Featured Research

from universities, journals, and other organizations

Insulin Levels In African American Children Worsen Through Puberty

Date:
March 10, 2006
Source:
University of Alberta
Summary:
Insulin levels in African American children worsen as they progress through puberty while those same levels don't change in their Caucasian counterparts, says new University of Alberta research that shows puberty is a key developmental period affecting diabetes risk.

Insulin levels in African American children worsen as they progress through puberty while those same levels don't change in their Caucasian counterparts, says new University of Alberta research that shows puberty is a key developmental period affecting diabetes risk.

Dr. Geoff Ball, from the Faculty of Medicine and Dentistry at the U of A, was part of a team of researchers who conducted a unique longitudinal study that looked into the underlying physical and ethnicity-specific characteristics of insulin resistance in childhood and adolescence. They evaluated the dynamics of insulin sensitivity, insulin secretion and pancreatic beta-cell function in African American and Caucasian children through the stages of puberty. The research, which included investigators from the University of Southern California, Tufts University and the University of Alabama at Birmingham, was recently published in "The Journal of Pediatrics."

The study took place in Alabama over seven years, where participants were part of an ongoing study of body composition, energy expenditure and risk factors for Type 2 diabetes and cardiovascular disease. "This was a unique opportunity to be able to examine puberty-related health changes in these boys and girls," said Ball. "It has been difficult for researchers to previously study whether the effects of puberty differ across ethnic groups, so we were fortunate. We're studying the early genesis of what might lead to Type 2 diabetes and it will give us a clearer understanding of physiological changes that can help explain health risks."

The study confirmed that African American kids are more insulin resistant than Caucasian kids. None of the boys and girls were diagnosed with Type 2 diabetes, but insulin levels were markedly different between the two ethnic groups. The measure of pancreatic beta-cell function decreased in African American youth throughout puberty while the level remained static in Caucasian kids. These data demonstrated that puberty may have a unique effect on beta cell compensation to insulin resistance in young African Americans.

Puberty is a transient phase that may act as an accelerator to increase diabetes risk in some individuals, said Ball, also director of the Pediatric Centre for Weight and Health (PCWH) at the Stollery Children's Hospital in Edmonton. Insulin sensitivity usually decreases at puberty onset, but most often returns to normal afterwards. Our data reveal that a return to normal or baseline levels may not occur in all children, including African Americans, who we know are at increased risk of Type 2 diabetes," he said. "Puberty is just one part of this picture; we need to consider a host of factors that contribute to diabetes risk , but we now know that physiological changes during puberty may make an important contribution to the risk profile."


Story Source:

The above story is based on materials provided by University of Alberta. Note: Materials may be edited for content and length.


Cite This Page:

University of Alberta. "Insulin Levels In African American Children Worsen Through Puberty." ScienceDaily. ScienceDaily, 10 March 2006. <www.sciencedaily.com/releases/2006/03/060310101814.htm>.
University of Alberta. (2006, March 10). Insulin Levels In African American Children Worsen Through Puberty. ScienceDaily. Retrieved September 20, 2014 from www.sciencedaily.com/releases/2006/03/060310101814.htm
University of Alberta. "Insulin Levels In African American Children Worsen Through Puberty." ScienceDaily. www.sciencedaily.com/releases/2006/03/060310101814.htm (accessed September 20, 2014).

Share This



More Health & Medicine News

Saturday, September 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Sierra Leone's Nationwide Ebola Curfew Underway

Sierra Leone's Nationwide Ebola Curfew Underway

Newsy (Sep. 20, 2014) Sierra Leone is locked down as aid workers and volunteers look for new cases of Ebola. Video provided by Newsy
Powered by NewsLook.com
Changes Found In Brain After One Dose Of Antidepressants

Changes Found In Brain After One Dose Of Antidepressants

Newsy (Sep. 19, 2014) A study suggest antidepressants can kick in much sooner than previously thought. Video provided by Newsy
Powered by NewsLook.com
Could Grief Affect The Immune Systems Of Senior Citizens?

Could Grief Affect The Immune Systems Of Senior Citizens?

Newsy (Sep. 19, 2014) The study found elderly people are much more likely to become susceptible to infection than younger adults going though a similar situation. Video provided by Newsy
Powered by NewsLook.com
Jury Delivers Verdict in Salmonella Trial

Jury Delivers Verdict in Salmonella Trial

AP (Sep. 19, 2014) A federal jury has convicted three people in connection with an outbreak of salmonella poisoning five years ago that sickened hundreds of people and was linked to a number of deaths. (Sept. 19) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins