Featured Research

from universities, journals, and other organizations

Erectile Dysfunction May Signal Early Atherosclerosis

Date:
October 12, 2005
Source:
American College of Cardiology
Summary:
Erectile dysfunction may be a sign that coronary artery disease is developing, even in men without typical risk factors, according to a new study in the Oct. 18, 2005, issue of the Journal of the American College of Cardiology.

BETHESDA, MD -- Erectile dysfunction may be a sign that coronaryartery disease is developing, even in men without typical risk factors,according to a new study in the Oct. 18, 2005, issue of the Journal ofthe American College of Cardiology.

Related Articles


"We think that erectile dysfunction represents the 'tip of theiceberg' of a systemic vascular disorder; thus potentially precedingsevere cardiovascular events. Erectile dysfunction should be part of acardiovascular risk assessment. These patients should be considered athigh risk for coronary artery disease and should have high priority foraggressive treatment," said Emilio Chiurlia, Ph.D. from the Universityof Modena and Reggio Emilia in Modena, Italy.

The researchers studied 70 men with erectile dysfunction and 73control subjects who were of similar age and race (all Caucasian), andhad similar coronary risk factor scores according to estimatespublished by the National Cholesterol Education Panel III. None of themen had symptoms of coronary atherosclerosis.

The men with erectile dysfunction had higher levels ofC-reactive protein (an emerging coronary risk factor), they were morelikely to have abnormal blood vessel responses to changes in blood flow(as measured by flow mediated dilation), and more of them had coronaryartery calcifications detected on coronary CT scans.

"When a man is diagnosed with erectile dysfunction, cliniciansshould be aware that erectile dysfunction would represent an earlyclinical manifestation of a diffuse subclinical vascular disease andcoronary artery disease is the most important problem that needs to beinvestigated. The smaller penile arteries suffer obstruction fromplaque burden earlier than the larger coronary arteries hence erectiledysfunction may be symptomatic before a coronary event," Dr. Chiurliasaid.

Dr. Chiurlia noted that this study involved only a small numberof men and did not follow them over time to see which ones actuallydeveloped heart disease.

"We need prospective studies addressing the precise role oferectile dysfunction as a marker of cardiovascular disease," he said.

While awaiting the results of such future studies, he saiderectile dysfunction should raise suspicions about earlyatherosclerosis, even in men who would not otherwise be considered athigh risk.

"In our opinion, erectile dysfunction should be considered, like diabetes, a 'cardiovascular equivalent,'" Dr. Chiurlia said.

Renke Maas, M.D., from the University-Hospital Hamburg-Eppendorfin Hamburg, Germany, who was not connected with this research, agreedwith the main conclusion of the study.

"The present study by Chiurlia et al. lends strong support tothe notion that erectile dysfunction may be an early warning sign ofclinically-silent coronary artery disease. Despite limitations set bysample size and the cross-sectional study design with a long list ofexclusion criteria, it is a strength of the present work that itassesses major aspects connecting erectile dysfunction and moregeneralized vascular disease in one study," Dr. Maas said.

Paul Schoenhagen, M.D., from the Cleveland Clinic Foundation inCleveland, Ohio, who also was not connected with the research, said itprovides evidence of related problems in two different regions of thearterial tree.

"These results demonstrate the systemic nature ofatherosclerosis and the relationship to an inflammatory process of thevessel wall. This understanding of atherosclerosis increasingly allowsearly interventions aimed at the prevention of disease complications,"Dr. Schoenhagen said.



Story Source:

The above story is based on materials provided by American College of Cardiology. Note: Materials may be edited for content and length.


Cite This Page:

American College of Cardiology. "Erectile Dysfunction May Signal Early Atherosclerosis." ScienceDaily. ScienceDaily, 12 October 2005. <www.sciencedaily.com/releases/2005/10/051012231352.htm>.
American College of Cardiology. (2005, October 12). Erectile Dysfunction May Signal Early Atherosclerosis. ScienceDaily. Retrieved November 26, 2014 from www.sciencedaily.com/releases/2005/10/051012231352.htm
American College of Cardiology. "Erectile Dysfunction May Signal Early Atherosclerosis." ScienceDaily. www.sciencedaily.com/releases/2005/10/051012231352.htm (accessed November 26, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Wednesday, November 26, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

Newsy (Nov. 25, 2014) — The US FDA is announcing new calorie rules on Tuesday that will require everywhere from theaters to vending machines to include calorie counts. Video provided by Newsy
Powered by NewsLook.com
Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Newsy (Nov. 25, 2014) — Need another reason to eat yogurt every day? Researchers now say it could reduce a person's risk of developing type 2 diabetes. Video provided by Newsy
Powered by NewsLook.com
Madagascar Working to Contain Plague Outbreak

Madagascar Working to Contain Plague Outbreak

AFP (Nov. 24, 2014) — Madagascar said Monday it is trying to contain an outbreak of plague -- similar to the Black Death that swept Medieval Europe -- that has killed 40 people and is spreading to the capital Antananarivo. Duration: 00:42 Video provided by AFP
Powered by NewsLook.com
Are Female Bosses More Likely To Be Depressed?

Are Female Bosses More Likely To Be Depressed?

Newsy (Nov. 24, 2014) — A new study links greater authority with increased depressive symptoms among women in the workplace. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins