Featured Research

from universities, journals, and other organizations

Drug-eluting Stents Succeed After Bare Metal Stents Fail

Date:
September 20, 2005
Source:
Society for Cardiovascular Angiography and Interventions
Summary:
Once a coronary stent becomes blocked with scar tissue, the likelihood it will become blocked again is 30 percent to 80 percent. Inserting a second coronary stent that slowly releases anti-scarring medication can markedly cut that risk, according to a study in the just-published October 2005 issue of Catheterization and Cardiovascular Interventions: Journal of the Society for Cardiovascular Angiography and Interventions.

BETHESDA, MD -- Once a coronary stent becomes blocked with scar tissue,the likelihood it will become blocked again is 30 percent to 80percent. Inserting a second coronary stent that slowly releasesanti-scarring medication can markedly cut that risk, according to astudy in the just-published October 2005 issue of Catheterization andCardiovascular Interventions: Journal of the Society for CardiovascularAngiography and Interventions.

Related Articles


Researchers also showed that it was unnecessary to thread a high-techultrasound device into the artery to guide precise placement of thedrug-eluting stent. Instead, they reduced the risk of blood clotting byminimizing trauma to the artery--no stretching of the artery before orafter the procedure, for example--and prescribing a double dose ofanti-clotting drugs for two months.

"Our slogan is not 'Bigger is better,' but 'A nice, quick jobis better,'" said Dr. Philippe Commeau, of Centre Hospitalier PriveBeauregard in Marseille, France.

Twenty-three patients participated in the ISR II study. All hadin-stent restenosis (ISR), an overgrowth of scar tissue inside a baremetal stent. They also had chest pain and some other sign that toolittle blood was flowing to the heart.

Patients were treated by insertion of a Cypher stent (CordisCorp., Miami) on top of the original bare metal stent. The Cypher stentslowly releases sirolimus into the artery wall, a medication thatprevent the overgrowth of the tissue that causes in-stent restenosis.Interventional cardiologists used standard x-ray angiography todetermine the correct placement of the stent.

During two years of follow-up, four patients (17 percent) hadyet another procedure to open the stented artery. Two of the patientshad no chest pain and showed no evidence of a shortfall of blood flowto the heart. Therefore, the study's authors pegged the true clinicalrestenosis rate at only 8.5 percent.

Since the conclusion of the ISR II study, Dr. Commeau and hiscolleagues have followed the progress of 200 similar patients for morethan two years. They expect to publish the results of that study soon.

###

Headquartered in Bethesda, Md., the Society for CardiovascularAngiography and Interventions is a 3,400-member professionalorganization representing invasive and interventional cardiologists.SCAI's mission is to promote excellence in invasive and interventionalcardiovascular medicine through physician education and representation,and advancement of quality standards to enhance patient care. SCAI wasorganized in 1976 under the guidance of Drs. F. Mason Sones and MelvinP. Judkins. The first SCAI Annual Scientific Sessions were held inChicago in 1978.



Story Source:

The above story is based on materials provided by Society for Cardiovascular Angiography and Interventions. Note: Materials may be edited for content and length.


Cite This Page:

Society for Cardiovascular Angiography and Interventions. "Drug-eluting Stents Succeed After Bare Metal Stents Fail." ScienceDaily. ScienceDaily, 20 September 2005. <www.sciencedaily.com/releases/2005/09/050920002346.htm>.
Society for Cardiovascular Angiography and Interventions. (2005, September 20). Drug-eluting Stents Succeed After Bare Metal Stents Fail. ScienceDaily. Retrieved November 1, 2014 from www.sciencedaily.com/releases/2005/09/050920002346.htm
Society for Cardiovascular Angiography and Interventions. "Drug-eluting Stents Succeed After Bare Metal Stents Fail." ScienceDaily. www.sciencedaily.com/releases/2005/09/050920002346.htm (accessed November 1, 2014).

Share This



More Health & Medicine News

Saturday, November 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Melafind: Spotting Melanoma Without a Biopsy

Melafind: Spotting Melanoma Without a Biopsy

Ivanhoe (Oct. 31, 2014) The MelaFind device is a pain-free way to check suspicious moles for melanoma, without the need for a biopsy. Video provided by Ivanhoe
Powered by NewsLook.com
Battling Multiple Myeloma

Battling Multiple Myeloma

Ivanhoe (Oct. 31, 2014) The answer isn’t always found in new drugs – repurposing an ‘old’ drug that could mean better multiple myeloma treatment, and hope. Video provided by Ivanhoe
Powered by NewsLook.com
Chronic Inflammation and Prostate Cancer

Chronic Inflammation and Prostate Cancer

Ivanhoe (Oct. 31, 2014) New information that is linking chronic inflammation in the prostate and prostate cancer, which may help doctors and patients prevent cancer in the future. Video provided by Ivanhoe
Powered by NewsLook.com
Sickle Cell: Stopping Kids’ Silent Strokes

Sickle Cell: Stopping Kids’ Silent Strokes

Ivanhoe (Oct. 31, 2014) Blood transfusions are proving crucial to young sickle cell patients by helping prevent strokes, even when there is no outward sign of brain injury. Video provided by Ivanhoe
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins