 26 February 2005. <www.sciencedaily.com/releases/2005/02/050223143424.htm>.
American Heart Association. (2005, February 26). Diabetes A Bigger Heart Disease Risk For Women Than For Men. ScienceDaily. Retrieved November 27, 2014 from www.sciencedaily.com/releases/2005/02/050223143424.htm
American Heart Association. "Diabetes A Bigger Heart Disease Risk For Women Than For Men." ScienceDaily. www.sciencedaily.com/releases/2005/02/050223143424.htm (accessed November 27, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, November 27, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Leaves Orphans Alone in Sierra Leone

Ebola Leaves Orphans Alone in Sierra Leone

AFP (Nov. 27, 2014) — The Ebola epidemic sweeping Sierra Leone is having a profound effect on the country's children, many of whom have been left without any family members to support them. Duration: 01:02 Video provided by AFP
Powered by NewsLook.com
Experimental Ebola Vaccine Shows Promise In Human Trial

Experimental Ebola Vaccine Shows Promise In Human Trial

Newsy (Nov. 27, 2014) — A recent test of a prototype Ebola vaccine generated an immune response to the disease in subjects. Video provided by Newsy
Powered by NewsLook.com
Pet Dogs to Be Used in Anti-Ageing Trial

Pet Dogs to Be Used in Anti-Ageing Trial

Reuters - Innovations Video Online (Nov. 26, 2014) — Researchers in the United States are preparing to discover whether a drug commonly used in human organ transplants can extend the lifespan and health quality of pet dogs. Video provided by Reuters
Powered by NewsLook.com
Today's Prostheses Are More Capable Than Ever

Today's Prostheses Are More Capable Than Ever

Newsy (Nov. 26, 2014) — Advances in prosthetics are making replacement body parts stronger and more lifelike than they’ve ever been. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins