Featured Research

from universities, journals, and other organizations

Risks Outweigh Benefits Of Shark Cartilage As Anti-cancer Treatment

Date:
May 23, 2005
Source:
John Wiley & Sons, Inc.
Summary:
As a treatment for advanced cancer, shark cartilage fails to benefit patients and its adverse effects lead to poor compliance. A clinical trial finds there was no difference in overall survival or quality of life between patients who received shark cartilage and those who received a placebo.

As a treatment for advanced cancer, shark cartilage fails to benefit patients and its adverse effects lead to poor compliance. A clinical trial published in the July 1, 2005 issue of CANCER, a peer-reviewed journal of the American Cancer Society, finds there was no difference in overall survival or quality of life between patients who received shark cartilage and those who received a placebo.

Some experiments have shown that some forms of shark cartilage possess a modest ability to slow the growth of new blood vessels in laboratory cell cultures and in animals, but the effects on humans are not known. Interest in shark cartilage grew after a television news magazine aired a segment in 1993 that showed patients with advanced cancer in Cuba who had gone into remission after being treated with shark cartilage. The results of the study were never published in a peer-reviewed medical journal, and the National Cancer Institute (NCI) later concluded the results of the Cuban study were "incomplete and unimpressive."

Mayo Clinic Oncologist Charles L. Loprinzi, M.D., and his colleagues in the North Central Cancer Treatment Group (NCCTG) designed and conducted a randomized, placebo-controlled, double-blind clinical trial to investigate the efficacy associated with shark cartilage as a treatment for breast and colorectal cancer.

Toxicity related to shark cartilage resulted in significant trial drop out after one month. There was no suggestion that shark cartilage caused any improvement in overall survival nor any significant improvement in quality of life. In fact, some quality of life measurements tended to worsen among patients treated with shark cartilage.

The authors conclude, "shark cartilage did not demonstrate any efficacy in patients with advanced breast or colorectal cancers."

###

Article: "Evaluation of Shark Cartilage in Patients with Advanced Cancer: A North Central Cancer Treatment Group Trial," Charles L. Loprinzi, Ralph Levitt, Debra Barton, Jeff Sloan, Pam Atherton, Denise Smith, Shaker Dakhil, Dennis Moore, Jr., James E. Krook, Kendrith M. Rowland, Jr., Miroslaw Mazurczak, Alan Berg, George Kim, CANCER; Published Online: May 23, 2005 (DOI: 10.1002/cncr.21107); Print Issue Date: July 1, 2005.


Story Source:

The above story is based on materials provided by John Wiley & Sons, Inc.. Note: Materials may be edited for content and length.


Cite This Page:

John Wiley & Sons, Inc.. "Risks Outweigh Benefits Of Shark Cartilage As Anti-cancer Treatment." ScienceDaily. ScienceDaily, 23 May 2005. <www.sciencedaily.com/releases/2005/05/050523093339.htm>.
John Wiley & Sons, Inc.. (2005, May 23). Risks Outweigh Benefits Of Shark Cartilage As Anti-cancer Treatment. ScienceDaily. Retrieved August 30, 2014 from www.sciencedaily.com/releases/2005/05/050523093339.htm
John Wiley & Sons, Inc.. "Risks Outweigh Benefits Of Shark Cartilage As Anti-cancer Treatment." ScienceDaily. www.sciencedaily.com/releases/2005/05/050523093339.htm (accessed August 30, 2014).

Share This




More Health & Medicine News

Saturday, August 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

3 Things To Know About The Ebola Outbreak's Progression

3 Things To Know About The Ebola Outbreak's Progression

Newsy (Aug. 29, 2014) Here are three things you need to know about the deadly Ebola outbreak's progression this week. Video provided by Newsy
Powered by NewsLook.com
Killer Amoeba Found in Louisiana Water System

Killer Amoeba Found in Louisiana Water System

AP (Aug. 28, 2014) State health officials say testing has confirmed the presence of a killer amoeba in a water system serving three St. John the Baptist Parish towns. (Aug. 28) Video provided by AP
Powered by NewsLook.com
Who Could Be Burnt by WHO's E-Cigs Move?

Who Could Be Burnt by WHO's E-Cigs Move?

Reuters - Business Video Online (Aug. 28, 2014) The World Health Organisation has called for the regulation of electronic cigarettes as both tobacco and medical products. Ciara Lee looks at the impact of the move on the tobacco industry. Video provided by Reuters
Powered by NewsLook.com
CDC Director On Ebola Outbreak: 'It's Worse Than I Feared'

CDC Director On Ebola Outbreak: 'It's Worse Than I Feared'

Newsy (Aug. 28, 2014) CDC director Tom Frieden says the Ebola outbreak is even worse than he feared. But he also said there's still hope to contain it. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins