Featured Research

from universities, journals, and other organizations

Risks Outweigh Benefits Of Shark Cartilage As Anti-cancer Treatment

Date:
May 23, 2005
Source:
John Wiley & Sons, Inc.
Summary:
As a treatment for advanced cancer, shark cartilage fails to benefit patients and its adverse effects lead to poor compliance. A clinical trial finds there was no difference in overall survival or quality of life between patients who received shark cartilage and those who received a placebo.

As a treatment for advanced cancer, shark cartilage fails to benefit patients and its adverse effects lead to poor compliance. A clinical trial published in the July 1, 2005 issue of CANCER, a peer-reviewed journal of the American Cancer Society, finds there was no difference in overall survival or quality of life between patients who received shark cartilage and those who received a placebo.

Some experiments have shown that some forms of shark cartilage possess a modest ability to slow the growth of new blood vessels in laboratory cell cultures and in animals, but the effects on humans are not known. Interest in shark cartilage grew after a television news magazine aired a segment in 1993 that showed patients with advanced cancer in Cuba who had gone into remission after being treated with shark cartilage. The results of the study were never published in a peer-reviewed medical journal, and the National Cancer Institute (NCI) later concluded the results of the Cuban study were "incomplete and unimpressive."

Mayo Clinic Oncologist Charles L. Loprinzi, M.D., and his colleagues in the North Central Cancer Treatment Group (NCCTG) designed and conducted a randomized, placebo-controlled, double-blind clinical trial to investigate the efficacy associated with shark cartilage as a treatment for breast and colorectal cancer.

Toxicity related to shark cartilage resulted in significant trial drop out after one month. There was no suggestion that shark cartilage caused any improvement in overall survival nor any significant improvement in quality of life. In fact, some quality of life measurements tended to worsen among patients treated with shark cartilage.

The authors conclude, "shark cartilage did not demonstrate any efficacy in patients with advanced breast or colorectal cancers."

###

Article: "Evaluation of Shark Cartilage in Patients with Advanced Cancer: A North Central Cancer Treatment Group Trial," Charles L. Loprinzi, Ralph Levitt, Debra Barton, Jeff Sloan, Pam Atherton, Denise Smith, Shaker Dakhil, Dennis Moore, Jr., James E. Krook, Kendrith M. Rowland, Jr., Miroslaw Mazurczak, Alan Berg, George Kim, CANCER; Published Online: May 23, 2005 (DOI: 10.1002/cncr.21107); Print Issue Date: July 1, 2005.


Story Source:

The above story is based on materials provided by John Wiley & Sons, Inc.. Note: Materials may be edited for content and length.


Cite This Page:

John Wiley & Sons, Inc.. "Risks Outweigh Benefits Of Shark Cartilage As Anti-cancer Treatment." ScienceDaily. ScienceDaily, 23 May 2005. <www.sciencedaily.com/releases/2005/05/050523093339.htm>.
John Wiley & Sons, Inc.. (2005, May 23). Risks Outweigh Benefits Of Shark Cartilage As Anti-cancer Treatment. ScienceDaily. Retrieved July 31, 2014 from www.sciencedaily.com/releases/2005/05/050523093339.htm
John Wiley & Sons, Inc.. "Risks Outweigh Benefits Of Shark Cartilage As Anti-cancer Treatment." ScienceDaily. www.sciencedaily.com/releases/2005/05/050523093339.htm (accessed July 31, 2014).

Share This




More Health & Medicine News

Thursday, July 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Health Insurers' Profits Slide

Health Insurers' Profits Slide

Reuters - Business Video Online (July 30, 2014) Obamacare-related costs were said to be behind the profit plunge at Wellpoint and Humana, but Wellpoint sees the new exchanges boosting its earnings for the full year. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com
Concern Grows Over Worsening Ebola Crisis

Concern Grows Over Worsening Ebola Crisis

AFP (July 30, 2014) Pan-African airline ASKY has suspended all flights to and from the capitals of Liberia and Sierra Leone amid the worsening Ebola health crisis, which has so far caused 672 deaths in Guinea, Liberia and Sierra Leone. Duration: 00:43 Video provided by AFP
Powered by NewsLook.com
At Least 20 Chikungunya Cases in New Jersey

At Least 20 Chikungunya Cases in New Jersey

AP (July 30, 2014) At least 20 New Jersey residents have tested positive for chikungunya, a mosquito-borne virus that has spread through the Caribbean. (July 30) Video provided by AP
Powered by NewsLook.com
Xtreme Eating: Your Daily Caloric Intake All On One Plate

Xtreme Eating: Your Daily Caloric Intake All On One Plate

Newsy (July 30, 2014) The Center for Science in the Public Interest released its 2014 list of single meals with whopping calorie counts. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

    Environment News

    Technology News



      Save/Print:
      Share:

      Free Subscriptions


      Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

      Get Social & Mobile


      Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

      Have Feedback?


      Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
      Mobile: iPhone Android Web
      Follow: Facebook Twitter Google+
      Subscribe: RSS Feeds Email Newsletters
      Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins