Featured Research

from universities, journals, and other organizations

Collapse Of Teenage Clubber Highlights Dangers Of New Drug

Date:
April 29, 2007
Source:
The Lancet
Summary:
The collapse of a teenage clubber after taking a tablet containing 1-benzylpiperazine has highlighted the dangers of this new drug of abuse which many doctors are unfamiliar with, according to an article on the Lancet.

The collapse of a teenage clubber after taking a tablet containing 1-benzylpiperazine has highlighted the dangers of this new drug of abuse which many doctors are unfamiliar with, details a Case Report in the Lancet.

Related Articles


It was during a weekend in May 2006 that an 18-year-old girl was rushed to the emergency department of a London (UK) hospital, having collapsed in a nightclub after taking tablets she had bought from a drug dealer.

The girl was one of seven patients admitted to the department with similar symptoms (high blood pressure, Glasgow Coma rating of 15 and low body temperature of 35.9 degrees Celsius), and analysis of her blood and a subsequently seized tablet both revealed presence of 1-benzylpiperazine. Dr David Wood, Department of Clinical Toxicology, Guy’s and St Thomas’ NHS Foundation Trust, and colleagues, investigated the case and authored this Case Report.

The girl was treated with intravenous lorazepam and diazepam for her agitation, and was discharged after 12 hours with a warning to avoid recreational drugs.

Piperazines were developed as veterinary anthelmintic (worm removing) agents in the 1950s, and have chemical structures similar to amphetamine (also spelt amfetamine). They are marketed in the UK as the legal alternative to other recreational drugs such as ecstacy, and are available in shops and online.

The manufacturers of these drugs claim that 20 million pills containing piperazines have been consumed in New Zealand with no deaths or significant long term injuries. But these claims have been met with scepticism, since a prospective study in New Zealand revealed 80 cases of patients presenting at emergency departments with symptoms similar to those from taking amphetamines, such as nausea, vomiting, rapid heartbeat, anxiety and agitation. Seizures were reported in 15 of these cases after eight hours, with three patients experiencing potentially life threatening repeated seizures.

The authors conclude: “Clinicians should be aware of the potential presenting features of piperazine toxicity, particularly because commercially available urine toxicological screen kits for drugs of abuse may not detect piperazines.”

In an accompanying comment, Dr Roland Staack, Institute of Forensic Medicine, Ludwig Maximillian’s University, Munich, Germany, says that Piperazines and amphetamines are similarly marketed, consumed by the same population and show similar pharmacological symptoms.

He says: “Wood and colleagues case report is an excellent example to raise clinicians’ awareness of new drugs of abuse and substantiates the importance of a sound toxicological analysis for a correct clinical diagnosis.”


Story Source:

The above story is based on materials provided by The Lancet. Note: Materials may be edited for content and length.


Cite This Page:

The Lancet. "Collapse Of Teenage Clubber Highlights Dangers Of New Drug." ScienceDaily. ScienceDaily, 29 April 2007. <www.sciencedaily.com/releases/2007/04/070427104654.htm>.
The Lancet. (2007, April 29). Collapse Of Teenage Clubber Highlights Dangers Of New Drug. ScienceDaily. Retrieved October 24, 2014 from www.sciencedaily.com/releases/2007/04/070427104654.htm
The Lancet. "Collapse Of Teenage Clubber Highlights Dangers Of New Drug." ScienceDaily. www.sciencedaily.com/releases/2007/04/070427104654.htm (accessed October 24, 2014).

Share This



More Health & Medicine News

Friday, October 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

IKEA Desk Converts From Standing to Sitting With One Button

IKEA Desk Converts From Standing to Sitting With One Button

Buzz60 (Oct. 24, 2014) IKEA is out with a new convertible desk that can convert from a sitting desk to a standing one with just the push of a button. Jen Markham explains. Video provided by Buzz60
Powered by NewsLook.com
Ebola Protective Suits Being Made in China

Ebola Protective Suits Being Made in China

AFP (Oct. 24, 2014) A factory in China is busy making Ebola protective suits for healthcare workers and others fighting the spread of the virus. Duration: 00:38 Video provided by AFP
Powered by NewsLook.com
WHO: Millions of Ebola Vaccine Doses by 2015

WHO: Millions of Ebola Vaccine Doses by 2015

AP (Oct. 24, 2014) The World Health Organization said on Friday that millions of doses of two experimental Ebola vaccines could be ready for use in 2015 and five more experimental vaccines would start being tested in March. (Oct. 24) Video provided by AP
Powered by NewsLook.com
Doctor in NYC Quarantined With Ebola

Doctor in NYC Quarantined With Ebola

AP (Oct. 24, 2014) An emergency room doctor who recently returned to the city after treating Ebola patients in West Africa has tested positive for the virus. He's quarantined in a hospital. (Oct. 24) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins