Featured Research

from universities, journals, and other organizations

Determining Risks Of Second Cancers Among Survivors Of Cervical Cancer

Date:
April 17, 2007
Source:
American Association for Cancer Research
Summary:
Women diagnosed with cervical cancer tend to have good long-term survival, but they often have specific risk factors for developing a cancer later in life: a history of smoking, infection with the human papillomavirus, and/or treatment with radiation therapy.

Women diagnosed with cervical cancer tend to have good long-term survival, but they often have specific risk factors for developing a cancer later in life: a history of smoking, infection with the human papillomavirus, and/or treatment with radiation therapy.

A study by researchers in the U.S., Denmark, Finland, Sweden, and Norway has documented cervical cancer survivors' significantly increased risk of developing a second primary cancer--a risk that lasts for several decades after their initial diagnosis of invasive cervical cancer. Using 13 population-based cancer registries in Denmark, Finland, Sweden, Norway, as well as the U.S. Surveillance, Epidemiology, and End Results program, the researchers studied 104,760 cervical cancer survivors starting one year after their diagnosis and continuing over the next 40 years or more. They found that these women had a 30 percent higher incidence of all second cancers compared to women in the general population.

"The unique aspect of this study is the long length of follow up," said Anil Chaturvedi, Ph.D., MPH, a researcher at the Division of Cancer Epidemiology and Genetics, National Cancer Institute. "Previous studies had evaluated second cancer risk up to 30 years of follow up. With these registries, we were able to assess longer-term risk over 40 years or more."

The researchers examined the women's risk for specific cancers associated with smoking and HPV infection -- known causes of cervical cancer. "We did not have information on smoking in our study, but it has been well-documented that women with cervical cancer are more likely to have a history of smoking," Chaturvedi said.

Compared to women in the general population, risks for HPV-related cancers (oropharynx, female genital sites, and anus) and smoking-related cancers (lung, pancreas, and urinary bladder) were significantly elevated.

The researchers also compared second cancer risk in women who had radiation treatment versus women in the general population. Women who underwent radiation were at increased risk for any second cancer and cancers at heavily irradiated sites (colon, rectum/anus, urinary bladder, ovary, female genital sites) beyond 40 years of follow up.

"What's most significant is that even as far out as 40 years after diagnosis, these women have an increased risk for second cancers," Chaturvedi said. "These results suggest a need for close medical surveillance for second cancers."


Story Source:

The above story is based on materials provided by American Association for Cancer Research. Note: Materials may be edited for content and length.


Cite This Page:

American Association for Cancer Research. "Determining Risks Of Second Cancers Among Survivors Of Cervical Cancer." ScienceDaily. ScienceDaily, 17 April 2007. <www.sciencedaily.com/releases/2007/04/070416222756.htm>.
American Association for Cancer Research. (2007, April 17). Determining Risks Of Second Cancers Among Survivors Of Cervical Cancer. ScienceDaily. Retrieved September 19, 2014 from www.sciencedaily.com/releases/2007/04/070416222756.htm
American Association for Cancer Research. "Determining Risks Of Second Cancers Among Survivors Of Cervical Cancer." ScienceDaily. www.sciencedaily.com/releases/2007/04/070416222756.htm (accessed September 19, 2014).

Share This



More Health & Medicine News

Friday, September 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Could Grief Affect The Immune Systems Of Senior Citizens?

Could Grief Affect The Immune Systems Of Senior Citizens?

Newsy (Sep. 19, 2014) The study found elderly people are much more likely to become susceptible to infection than younger adults going though a similar situation. Video provided by Newsy
Powered by NewsLook.com
Jury Delivers Verdict in Salmonella Trial

Jury Delivers Verdict in Salmonella Trial

AP (Sep. 19, 2014) A federal jury has convicted three people in connection with an outbreak of salmonella poisoning five years ago that sickened hundreds of people and was linked to a number of deaths. (Sept. 19) Video provided by AP
Powered by NewsLook.com
How The 'Angelina Jolie Effect' Increased Cancer Screenings

How The 'Angelina Jolie Effect' Increased Cancer Screenings

Newsy (Sep. 19, 2014) Angelina's Jolie's decision to undergo a preventative mastectomy in 2013 inspired many women to seek early screenings for the disease. Video provided by Newsy
Powered by NewsLook.com
The Cost of Ebola

The Cost of Ebola

Reuters - Business Video Online (Sep. 18, 2014) As Sierra Leone prepares for a three-day "lockdown" in its latest bid to stem the spread of Ebola, Ciara Lee looks at the financial implications of fighting the largest ever outbreak of the disease. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins