Featured Research

from universities, journals, and other organizations

Drug Could Change The Standard Treatment During Procedures To Clear Blocked Arteries

Date:
September 8, 2006
Source:
University of Kentucky
Summary:
Millions of procedures to open up blocked arteries feeding the heart are successfully performed at hospitals across the United States each year. Researchers are working to make what has become a relatively safe procedure even safer by finding a new drug that will effectively prevent blood clots and not put patients at risk for unnecessary bleeding. This study, which was designed to test the safety of enoxaparin, is one of the first steps cardiologists are taking to reach that goal.

A study led by a University of Kentucky researcher being published in the country's leading medical journal could one day change the standard treatment for preventing blood clots during procedures to open up blocked arteries feeding the heart.

Dr. Steven Steinhubl, co-chairman and senior author of a study appearing in the current issue of the New England Journal of Medicine, said the drug used in the study, enoxaparin, has the potential to become a standard treatment in stent and angioplasty procedures, but more research is necessary to come to a definitive conclusion. The current standard of care is to give patients unfractionated heparin.

Steinhubl, an interventional cardiologist and researcher at UK's Linda and Jack Gill Heart Institute, said that while elective stent and angioplasty procedures to clear blocked arteries are generally safe, a small percentage of patients will experience significant bleeding due to the procedure that can increase the cost and duration of the hospital stay and, in rare instances, even cause death.

In the study, researchers examined enoxaparin to determine if it is a safe and effective anti-clotting drug, carrying less risk for bleeding following the procedure than unfractionated heparin.

The study found that major bleeding was cut by more than half in patients receiving enoxaparin. It also showed that doctors were much more likely to achieve the targeted level of blood thinning for their patients with enoxaparin compared with unfractionated heparin.

"Bleeding following a stent placement or angioplasty is an event that is not only dangerous for patients, but also carries a financial burden for the health care industry as a whole," Steinhubl said. "Millions of these procedures are successfully performed at hospitals across the United States each year. It is important that we make what has become a relatively safe procedure even safer by finding a drug that will effectively prevent blood clots and not put patients at risk for unnecessary bleeding. This study, which was designed to test the safety of enoxaparin, is one of the first steps we as cardiologists are taking to reach that goal."


Story Source:

The above story is based on materials provided by University of Kentucky. Note: Materials may be edited for content and length.


Cite This Page:

University of Kentucky. "Drug Could Change The Standard Treatment During Procedures To Clear Blocked Arteries." ScienceDaily. ScienceDaily, 8 September 2006. <www.sciencedaily.com/releases/2006/09/060908150109.htm>.
University of Kentucky. (2006, September 8). Drug Could Change The Standard Treatment During Procedures To Clear Blocked Arteries. ScienceDaily. Retrieved August 22, 2014 from www.sciencedaily.com/releases/2006/09/060908150109.htm
University of Kentucky. "Drug Could Change The Standard Treatment During Procedures To Clear Blocked Arteries." ScienceDaily. www.sciencedaily.com/releases/2006/09/060908150109.htm (accessed August 22, 2014).

Share This




More Health & Medicine News

Friday, August 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Drug Used To Treat 'Ebola's Cousin' Shows Promise

Drug Used To Treat 'Ebola's Cousin' Shows Promise

Newsy (Aug. 21, 2014) An experimental drug used to treat Marburg virus in rhesus monkeys could give new insight into a similar treatment for Ebola. Video provided by Newsy
Powered by NewsLook.com
Two US Ebola Patients Leave Hospital Free of the Disease

Two US Ebola Patients Leave Hospital Free of the Disease

AFP (Aug. 21, 2014) Two American missionaries who were sickened with Ebola while working in Liberia and were treated with an experimental drug are doing better and have left the hospital, doctors say on August 21, 2014. Duration: 01:05 Video provided by AFP
Powered by NewsLook.com
Cadavers, a Teen, and a Medical School Dream

Cadavers, a Teen, and a Medical School Dream

AP (Aug. 21, 2014) Contains graphic content. He's only 17. But Johntrell Bowles has wanted to be a doctor from a young age, despite the odds against him. He was recently the youngest participant in a cadaver program at the Indiana University NW medical school. (Aug. 21) Video provided by AP
Powered by NewsLook.com
American Ebola Patients Released: What Cured Them?

American Ebola Patients Released: What Cured Them?

Newsy (Aug. 21, 2014) It's unclear whether the American Ebola patients' recoveries can be attributed to an experimental drug or early detection and good medical care. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins