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Budesonide Provides Lasting Relief For Crohn's Disease Patients

Date:
September 13, 2005
Source:
Blackwell Publishing Ltd.
Summary:
In a study published in The American Journal of Gastroenterology, researchers found that budesonide capsules are an effective treatment to prolong and maintain the period of remission of Crohn's disease. Previous studies have demonstrated that budesonide is effective for inducing remission of Crohn's disease.

In a study published in The American Journal of Gastroenterology,researchers found that budesonide capsules are an effective treatmentto prolong and maintain the period of remission of Crohn's Disease.Previous studies have demonstrated that budesonide is effective forinducing remission of Crohn's disease.

Four double-blind, placebo-controlled trials were conducted withidentical protocols in which patients with Crohn's Disease, andmedically induced remission, received a treatment of oral budesonidefor 12 months. Results showed that budesonide taken at 6 mg/day iseffective for prolonging time to relapse and for significantly reducingrates of relapse.

"Long-term treatment with budesonide is well-tolerated and thefrequency and types of adverse events are similar to placebo," stateslead researcher,William J. Sandborn, MD. "Safety of a long-termmedication is obviously important, but how well a patient toleratestheir medication is also important and can affect patient adherence totherapy."

Crohn's disease is a long-term disease that results from inflammationof the digestive tract. It is a debilitating sickness, even forpatients who are classified as having mild to moderate disease.Currently, there are no treatment options available that preventsrecurrence of symptoms.

"As stated, this disease is recurring in nature, so extending the timea patient can be symptom-free or with diminished symptoms is animportant feature of treatment. Budesonide capsules are a treatmentoption for Crohn's disease that has been shown in studies not only tobe very effective in relieving symptoms, but also in extending the timebefore patients experience a recurrence."

###

This study is published in The American Journal of Gastroenterology.

Dr.William J. Sandborn is a board certified gastroenterologist withspecific expertise in inflammatory bowel disease. He has publishedextensively in this field, both nationally and internationally.

About The American Journal of Gastroenterology
The American Journal of Gastroenterology, the official publication ofthe American College of Gastroenterology, is THE clinical journal forall practicing gastroenterologists, hepatologists and GI endoscopists.With an impact factor of 4.716, it is the authoritative clinical sourcein the field of gastroenterology. With a broad-based, rigorous,interdisciplinary approach, the journal presents the latest importantinformation in the field of gastroenterology including originalmanuscripts, meta-analyses and reviews, health economic papers, debatesand consensus statements of clinical relevance in gastroenterology. Thereports will highlight new observations and original research, resultswith innovative treatments and all other topics relevant to clinicalgastroenterology. Case reports highlighting disease mechanisms orparticularly important clinical observations and letters on articlespublished in the Journal are included.

About Blackwell Publishing
Blackwell Publishing is theworld's leading society publisher, partnering with more than 600academic and professional societies. Blackwell publishes over 750journals annually and, to date has published close to 6,000 text andreference books, across a wide range of academic, medical, andprofessional subjects.


Story Source:

The above story is based on materials provided by Blackwell Publishing Ltd.. Note: Materials may be edited for content and length.


Cite This Page:

Blackwell Publishing Ltd.. "Budesonide Provides Lasting Relief For Crohn's Disease Patients." ScienceDaily. ScienceDaily, 13 September 2005. <www.sciencedaily.com/releases/2005/09/050913123928.htm>.
Blackwell Publishing Ltd.. (2005, September 13). Budesonide Provides Lasting Relief For Crohn's Disease Patients. ScienceDaily. Retrieved September 2, 2014 from www.sciencedaily.com/releases/2005/09/050913123928.htm
Blackwell Publishing Ltd.. "Budesonide Provides Lasting Relief For Crohn's Disease Patients." ScienceDaily. www.sciencedaily.com/releases/2005/09/050913123928.htm (accessed September 2, 2014).

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