Featured Research

from universities, journals, and other organizations

Leading The Fight Against Food Poisoning

Date:
May 25, 2007
Source:
University of Nottingham
Summary:
Scientists are developing new weapons in the fight against food poisoning, in this case, for the control of Campylobacter -- the commonest cause of infectious bacterial intestinal disease in England and Wales. Campylobacters are found in poultry and other animals and cause millions of cases of food poisoning worldwide.

Microscopic fluorescent green Campylobacter cells on chicken skin.
Credit: Photo by Anna Bates; courtesy of USDA/Agricultural Research Service

University of Nottingham experts have joined forces with Canadian biotech company GangaGen Life Sciences Inc to develop new weapons in the fight against food poisoning.

Related Articles


They are engaging in a major research project to develop methods for the control of Campylobacter — the commonest cause of infectious bacterial intestinal disease in England and Wales, according to the Health Protection Agency. Campylobacters are found in poultry and other animals and cause millions of cases of food poisoning worldwide.

The researchers intend to develop bacteriophage-based treatments for the control of Campylobacter.

Bacteriophages — the term literally means 'bacterium-eater' — are naturally occurring agents that target and destroy bacteria with a high degree of efficiency, and do so selectively and specifically, without affecting beneficial bacteria or gut cells. The term is commonly used in its shortened form, phage.

Both GangaGen and The University of Nottingham are leaders in bacteriophage research and view the technology as a vital breakthrough in the control of bacterial contamination and associated health risks. The research agreement, announced May 22 will mean they pool their resources for at least three years to develop new treatments.

Ian Connerton, Northern Foods Professor of Food Safety at The University of Nottingham, said: “We are excited to be working with a company like GangaGen that is at the forefront of phage technology development.

“Our team's research has demonstrated that certain phages specific for Campylobacter can significantly reduce the load of the bacteria carried by poultry. By implication, this should also reduce the risk to consumers by decreasing bacterial contamination of meat that is prevalent in poultry processing and is transferred to chicken meat on grocery shelves.”

GangaGen and The University of Nottingham are building a business relationship to commercialise phage technology which has been developed at the University to complement the existing phage expertise of GangaGen. This is part of the University's programme to transfer technology from academia into the commercial world.

Campylobacter infection is typically characterised by severe diarrhoea and abdominal pain, stomach cramps, fever and vomiting. Undercooked meat, particularly poultry, is often associated with the illness, and it is impossible to tell from its appearance whether it is contaminated — as it looks, tastes and smells normal.

GangaGen is a developer of therapeutics based on phage technology for the control of disease-causing bacteria. The company is developing a portfolio of products for the effective treatment of infectious disease in human and animal health. Its animal health program includes innovations for the control of food-safety hazards associated with the transfer of pathogenic bacteria from animal production to consumers.

The work on a phage product for the control of Campylobacter will complement GangaGen's food safety product portfolio, which also includes phage products against Salmonella and E. coli O157:H7.

Dr Rainer Engelhardt, Chief Executive of GangaGen Life Sciences Inc, said: “GangaGen believes that the place to start fighting food safety-related bacteria is at the farm where livestock production takes place, and this research agreement with The University of Nottingham allows us to continue building on that belief.

“The food industry and its regulators have stated that they believe that timely intervention is needed at the farm level to supplement the extensive, but not fully effective, controls already in place in food processing. GangaGen has demonstrated in production animal trials that we can isolate and use phages with full regard for safety, and that are benign to animals, humans and the environment.

“This research agreement is of great importance to the health market in general. The combination of these two research teams provides strong impetus for creating a safe, effective and low-cost solution to this pernicious consumer health risk.”

Food-safety authorities in Europe and in North America recently released data showing that the contamination hazard due to Campylobacter remains high, and may be increasing because the pathogen has also started to demonstrate resistance to several common antibiotics.


Story Source:

The above story is based on materials provided by University of Nottingham. Note: Materials may be edited for content and length.


Cite This Page:

University of Nottingham. "Leading The Fight Against Food Poisoning." ScienceDaily. ScienceDaily, 25 May 2007. <www.sciencedaily.com/releases/2007/05/070523113544.htm>.
University of Nottingham. (2007, May 25). Leading The Fight Against Food Poisoning. ScienceDaily. Retrieved November 27, 2014 from www.sciencedaily.com/releases/2007/05/070523113544.htm
University of Nottingham. "Leading The Fight Against Food Poisoning." ScienceDaily. www.sciencedaily.com/releases/2007/05/070523113544.htm (accessed November 27, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, November 27, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Experimental Ebola Vaccine Shows Promise In Human Trial

Experimental Ebola Vaccine Shows Promise In Human Trial

Newsy (Nov. 27, 2014) — A recent test of a prototype Ebola vaccine generated an immune response to the disease in subjects. Video provided by Newsy
Powered by NewsLook.com
Pet Dogs to Be Used in Anti-Ageing Trial

Pet Dogs to Be Used in Anti-Ageing Trial

Reuters - Innovations Video Online (Nov. 26, 2014) — Researchers in the United States are preparing to discover whether a drug commonly used in human organ transplants can extend the lifespan and health quality of pet dogs. Video provided by Reuters
Powered by NewsLook.com
Today's Prostheses Are More Capable Than Ever

Today's Prostheses Are More Capable Than Ever

Newsy (Nov. 26, 2014) — Advances in prosthetics are making replacement body parts stronger and more lifelike than they’ve ever been. Video provided by Newsy
Powered by NewsLook.com
From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

Newsy (Nov. 25, 2014) — The US FDA is announcing new calorie rules on Tuesday that will require everywhere from theaters to vending machines to include calorie counts. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins