Featured Research

from universities, journals, and other organizations

Stronger Leg Muscles Can Protect Against Knee Osteoarthritis

Date:
December 27, 2006
Source:
Mayo Clinic
Summary:
Stronger quadriceps muscles in the legs can help protect against cartilage loss behind the kneecap, according to Mayo Clinic researchers presenting preliminary study data at the American College of Rheumatology Annual Meeting on Nov. 15.

Stronger quadriceps muscles in the legs can help protect against cartilage loss behind the kneecap, according to Mayo Clinic researchers presenting preliminary study data at the American College of Rheumatology Annual Meeting on Nov. 15.

Related Articles


Knee osteoarthritis (OA) occurs when the cartilage that cushions the ends of the bones in the knee joint deteriorates over time. As this cushion wears down, the joint doesn't function as well and may be painful.

Mayo researchers, in collaboration with researchers from Boston University and the University of California, San Francisco, studied 265 men and women diagnosed with knee OA. They performed magnetic resonance images (MRIs) of participants' knee joints at the beginning of the study and again at 15 months and 30 months. Based on these MRIs, researchers determined how much cartilage loss occurred over time at the two joints of the knee: the tibiofemoral joint, where the thigh bone (femur) meets the lower leg bone (tibia); and the patellofemoral joint, behind the kneecap (patella).

When the study began, researchers also had measured the strength of participants' quadriceps muscles (leg muscles in the upper thigh). Analyzing these measurements, researchers observed that participants who had greater quadriceps strength had less cartilage loss within the lateral compartment of the patellofemoral joint, which is frequently affected by OA.

"A stronger quadriceps muscle helps keep the patella from moving laterally and tracking abnormally with movement," says Shreyasee Amin, M.D., Mayo rheumatologist and the study's lead researcher. "Our study results emphasize that it's important to encourage people with knee osteoarthritis to maintain strong quadriceps muscles as recommended by their physician."

The exact cause of OA isn't known. Researchers suspect a combination of factors, including being overweight, the aging process, joint injury or stress, heredity and muscle weakness. Pain is the major complication of OA. The degree of pain can vary greatly, from mild inconvenience to a debilitating condition that interferes with daily activities.

Other members of this Mayo-led research team included: Kristin Baker, Ph.D., Jingbo Niu, M.D.; D.Sc., Joyce Goggins; David Hunter, M.B.B.S., Ph.D.; and David Felson, M.D., all from Boston University; and Ali Guermazi, M.D.; Mikayel Grigoryan, M.D.; both from the University of California, San Francisco. This work was supported by grants from the Arthritis Foundation, the National Institutes of Health and the Bayer Corporation.


Story Source:

The above story is based on materials provided by Mayo Clinic. Note: Materials may be edited for content and length.


Cite This Page:

Mayo Clinic. "Stronger Leg Muscles Can Protect Against Knee Osteoarthritis." ScienceDaily. ScienceDaily, 27 December 2006. <www.sciencedaily.com/releases/2006/11/061116100945.htm>.
Mayo Clinic. (2006, December 27). Stronger Leg Muscles Can Protect Against Knee Osteoarthritis. ScienceDaily. Retrieved November 1, 2014 from www.sciencedaily.com/releases/2006/11/061116100945.htm
Mayo Clinic. "Stronger Leg Muscles Can Protect Against Knee Osteoarthritis." ScienceDaily. www.sciencedaily.com/releases/2006/11/061116100945.htm (accessed November 1, 2014).

Share This



More Health & Medicine News

Saturday, November 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Melafind: Spotting Melanoma Without a Biopsy

Melafind: Spotting Melanoma Without a Biopsy

Ivanhoe (Oct. 31, 2014) The MelaFind device is a pain-free way to check suspicious moles for melanoma, without the need for a biopsy. Video provided by Ivanhoe
Powered by NewsLook.com
Battling Multiple Myeloma

Battling Multiple Myeloma

Ivanhoe (Oct. 31, 2014) The answer isn’t always found in new drugs – repurposing an ‘old’ drug that could mean better multiple myeloma treatment, and hope. Video provided by Ivanhoe
Powered by NewsLook.com
Chronic Inflammation and Prostate Cancer

Chronic Inflammation and Prostate Cancer

Ivanhoe (Oct. 31, 2014) New information that is linking chronic inflammation in the prostate and prostate cancer, which may help doctors and patients prevent cancer in the future. Video provided by Ivanhoe
Powered by NewsLook.com
Sickle Cell: Stopping Kids’ Silent Strokes

Sickle Cell: Stopping Kids’ Silent Strokes

Ivanhoe (Oct. 31, 2014) Blood transfusions are proving crucial to young sickle cell patients by helping prevent strokes, even when there is no outward sign of brain injury. Video provided by Ivanhoe
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins