Featured Research

from universities, journals, and other organizations

The Cytokine Diet: The Next Fad In Weight Loss?

Date:
June 28, 2006
Source:
University of Pittsburgh Medical Center
Summary:
Might we be able to turn our immune system against another kind of foe besides infections and viruses? How about fat? Researchers from the Centre National de la Recherche Scientifique at the Pasteur Institute and the University of Lille, France, have evidence suggesting the possibility. The cytokine interleukin-7 (IL-7), an element of the immune system that is critical for maintaining the proper store of immune cells, also prevents obesity-prone mice from getting fat.

Might we be able to turn our immune system against another kind of foe besides infections and viruses? How about fat? Researchers from the Centre National de la Recherche Scientifique (CNRS) at the Pasteur Institute and the University of Lille, France, have evidence suggesting the possibility.

The cytokine interleukin-7 (IL-7), an element of the immune system that is critical for maintaining the proper store of immune cells, also prevents obesity-prone mice from getting fat, the researchers report at the 6th International Congress of Neuroendocrinology (ICN 2006) in Pittsburgh June 19–22 at the David L. Lawrence Convention Center.

The researchers used a common mouse model for obesity that involves inducing lesions in the hypothalamus--a part of the brain that regulates appetite--using a common food additive, monosodium glutamate (MSG). As expected, these mice packed on extra ounces--up to 28 percent of their normal body weight. Another set of mice was injected with a single infusion of IL-7 after being given MSG. Interestingly, these mice neither developed lesions nor did they gain weight. According to doctoral student Laurence Macia and co-authors, the results indicate for the first time that IL-7 interacts with the hypothalamus, and moreover, this interaction is related to the brain's regulation of appetite. Perhaps the immune and neuroendocrine systems are more closely linked than previously thought, they conclude.

Held in a different part of the world every four years under the auspices of the International Neuroendocrine Federation, this year's congress--Bridging Neuroscience and Endocrinology--is being sponsored by the American Neuroendocrine Society and the University of Pittsburgh School of Medicine. The first full day of the program, June 20, is being held in conjunction with the 10th Annual Meeting of the Society for Behavioral Neuroendocrinology.

Formerly the International Society of Neuroendocrinology, the International Neuroendocrine Federation consists of six member societies and seven regional groups, representing all parts of the world. The federation's president is John A. Russell, MBChB, Ph.D., chair of neuroendocrinology, University of Edinburgh. The chair of the ICN 2006 scientific program is Iain J. Clarke, Ph.D., professorial fellow in the department of physiology at Monash University in Australia. Tony Plant, Ph.D., professor of cell biology and physiology and director of the Center for Research in Reproductive Physiology, University of Pittsburgh School of Medicine, is chair of the local organizing committee.


Story Source:

The above story is based on materials provided by University of Pittsburgh Medical Center. Note: Materials may be edited for content and length.


Cite This Page:

University of Pittsburgh Medical Center. "The Cytokine Diet: The Next Fad In Weight Loss?." ScienceDaily. ScienceDaily, 28 June 2006. <www.sciencedaily.com/releases/2006/06/060628100425.htm>.
University of Pittsburgh Medical Center. (2006, June 28). The Cytokine Diet: The Next Fad In Weight Loss?. ScienceDaily. Retrieved August 28, 2014 from www.sciencedaily.com/releases/2006/06/060628100425.htm
University of Pittsburgh Medical Center. "The Cytokine Diet: The Next Fad In Weight Loss?." ScienceDaily. www.sciencedaily.com/releases/2006/06/060628100425.htm (accessed August 28, 2014).

Share This




More Health & Medicine News

Thursday, August 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Killer Amoeba Found in Louisiana Water System

Killer Amoeba Found in Louisiana Water System

AP (Aug. 28, 2014) State health officials say testing has confirmed the presence of a killer amoeba in a water system serving three St. John the Baptist Parish towns. (Aug. 28) Video provided by AP
Powered by NewsLook.com
Who Could Be Burnt by WHO's E-Cigs Move?

Who Could Be Burnt by WHO's E-Cigs Move?

Reuters - Business Video Online (Aug. 28, 2014) The World Health Organisation has called for the regulation of electronic cigarettes as both tobacco and medical products. Ciara Lee looks at the impact of the move on the tobacco industry. Video provided by Reuters
Powered by NewsLook.com
CDC Director On Ebola Outbreak: 'It's Worse Than I Feared'

CDC Director On Ebola Outbreak: 'It's Worse Than I Feared'

Newsy (Aug. 28, 2014) CDC director Tom Frieden says the Ebola outbreak is even worse than he feared. But he also said there's still hope to contain it. Video provided by Newsy
Powered by NewsLook.com
How A 'Rule Of Thumb' Could Slow Down Drinking

How A 'Rule Of Thumb' Could Slow Down Drinking

Newsy (Aug. 28, 2014) A study suggests people who follow a "rule of thumb" when pouring wine dispense less than those who don't have a particular amount in mind. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins