Featured Research

from universities, journals, and other organizations

Hypothyroidism Clearly Linked To Mood Swings

Date:
June 6, 2007
Source:
Society of Nuclear Medicine
Summary:
Hypothyroidism is often associated with mood changes like depression lethargy. Researchers are studying underlying brain processes in search of "why" this happens.

Hypothyroidism is often associated with mood changes like depression lethargy. Researchers, studying underlying brain processes in search of "why" this happens, reported their results at the 54th Annual Meeting of SNM, the world's largest society for molecular imaging and nuclear medicine professionals.

Related Articles


"The aim of our study was to investigate--with positron emission tomography (PET) imaging--how physical health and mental health are interrelated," said Waltraud Eichhorn, a nuclear medicine physician at Johannes Gutenberg University in Mainz, Germany. "We found that hypothyroidism is correlated to regional metabolic changes in the thalamus--an area of the brain that helps process information from the senses and transmit it to other parts of the brain" she said. "In other words, hypothyroid patients--compared to healthy individuals--have decreased metabolism in special parts of the brain that are responsible for processing information, " said Eichhorn. "Remarkably, this reduction in metabolism remains detectable after thyroid hormone replacement therapy," she added.

The thyroid, a butterfly-shaped gland in the neck just above the collarbone, is an endocrine gland that makes hormones and helps set a body's metabolism (how the body gets energy from food). Hypothyroidism, a condition in which your body produces too little thyroid hormone, often leads to exhaustion and depression, affecting millions of Americans, many of them women or the elderly. There are 27 million Americans who have underactive or overactive thyroid glands, but more than half remain undiagnosed, according to recent statistics.

Hypothyroidism can be treated by doses of thyroid hormone. Once the blood levels of thyroid hormone reach a normal range--called euthyroid--lethargy and depression often lift. However, in some patients, the depression persists, which means that successful therapy must address depression directly.

In this study, 10 patients with hypothyroidism underwent a cerebral 18-FDG/PET examination. She indicated that additional research is needed to determine whether special brain regions are responsible for increased depression or anxiety in patients suffering from hypothyroidism.

PET is a safe, highly specialized, noninvasive imaging technique that uses short-lived radioactive substances to produce three-dimensional images of those substances functioning within the body. A special type of camera works with computers to provide precise pictures of the areas of the body being imaged and molecular images of the body's biological functions.

Scientific Poster 1228: W.A. Eichhorn, K. Bose, H. Buchholz, T. Siessmeier and M. Schreckenberger, Nuclear Medicine Department, and U. Egle, Department of Psychosomatic Medicine and Psychotherapy, all at Johannes Gutenberg University, Mainz, Germany; P. Bartenstein, Department of Nuclear Medicine, Ludwig Maximilians University, Muenchen, Germany; and G. Kahaly, Department of Medicine I, Johannes Gutenberg University, Mainz, Germany, "Neuronal Correlates of Overt Hypothyroidism Measured by FDG PET," SNM's 54th Annual Meeting, June 2--6, 2007.


Story Source:

The above story is based on materials provided by Society of Nuclear Medicine. Note: Materials may be edited for content and length.


Cite This Page:

Society of Nuclear Medicine. "Hypothyroidism Clearly Linked To Mood Swings." ScienceDaily. ScienceDaily, 6 June 2007. <www.sciencedaily.com/releases/2007/06/070604170803.htm>.
Society of Nuclear Medicine. (2007, June 6). Hypothyroidism Clearly Linked To Mood Swings. ScienceDaily. Retrieved March 30, 2015 from www.sciencedaily.com/releases/2007/06/070604170803.htm
Society of Nuclear Medicine. "Hypothyroidism Clearly Linked To Mood Swings." ScienceDaily. www.sciencedaily.com/releases/2007/06/070604170803.htm (accessed March 30, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, March 30, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

S. Leone in New Anti-Ebola Lockdown

S. Leone in New Anti-Ebola Lockdown

AFP (Mar. 28, 2015) Sierra Leone imposed a three-day nationwide lockdown Friday for the second time in six months in a bid to prevent a resurgence of the deadly Ebola virus. Duration: 01:17 Video provided by AFP
Powered by NewsLook.com
These Popular Antibiotics Can Cause Permanent Nerve Damage

These Popular Antibiotics Can Cause Permanent Nerve Damage

Newsy (Mar. 27, 2015) A popular class of antibiotic can leave patients in severe pain and even result in permanent nerve damage. Video provided by Newsy
Powered by NewsLook.com
WH Plan to Fight Antibiotic-Resistant Germs

WH Plan to Fight Antibiotic-Resistant Germs

AP (Mar. 27, 2015) The White House on Friday announced a five-year plan to fight the threat posed by antibiotic-resistant bacteria amid fears that once-treatable germs could become deadly. (March 27) Video provided by AP
Powered by NewsLook.com
House Ready to Pass Medicare Doc Bill

House Ready to Pass Medicare Doc Bill

AP (Mar. 26, 2015) In rare bipartisan harmony, congressional leaders pushed a $214 billion bill permanently blocking physician Medicare cuts toward House passage Thursday, moving lawmakers closer to resolving a problem that has plagued them for years. (March 26) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins