Featured Research

from universities, journals, and other organizations

Better Early Diagnosis Of Relapsed Prostate Cancer

Date:
June 14, 2005
Source:
Elhuyar Fundazioa
Summary:
Positron Emission Topography with choline demonstrates greater efficiency in the early diagnosis of relapsed prostate cancer with respect to other imaging techniques, according to a new study.

“Positron Emission Topography with choline demonstrates greater efficiency in the early diagnosis of relapsed prostate cancer with respect to other imaging techniques”, stated Dr. Macarena Rodrνguez, of the Nuclear Medicine Service at the University Hospital of the University of Navarra. She was speaking on receiving the award for the best scientific work at the XXVI National Congress of the Spanish Society for Nuclear Medicine (SEMN), held recently in Maspalomas (the Canary Islands).

The study, entitled, “Value of PET with FDG and 11C-Choline in early diagnosis of relapsed treated prostate carcinoma”, has analysed for the first time in Spain the utility of 11C-Choline for the detection of relapses in these tumours. To date, conventional FDG (F18-fluorodeoxyglucose) has been used as a radiopharmaceutical, offering good specificity but poor sensitivity in the diagnosis of relapsed prostate carcinoma. The research centred on the analysis of the role of the choline and compared it with the results using FDG.

The research, carried out with 38 patients at the Navarre University Hospital, found that 11C-Choline gives better results in diagnosing relapsed prostate cancer. Although both radiopharmaceuticals have a specificity and a predictive negative value of 100%, 11C-Choline shows a sensitivity of 65% in the detection of relapses with low PSA (prostate-specific antigen) level, compared to 28% of FDG. Thus, it is shown to be a radiopharmaceutical especially useful for the early detection of relapsed prostate carcinoma. What is needed now are more studies to enable comparison of its results in function of the treatment that primary tumours require - radiotherapy, surgery, etc.

The awarded study forms part of the thesis of Macarena Rodrνguez who is to concentrate on the value of the choline in the pre-surgical diagnosis of prostate cancer. This involves analysing the degree of capture of choline by the tumour could have a prognostic value in the illness. This work is of great importance for its immediate utility for clinical studies of carcinoma of the prostate gland.

Prostate carcinoma

Cancer of the prostate is one of the most frequent causes of death amongst males in the industrialised countries; in fact, it is the second most common tumour amongst this population. Moreover, it has very high rates of relapse - about 15-40% within ten years.

The rise of PSA after curative treatment is the most sensitive diagnostic tool for the detection of relapse, but it does not enable pin-pointing its location - thus PET with 11C-Choline may be of great help in this situation.


Story Source:

The above story is based on materials provided by Elhuyar Fundazioa. Note: Materials may be edited for content and length.


Cite This Page:

Elhuyar Fundazioa. "Better Early Diagnosis Of Relapsed Prostate Cancer." ScienceDaily. ScienceDaily, 14 June 2005. <www.sciencedaily.com/releases/2005/06/050614235318.htm>.
Elhuyar Fundazioa. (2005, June 14). Better Early Diagnosis Of Relapsed Prostate Cancer. ScienceDaily. Retrieved September 16, 2014 from www.sciencedaily.com/releases/2005/06/050614235318.htm
Elhuyar Fundazioa. "Better Early Diagnosis Of Relapsed Prostate Cancer." ScienceDaily. www.sciencedaily.com/releases/2005/06/050614235318.htm (accessed September 16, 2014).

Share This



More Health & Medicine News

Tuesday, September 16, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

EU Ministers and Experts Meet to Discuss Ebola Reponse

EU Ministers and Experts Meet to Discuss Ebola Reponse

AFP (Sep. 15, 2014) — The European Commission met on Monday to coordinate aid that the EU can offer to African countries affected by the Ebola outbreak. Duration: 00:58 Video provided by AFP
Powered by NewsLook.com
Despite The Risks, Antibiotics Still Overprescribed For Kids

Despite The Risks, Antibiotics Still Overprescribed For Kids

Newsy (Sep. 15, 2014) — A new study finds children are prescribed antibiotics twice as often as is necessary. Video provided by Newsy
Powered by NewsLook.com
FDA Eyes Skin Shocks Used at Mass. School

FDA Eyes Skin Shocks Used at Mass. School

AP (Sep. 15, 2014) — The FDA is considering whether to ban devices used by the Judge Rotenberg Educational Center in Canton, Massachusetts, the only place in the country known to use electrical skin shocks as aversive conditioning for aggressive patients. (Sept. 15) Video provided by AP
Powered by NewsLook.com
Respiratory Virus Spreads To Northeast, Now In 21 States

Respiratory Virus Spreads To Northeast, Now In 21 States

Newsy (Sep. 14, 2014) — The respiratory virus Enterovirus D68, which targets children, has spread from the Midwest to 21 states. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins