Featured Research

from universities, journals, and other organizations

Liverpool Scientist Makes Breakthrough In Pancreatic Cancer Research

Date:
June 7, 2005
Source:
University Of Liverpool
Summary:
A scientist in Liverpool has made a surprise discovery that could predict which pancreatic cancer patients are likely to do better after surgery. A paper published recently in the journal, Cancer Research, shows that pancreatic cancer patients have better prospects when levels of a specific protein are low or undetectable in the cell nucleus.

A scientist in Liverpool has made a surprise discovery that could predict which pancreatic cancer patients are likely to do better after surgery.

Related Articles


A paper published recently in the journal, Cancer Research, shows that pancreatic cancer patients have better prospects when levels of a specific protein are low or undetectable in the cell nucleus.

The protein at the centre of the discovery is called calcyclin. Its role in pancreatic cancer is unknown, but researchers believe that patients who do not produce this protein have a better outcome. The research was carried out on pancreas cells taken from local patients following surgery.

Calcyclin was found in higher amounts and more frequently in pancreatic cancer cells compared with normal pancreatic cells. Moreover, it was found that the protein was often present in the very early stages of cancer development and before the cancer had become aggressive.

Dr Eithne Costello, from the University's Department of Surgery, who led the research, said: "We do not know whether calcyclin is a marker for pancreatic cancer growth, or whether it is an actual underlying cause promoting the growth and spread of pancreatic cancer. Pancreatic cancer is particularly difficult to treat and identifying this protein for further research is an important step in understanding pancreatic cancer. We now need to determine what the role of this protein is in pancreatic cancer, and establish what its contribution to the rapid progression of this disease may be."

Dr Lesley Walker, Director of Cancer Information at Cancer Research UK said: "Our knowledge of pancreatic cancer and how it develops is still in its infancy. This research is an important first step in understanding it better. The protein calcyclin looks as though it may have an important role in this disease, and further work is needed to find out what that is."

Information on pancreatic cancer is available on Cancer Research UK's patient information website, Cancer Help UK, http://www.cancerhelp.co.uk


Story Source:

The above story is based on materials provided by University Of Liverpool. Note: Materials may be edited for content and length.


Cite This Page:

University Of Liverpool. "Liverpool Scientist Makes Breakthrough In Pancreatic Cancer Research." ScienceDaily. ScienceDaily, 7 June 2005. <www.sciencedaily.com/releases/2005/06/050607011513.htm>.
University Of Liverpool. (2005, June 7). Liverpool Scientist Makes Breakthrough In Pancreatic Cancer Research. ScienceDaily. Retrieved January 27, 2015 from www.sciencedaily.com/releases/2005/06/050607011513.htm
University Of Liverpool. "Liverpool Scientist Makes Breakthrough In Pancreatic Cancer Research." ScienceDaily. www.sciencedaily.com/releases/2005/06/050607011513.htm (accessed January 27, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Tuesday, January 27, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Shark Bite Victim Making Amazing Recovery

Shark Bite Victim Making Amazing Recovery

AP (Jan. 27, 2015) A Texas woman who lost more than five pounds of flesh to a shark in the Bahamas earlier this month could be released from a Florida hospital soon. Experts believe she was bitten by a bull shark while snorkeling. (Jan. 27) Video provided by AP
Powered by NewsLook.com
Ebola Mistakes Should Serve a Lesson Says WHO

Ebola Mistakes Should Serve a Lesson Says WHO

AFP (Jan. 25, 2015) The World Health Organization&apos;s chief on Sunday admitted the UN agency had been caught napping on Ebola, saying it should serve a lesson to avoid similar mistakes in future. Duration: 00:55 Video provided by AFP
Powered by NewsLook.com
Disneyland Measles Outbreak Spreads To 5 States

Disneyland Measles Outbreak Spreads To 5 States

Newsy (Jan. 24, 2015) Much of the Disneyland measles outbreak is being blamed on the anti-vaccination movement. The CDC encourages just about everyone get immunized. Video provided by Newsy
Powered by NewsLook.com
Growing Measles Outbreak Worries Calif. Parents

Growing Measles Outbreak Worries Calif. Parents

AP (Jan. 23, 2015) Public health officials are rushing to contain a measles outbreak that has sickened 70 people across 6 states and Mexico. The AP&apos;s Raquel Maria Dillon has more. (Jan. 23) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins