Featured Research

from universities, journals, and other organizations

Traditional Risk Factors Best Predictor Of Cardiovascular Disease Death In Kidney Patients

Date:
July 2, 2005
Source:
NIH/National Heart, Lung, and Blood Institute
Summary:
New study findings show that traditional heart disease risk factors are more strongly associated with risk of death from cardiovascular disease than newer, emerging risk factors in older people with chronic kidney disease. These results from the National Heart, Lung, and Blood Institute-funded Cardiovascular Health Study will be published in the April 13 issue of the Journal of the American Medical Association.

New study findings show that traditional heart disease risk factors are more strongly associated with risk of death from cardiovascular disease than newer, emerging risk factors in older people with chronic kidney disease. These results from the National Heart, Lung, and Blood Institute-funded Cardiovascular Health Study will be published in the April 13 issue of the Journal of the American Medical Association.

Study participants with chronic kidney disease who also had diabetes, systolic high blood pressure, or left ventricular hypertrophy, or were smokers or exhibited low physical activity had an increased risk of death from cardiovascular causes. However, for these patients, emerging risk factors such as elevated levels of C-reactive protein, fibrinogen, and the blood clotting protein factor VIIIc were not as strongly associated with greater risk of cardiovascular death.

"The message from this study is clear: to reduce heart disease and stroke deaths in older people with chronic kidney disease, we need to target and control traditional risk factors," said Teri Manolio, M.D., Ph.D., director of NHLBI's Epidemiology and Biometry Program and a study co-author. Manolio added that many proven, effective interventions are available for reducing these risk factors including adequate control of high blood glucose and high blood pressure, increasing physical activity, and stopping smoking.

Chronic kidney disease is a known, controllable risk factor for heart disease and its incidence is on the rise. An estimated 4.5 percent of adults have physiological evidence of chronic kidney disease. The rate of kidney failure in the U.S. has doubled in the past decade. Chronic kidney disease was defined in the study by an estimated glomerular filtration rate (GFR) of less than 60ml/min/1.732, a measure of how well the kidneys are filtering waste from blood. The study defined cardiovascular mortality as death from heart disease, heart failure, peripheral vascular disease, and stroke.

The Cardiovascular Health Study is a longitudinal study of traditional and emerging risk factors for death from cardiovascular diseases in over 5,800 men and women over the age of 65 in four U.S. communities: Forsyth County, NC; Sacramento County, CA; Washington County, MD; and Pittsburgh, PA. Participants were followed for an average of 8.6 years.

###

For more information about chronic kidney disease, visit the National Institute of Diabetes and Digestive and Kidney Diseases at www.nkdep.nih.gov

NHLBI is part of the National Institutes of Health (NIH), the Federal Government's primary agency for biomedical and behavioral research. NIH is a component of the U.S. Department of Health and Human Services. Additional information about cardiovascular disease and NHLBI-supported research and educational programs are available online at the NHLBI website, www.nhlbi.nih.gov.


Story Source:

The above story is based on materials provided by NIH/National Heart, Lung, and Blood Institute. Note: Materials may be edited for content and length.


Cite This Page:

NIH/National Heart, Lung, and Blood Institute. "Traditional Risk Factors Best Predictor Of Cardiovascular Disease Death In Kidney Patients." ScienceDaily. ScienceDaily, 2 July 2005. <www.sciencedaily.com/releases/2005/07/050701213301.htm>.
NIH/National Heart, Lung, and Blood Institute. (2005, July 2). Traditional Risk Factors Best Predictor Of Cardiovascular Disease Death In Kidney Patients. ScienceDaily. Retrieved July 25, 2014 from www.sciencedaily.com/releases/2005/07/050701213301.htm
NIH/National Heart, Lung, and Blood Institute. "Traditional Risk Factors Best Predictor Of Cardiovascular Disease Death In Kidney Patients." ScienceDaily. www.sciencedaily.com/releases/2005/07/050701213301.htm (accessed July 25, 2014).

Share This




More Health & Medicine News

Friday, July 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

New Painkiller Designed To Discourage Abuse: Will It Work?

New Painkiller Designed To Discourage Abuse: Will It Work?

Newsy (July 24, 2014) The FDA approved Targiniq ER on Wednesday, a painkiller designed to keep users from abusing it. Like any new medication, however, it has doubters. Video provided by Newsy
Powered by NewsLook.com
Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Newsy (July 24, 2014) Sheik Umar Khan has treated many of the people infected in the Ebola outbreak, and now he's become one of them. Video provided by Newsy
Powered by NewsLook.com
Condemned Man's US Execution Takes Nearly Two Hours

Condemned Man's US Execution Takes Nearly Two Hours

AFP (July 24, 2014) America's death penalty debate raged Thursday after it took nearly two hours for Arizona to execute a prisoner who lost a Supreme Court battle challenging the experimental lethal drug cocktail. Duration: 00:55 Video provided by AFP
Powered by NewsLook.com
Can Watching TV Make You Feel Like A Failure?

Can Watching TV Make You Feel Like A Failure?

Newsy (July 24, 2014) A study by German researchers claims watching TV while you're stressed out can make you feel guilty and like a failure. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

    Health News

      Environment News

        Technology News



          Save/Print:
          Share:

          Free Subscriptions


          Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

          Get Social & Mobile


          Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

          Have Feedback?


          Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
          Mobile: iPhone Android Web
          Follow: Facebook Twitter Google+
          Subscribe: RSS Feeds Email Newsletters
          Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins