Featured Research

from universities, journals, and other organizations

Smoking May Be A Risk Factor For Tuberculosis

Date:
March 1, 2007
Source:
JAMA and Archives Journals
Summary:
Smoking appears to increase the risk of becoming infected with tuberculosis and the risk for the development of active disease upon infection, according to an analysis of previously published research in the Feb. 26 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

Smoking appears to increase the risk of becoming infected with tuberculosis and the risk for the development of active disease upon infection, according to an analysis of previously published research in the February 26 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

Related Articles


About one-third of the world's population is infected with the bacteria that cause tuberculosis (TB), but the organism is usually rendered inactive by the immune system, according to background information in the article. Active tuberculosis developed in approximately 8.8 million individuals in 2003 and is responsible for about 1.7 million deaths worldwide each year. "It has long been suggested that tobacco smoking may affect rates of TB morbidity and mortality," the authors write. "This could be a result of increasing the risk of infection with TB mycobacteria, increasing the rate of active TB disease, or increasing the TB mortality rate; plausible mechanisms exist."

Michael N. Bates, Ph.D., and colleagues at the School of Public Health, University of California, Berkeley, performed a meta-analysis of 24 previously published studies that examined the association between smoking and TB. Six of the publications dealt with the risk for TB infection, 13 with active TB disease and five with death from TB.

Across the studies, individuals who smoked had a 73 percent increased risk of becoming infected with tuberculosis and were more than twice as likely to develop active tuberculosis than those who did not smoke. This suggests that smokers are 40 to 60 percent more likely than non-smokers to develop tuberculosis disease after being infected with TB bacteria. The excess risk of death from TB associated with smoking was less than the excess risk of TB disease, suggesting that smoking does not increase the risk of death among those who already have active TB.

There are several potential explanations for the association, although more research is needed to determine the mechanisms involved, the authors note. Smoking could decrease immune response or damage the function of cilia in the airways, increasing the risk for TB. "Tuberculosis control policies should in the future incorporate tobacco control as a preventive intervention," the authors write.

"Potentially, smoking is one of the most modifiable of exposures," they conclude. "In developing countries, where life expectancy is short, highlighting smoking as a risk factor for TB may have greater resonance than advertising its risks for cancer and cardiovascular disease."


Story Source:

The above story is based on materials provided by JAMA and Archives Journals. Note: Materials may be edited for content and length.


Cite This Page:

JAMA and Archives Journals. "Smoking May Be A Risk Factor For Tuberculosis." ScienceDaily. ScienceDaily, 1 March 2007. <www.sciencedaily.com/releases/2007/02/070227105634.htm>.
JAMA and Archives Journals. (2007, March 1). Smoking May Be A Risk Factor For Tuberculosis. ScienceDaily. Retrieved December 18, 2014 from www.sciencedaily.com/releases/2007/02/070227105634.htm
JAMA and Archives Journals. "Smoking May Be A Risk Factor For Tuberculosis." ScienceDaily. www.sciencedaily.com/releases/2007/02/070227105634.htm (accessed December 18, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, December 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Kids Die While Under Protective Services

Kids Die While Under Protective Services

AP (Dec. 18, 2014) As part of a six-month investigation of child maltreatment deaths, the AP found that hundreds of deaths from horrific abuse and neglect could have been prevented. AP's Haven Daley reports. (Dec. 18) Video provided by AP
Powered by NewsLook.com
UN: Up to One Million Facing Hunger in Ebola-Hit Countries

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

AFP (Dec. 17, 2014) Border closures, quarantines and crop losses in West African nations battling the Ebola virus could lead to as many as one million people going hungry, UN food agencies said on Wednesday. Duration: 00:52 Video provided by AFP
Powered by NewsLook.com
When You Lose Weight, This Is Where The Fat Goes

When You Lose Weight, This Is Where The Fat Goes

Newsy (Dec. 17, 2014) Can fat disappear into thin air? New research finds that during weight loss, over 80 percent of a person's fat molecules escape through the lungs. Video provided by Newsy
Powered by NewsLook.com
Why Your Boss Should Let You Sleep In

Why Your Boss Should Let You Sleep In

Newsy (Dec. 17, 2014) According to research out of the University of Pennsylvania, waking up for work is the biggest factor that causes Americans to lose sleep. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins