Featured Research

from universities, journals, and other organizations

Getting Dirty May Lift Your Mood

Date:
April 10, 2007
Source:
University of Bristol
Summary:
Treatment of mice with a "friendly" bacteria, normally found in the soil, altered their behavior in a way similar to that produced by antidepressant drugs, reports research published in the latest issue of Neuroscience. These findings aid the understanding of why an imbalance in the immune system leaves some individuals vulnerable to mood disorders like depression.

Colonies of Mycobacterium vaccae grown on Sauton's agar.
Credit: Courtesy of co-author Laura Rosa Brunet, UCL

Bacteria found in the soil activated a group of neurons that produce the brain chemical serotonin.

Treatment of mice with a 'friendly' bacteria, normally found in the soil, altered their behavior in a way similar to that produced by antidepressant drugs, reports research published in the latest issue of Neuroscience.

These findings, identified by researchers at the University of Bristol and colleagues at University College London, aid the understanding of why an imbalance in the immune system leaves some individuals vulnerable to mood disorders like depression.

Dr Chris Lowry, lead author on the paper from Bristol University, said: "These studies help us understand how the body communicates with the brain and why a healthy immune system is important for maintaining mental health. They also leave us wondering if we shouldn't all be spending more time playing in the dirt."

Interest in the project arose after human cancer patients being treated with the bacteria Mycobacterium vaccae unexpectedly reported increases in their quality of life. Lowry and his colleagues reasoned that this effect could be caused by activation of neurons in the brain that contained serotonin.

When the team looked closely at the brains of mice, they found that treatment with M. vaccae activated a group of neurons that produce the brain chemical serotonin. The lack of serotonin in the brain is thought to cause depression in people, thus M. vaccae's effects on the behavior of mice may be due to increasing the release of serotonin in parts of the brain that regulate mood.

The new research supports this hypothesis, but future studies will be designed to determine if M. vaccae, other bacteria, or pharmaceutical compounds have antidepressant properties through activation of this group of serotonin neurons.


Story Source:

The above story is based on materials provided by University of Bristol. Note: Materials may be edited for content and length.


Cite This Page:

University of Bristol. "Getting Dirty May Lift Your Mood." ScienceDaily. ScienceDaily, 10 April 2007. <www.sciencedaily.com/releases/2007/04/070402102001.htm>.
University of Bristol. (2007, April 10). Getting Dirty May Lift Your Mood. ScienceDaily. Retrieved August 20, 2014 from www.sciencedaily.com/releases/2007/04/070402102001.htm
University of Bristol. "Getting Dirty May Lift Your Mood." ScienceDaily. www.sciencedaily.com/releases/2007/04/070402102001.htm (accessed August 20, 2014).

Share This




More Plants & Animals News

Wednesday, August 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Awesome New Camouflage Sheet Was Inspired By Octopus Skin

Awesome New Camouflage Sheet Was Inspired By Octopus Skin

Newsy (Aug. 19, 2014) Scientists have developed a new device that mimics the way octopuses blend in with their surroundings to hide from dangerous predators. Video provided by Newsy
Powered by NewsLook.com
Disquieting Times for Malaysia's 'fish Listeners'

Disquieting Times for Malaysia's 'fish Listeners'

AFP (Aug. 19, 2014) Malaysia's last "fish listeners" -- practitioners of a dying local art of listening underwater to locate their quarry -- try to keep the ancient technique alive in the face of industrial trawling and the depletion of stocks. Duration: 02:29 Video provided by AFP
Powered by NewsLook.com
USDA Cracks Down On Imports From Foreign Puppy Mills

USDA Cracks Down On Imports From Foreign Puppy Mills

Newsy (Aug. 18, 2014) New USDA measures to regulate dog imports aim to crack down on buying dogs from overseas puppy mills. Video provided by Newsy
Powered by NewsLook.com
Bone Marrow Drug Regrows Hair In Some Alopecia Patients

Bone Marrow Drug Regrows Hair In Some Alopecia Patients

Newsy (Aug. 18, 2014) Researchers performed an experiment using an FDA-approved drug known as ruxolitinib. They found it to be successful in the majority of patients. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins