Featured Research

from universities, journals, and other organizations

Pay More Attention To Genital Herpes Infections In HIV-infected Persons, Editorial Urges

Date:
February 25, 2007
Source:
Fred Hutchinson Cancer Research Center
Summary:
The association between genital herpes and higher viral loads of HIV-1 in HIV-infected persons is strong enough to warrant more routine testing for the herpes virus in HIV-positive patients, as well as additional clinical studies of the co-infections, according to an editorial to be published in the Feb. 22 New England Journal of Medicine.

The association between genital herpes and higher viral loads of HIV-1 in HIV-infected persons is strong enough to warrant more routine testing for the herpes virus in HIV-positive patients, as well as additional clinical studies of the co-infections, according to an editorial to be published in the Feb. 22 New England Journal of Medicine.

Related Articles


"The clinical management of herpes simplex virus type 2 (HSV-2) in patients with HIV infection has lagged seriously behind the large body of medical literature on the importance of the interaction between these two pathogens," writes Larry Corey, M.D., principal investigator of the HIV Vaccine Trials Network at Fred Hutchinson Cancer Research Center, and head of the Infectious Diseases Program and Virology Division at the University of Washington School of Medicine. Corey's commentary relates to the paper by Nicolas Nagot, M.D., and colleagues in the same issue of the journal,

"Reduction of HIV-1 RNA levels with therapy to suppress herpes simplex virus." Researchers found that treating HSV-2 infections reduces genital and systemic levels of HIV-1 RNA. Repeated studies have shown that HSV-2 increases the amount of HIV-1 in plasma and genital secretions. The research group led by Corey at the Hutchinson Center was the first to note the association between HSV-2 and HIV in studies done in Seattle in 1988. The Nagot paper builds upon the initial work the group did by showing that daily antiviral therapy to treat HSV-2 infection can reduce the replication rate of HIV-1.

"The demonstration that daily anti-HSV-2 therapy can reduce the viral load by this amount is thus of direct importance for treatment," Corey wrote. Corey urges clinicians to incorporate more routine testing for HSV-2 into the initial evaluation of HIV-positive patients. The Nagot paper "has direct clinical implications, suggesting that HIV-1 replication can be reduced with antiviral therapy directed solely at HSV-2," wrote Corey. Most people worldwide with sexually-acquired HIV have active HSV-2 infections: 30 percent to 70 percent in Europe and 50 percent to 90 percent in Africa, according to an earlier study by Corey.


Story Source:

The above story is based on materials provided by Fred Hutchinson Cancer Research Center. Note: Materials may be edited for content and length.


Cite This Page:

Fred Hutchinson Cancer Research Center. "Pay More Attention To Genital Herpes Infections In HIV-infected Persons, Editorial Urges." ScienceDaily. ScienceDaily, 25 February 2007. <www.sciencedaily.com/releases/2007/02/070222160450.htm>.
Fred Hutchinson Cancer Research Center. (2007, February 25). Pay More Attention To Genital Herpes Infections In HIV-infected Persons, Editorial Urges. ScienceDaily. Retrieved November 26, 2014 from www.sciencedaily.com/releases/2007/02/070222160450.htm
Fred Hutchinson Cancer Research Center. "Pay More Attention To Genital Herpes Infections In HIV-infected Persons, Editorial Urges." ScienceDaily. www.sciencedaily.com/releases/2007/02/070222160450.htm (accessed November 26, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Wednesday, November 26, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

Newsy (Nov. 25, 2014) — The US FDA is announcing new calorie rules on Tuesday that will require everywhere from theaters to vending machines to include calorie counts. Video provided by Newsy
Powered by NewsLook.com
Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Newsy (Nov. 25, 2014) — Need another reason to eat yogurt every day? Researchers now say it could reduce a person's risk of developing type 2 diabetes. Video provided by Newsy
Powered by NewsLook.com
Madagascar Working to Contain Plague Outbreak

Madagascar Working to Contain Plague Outbreak

AFP (Nov. 24, 2014) — Madagascar said Monday it is trying to contain an outbreak of plague -- similar to the Black Death that swept Medieval Europe -- that has killed 40 people and is spreading to the capital Antananarivo. Duration: 00:42 Video provided by AFP
Powered by NewsLook.com
Are Female Bosses More Likely To Be Depressed?

Are Female Bosses More Likely To Be Depressed?

Newsy (Nov. 24, 2014) — A new study links greater authority with increased depressive symptoms among women in the workplace. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins