Featured Research

from universities, journals, and other organizations

U Of MN Researchers Develop Tests For Devastating Cattle Disease

Date:
August 30, 2005
Source:
University of Minnesota
Summary:
Researchers at the University of Minnesota, working in collaboration with scientists at the USDA, have used genomic information to develop tests that can rapidly detect and differentiate the bacteria that causes Johne's disease, a chronic wasting disease found in cattle and other ruminant animals such as sheep, goats and deer.

Researchers at the University of Minnesota, working in collaborationwith scientists at the USDA, have used genomic information to developtests that can rapidly detect and differentiate the bacteria thatcauses Johne's disease, a chronic wasting disease found in cattle andother ruminant animals such as sheep, goats and deer. This research,scheduled to be published in the Aug. 30 issue of the Proceedings ofthe National Academy of Sciences, also provides the foundation for abetter understanding of the Johne's disease process and the design ofvaccines to prevent infection.

Johne's disease is devastating to the United States dairy industry,costing about $200 million per year due to reduced milk production.Estimates indicate that the disease is present in approximately 25percent of Minnesota's dairy herds. Because the bacterium that causesJohne's disease, Mycobacterium avium subspecies paratuberculosis, isslow growing in the laboratory, previous tests often took between 6 and18 weeks to process. The current study shows how genomic informationmay be used to develop highly specific, sensitive, and rapid tests forthe detection of infected animals.

These new tests, which enable detection of the bacterium in fecalmatter or milk, can be completed in 72 hours or less with an accuracythat was not possible without knowledge of the complete genome of thebacterium. Since animals shed the bacteria in their milk, fasterdiagnosis will likely help monitor and improve the quality of dairyfoods.

"Since the results of this new test are available much sooner, infectedanimals can be identified and isolated more quickly, thereby providingan opportunity to minimize economic losses to the herd, and breakingthe chain of transmission from animal to animal," said Vivek Kapur,BVSc., Ph.D., principal investigator, faculty member of theUniversity's Medical School and College of Veterinary Medicine, anddirector of the Biomedical Genomics Center. In 2003, Kapur and hiscolleagues at the University of Minnesota were also awarded one of thelargest research grants by the USDA to form a national consortium tostudy Johne's disease in cattle.

Mycobacterium avium subspecies paratuberculosis is also implicated as afactor in Crohn's disease, an inflammatory bowel disease in humans.Infection with this bacterium in humans and all animals is generallybelieved to occur at an early age, with clinical manifestations of thedisease only showing up after several years. In the future, researchersare likely to be able to use this information to work on a test todetect these bacteria in blood or tissue of patients with Crohn'sdisease and ulcerative colitis.

"This research both advances knowledge of the basic science issuessurrounding the disease as well as applies that knowledge for immediatebenefits to animal and potentially human, health," said SagarikaKanjilal, associate professor of medicine, and a co-author of the paper.

###

Funding for the project was provided in part by grants from the U.S.Department of Agriculture Cooperative State Research, Education, andExtension Service National Research Initiative, and the AgriculturalResearch Service.


Story Source:

The above story is based on materials provided by University of Minnesota. Note: Materials may be edited for content and length.


Cite This Page:

University of Minnesota. "U Of MN Researchers Develop Tests For Devastating Cattle Disease." ScienceDaily. ScienceDaily, 30 August 2005. <www.sciencedaily.com/releases/2005/08/050830072002.htm>.
University of Minnesota. (2005, August 30). U Of MN Researchers Develop Tests For Devastating Cattle Disease. ScienceDaily. Retrieved October 2, 2014 from www.sciencedaily.com/releases/2005/08/050830072002.htm
University of Minnesota. "U Of MN Researchers Develop Tests For Devastating Cattle Disease." ScienceDaily. www.sciencedaily.com/releases/2005/08/050830072002.htm (accessed October 2, 2014).

Share This



More Plants & Animals News

Thursday, October 2, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Attacking Superbugs

Attacking Superbugs

Ivanhoe (Oct. 1, 2014) — Two weapons hospitals can use to attack superbugs. Scientists in Ireland created a new gel resistant to superbugs, and a robot that can disinfect a room in minutes. Video provided by Ivanhoe
Powered by NewsLook.com
Cultural Learning In Wild Chimps Observed For The First Time

Cultural Learning In Wild Chimps Observed For The First Time

Newsy (Oct. 1, 2014) — Cultural transmission — the passing of knowledge from one animal to another — has been caught on camera with chimps teaching other chimps. Video provided by Newsy
Powered by NewsLook.com
Earth Has Lost Half Its Vertebrate Wildlife Since 1970: WWF

Earth Has Lost Half Its Vertebrate Wildlife Since 1970: WWF

Newsy (Sep. 30, 2014) — A new study published by the World Wide Fund for Nature found that more than half of the world's wildlife population has declined since 1970. Video provided by Newsy
Powered by NewsLook.com
Annual Dog Surfing Competition Draws California Crowds

Annual Dog Surfing Competition Draws California Crowds

AFP (Sep. 30, 2014) — The best canine surfers gathered for Huntington Beach's annual dog surfing competition, "Surf City, Surf Dog." Duration: 01:15 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins