Featured Research

from universities, journals, and other organizations

Potential For Malaria Transmission Higher Than Previously Thought

Date:
February 20, 2007
Source:
Public Library of Science
Summary:
A new mathematical approach applied to 121 human populations infected with malaria revises the basic reproductive number -- an indication of the transmission intensity -- up by an order of magnitude, with serious implications for effective malaria control.

Each year, malaria results in more than a million deaths. Controlling this disease involves understanding its transmission, and understanding its transmission means understanding its basic reproductive number, R0. For all infectious disease, R0 describes the most important aspects of transmission as it is the expected number of hosts that can trace their infection directly back to a single host after one disease generation. For vector-borne diseases, such as malaria, R0 is given by a classic formula.

In a new study published in PLoS Biology, David Smith and colleagues demonstrate that estimates of R0 range from around one to over 3,000, providing much higher estimates than previously thought, with serious implications for the control of the disease.

The author provides 121 estimates of R0 for Plasmodium falciparum malaria in African populations. In addition to the higher estimates of R0, they also show that in small human populations, R0 approximates transmission when counting infections from mosquito to mosquito, but overestimates it from human to human. Previous studies showed that transmission is amplified if some humans are bitten more than others.

The authors confirm that such heterogeneous biting amplifies transmission counting from mosquito to mosquito, but it can also dampen transmission counting from human to human. Humans who are bitten most both infect a large number of mosquitoes and absorb many infectious bites.

What does this mean for control? When R0 is in the thousands, eliminating malaria may seem impossible. If transmission from the humans who are bitten the most can be targeted, however, local elimination can still be within reach.

Citation: Smith DL, McKenzie FE, Snow RW, Hay SI (2007) Revisiting the basic reproductive number for malaria and its implications for malaria control. PLoS Biol 5(3): e42. doi:10.1371/journal.pbio.0050042.


Story Source:

The above story is based on materials provided by Public Library of Science. Note: Materials may be edited for content and length.


Cite This Page:

Public Library of Science. "Potential For Malaria Transmission Higher Than Previously Thought." ScienceDaily. ScienceDaily, 20 February 2007. <www.sciencedaily.com/releases/2007/02/070220020810.htm>.
Public Library of Science. (2007, February 20). Potential For Malaria Transmission Higher Than Previously Thought. ScienceDaily. Retrieved October 20, 2014 from www.sciencedaily.com/releases/2007/02/070220020810.htm
Public Library of Science. "Potential For Malaria Transmission Higher Than Previously Thought." ScienceDaily. www.sciencedaily.com/releases/2007/02/070220020810.htm (accessed October 20, 2014).

Share This



More Health & Medicine News

Monday, October 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

How Nigeria Beat Its Ebola Outbreak

How Nigeria Beat Its Ebola Outbreak

Newsy (Oct. 20, 2014) The World Health Organization has declared Nigeria free of Ebola. Health experts credit a bit of luck and the government's initial response. Video provided by Newsy
Powered by NewsLook.com
Another Study Suggests Viagra Is Good For The Heart

Another Study Suggests Viagra Is Good For The Heart

Newsy (Oct. 20, 2014) An ingredient in erectile-dysfunction medications such as Viagra could improve heart function. Perhaps not surprising, given Viagra's history. Video provided by Newsy
Powered by NewsLook.com
Ebola Worries End for Dozens on U.S. Watch Lists

Ebola Worries End for Dozens on U.S. Watch Lists

Reuters - US Online Video (Oct. 20, 2014) Forty-three people who had contact with Thomas Eric Duncan, the first person diagnosed with Ebola in the U.S., were cleared overnight of twice-daily monitoring after 21 days of showing no symptoms. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com
Fauci: Ebola Protocols to Focus on Training

Fauci: Ebola Protocols to Focus on Training

AP (Oct. 20, 2014) Dr. Anthony Fauci, head of the National Institute of Allergy and Infectious Diseases, says he expects revised CDC protocols on Ebola to focus on training, observation and ensuring health care workers are more protected. (Oct. 20) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins