Featured Research

from universities, journals, and other organizations

Research To Explore Genetic Causes Of Autism

Date:
March 19, 2007
Source:
Yale University
Summary:
Researchers at the Yale School of Medicine Child Study Center and 10 other institutions will share a $10 million gift from James and Marilyn Simons of the Simons Foundation to create a databank of DNA samples from autism patients around the country. The goal is to collect a total of 3,000 samples from autism patients around the country to help identify different variants of autism and develop treatments.

Researchers at the Yale School of Medicine Child Study Center and 10 other institutions will share a $10 million gift from James and Marilyn Simons of The Simons Foundation to create a databank of DNA samples from autism patients around the country.

Related Articles


The goal is to collect a total of 3,000 samples from autism patients around the country to help identify different variants of autism and develop treatments. The principal investigators at Yale, Ami Klin and Matthew State, M.D., have received $1.2 million for three years to collect DNA samples from patients completing clinical evaluations or research protocols at the Autism Program at the Yale Child Study Center.

Autism is a complex brain disorder that inhibits a person's ability to communicate and develop social relationships, and it is often accompanied by extreme behavioral challenges. Autism Spectrum Disorders are diagnosed in one in 150 children in the United States and affects four times as many boys as girls. Researchers do not know how many subtypes of autism exist. Klin, the Harris Associate Professor of Child Psychology and Psychiatry at Yale, said the gene data might help identify meaningful subtypes of autism, thus advancing knowledge that is critical for behavioral and brain studies, and promoting treatments that will likely be more specific to an individual's variant of autism.

Other universities participating in the DNA databank collection include Harvard, Columbia, Emory, McGill, Boston, Washington University, the University of Washington, the University of Illinois-Chicago and the University of California, Los Angeles.

The Simons Consortium represents the most comprehensive and detailed effort to date to relate genotypic and phenotypic data in autism. Subjects completing the protocol will have the most refined genotypic analyses that can then be related to a wealth of data on the affected individuals themselves and on their family members. The Consortium will house the data in a centralized repository that will be accessible to researchers within and outside the institutions involved in this effort.

The Simons Foundation is a private family foundation based in New York City. The primary mission is to fund advanced research in science and mathematics. A secondary mission is to help children with learning differences. Bridging these two areas, the Simons Foundation has recently undertaken a major initiative supporting research into autism and its treatment. The Foundation aims to spend $100 million long-term to find a cure for the developmental disorder.


Story Source:

The above story is based on materials provided by Yale University. Note: Materials may be edited for content and length.


Cite This Page:

Yale University. "Research To Explore Genetic Causes Of Autism." ScienceDaily. ScienceDaily, 19 March 2007. <www.sciencedaily.com/releases/2007/03/070319161055.htm>.
Yale University. (2007, March 19). Research To Explore Genetic Causes Of Autism. ScienceDaily. Retrieved October 24, 2014 from www.sciencedaily.com/releases/2007/03/070319161055.htm
Yale University. "Research To Explore Genetic Causes Of Autism." ScienceDaily. www.sciencedaily.com/releases/2007/03/070319161055.htm (accessed October 24, 2014).

Share This



More Mind & Brain News

Friday, October 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Academic Scandal Shocks UNC

Academic Scandal Shocks UNC

AP (Oct. 23, 2014) A scandal involving bogus classes and inflated grades at the University of North Carolina was bigger than previously reported, a new investigation found. (Oct. 23) Video provided by AP
Powered by NewsLook.com
Working Mother Getaway: Beaches Turks & Caicos

Working Mother Getaway: Beaches Turks & Caicos

Working Mother (Oct. 22, 2014) Feast your eyes on this gorgeous family-friendly resort. Video provided by Working Mother
Powered by NewsLook.com
What Your Favorite Color Says About You

What Your Favorite Color Says About You

Buzz60 (Oct. 22, 2014) We all have one color we love to wear, and believe it or not, your color preference may reveal some of your character traits. In celebration of National Color Day, Krystin Goodwin (@kyrstingoodwin) highlights what your favorite colors may say about you. Video provided by Buzz60
Powered by NewsLook.com
First-Of-Its-Kind Treatment Gives Man Ability To Walk Again

First-Of-Its-Kind Treatment Gives Man Ability To Walk Again

Newsy (Oct. 21, 2014) A medical team has for the first time given a man the ability to walk again after transplanting cells from his brain onto his severed spinal cord. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins