Featured Research

from universities, journals, and other organizations

Combating Infectious Disease With Probiotics

Date:
June 20, 2007
Source:
University College Cork
Summary:
Scientists have discovered that probiotic bacteria can protect against bacterial infection. The research group examined a range of beneficial bacteria and found one specific probiotic bacterium which was able to kill Listeria monocytogenes, an often lethal pathogen in pregnant women.

Scientists at University College Cork have discovered that probiotic bacteria can protect against bacterial infection.

The APC, funded by Science Foundation Ireland, was set up investigate the beneficial roles of the bacteria found in the gastro-intestine of healthy humans. The research group examined a range of beneficial bacteria and found one specific probiotic bacterium (Lactobacillus salivarius UCC118) which was able to kill Listeria monocytogenes, an often lethal pathogen in pregnant women. The probiotic kills the pathogen by producing an antibiotic-like compound called a bacteriocin.

Tests showed that Lactobacillus salivarius offered significant protection against Listeria infection but that a strain of non-bacteriocin producing Lactobacillus generated by the researchers did not. The results of the UCC work clearly demonstrate a role for bacteriocins in protecting the host against potentially lethal infections. The study is the first to clearly demonstrate a mechanism by which probiotic bacteria may act to help improve the health of consumers.

The results may prove to be very significant, in that Listeria monocytogenes is particularly dangerous during pregnancy, and in a number of other high risk groups, but is too rare to warrant vaccination or preventative antibiotic therapy. A probiotic taken during pregnancy could well provide protection against Listeria infection in a form which would be acceptable to expectant mothers.

The study was primarily conducted by Sinead Corr as part of her research towards her PhD, but also involved key contributions from other APC scientists Yin Li and Christian Riedel. The research was supervised by APC Principal Investigators Colin Hill, Cormac Gahan and Paul O’Toole from the Department of Microbiology and the School of Pharmacy, UCC..

Reference: Corr et al., (2007) Proceeding National Academy Science USA May 1 2007 vol 104 no. 18 , 7617-7621 "Bacteriocin production as a mechanism for the antiinfective activity of Lactobacillus salivarius" UCC118


Story Source:

The above story is based on materials provided by University College Cork. Note: Materials may be edited for content and length.


Cite This Page:

University College Cork. "Combating Infectious Disease With Probiotics." ScienceDaily. ScienceDaily, 20 June 2007. <www.sciencedaily.com/releases/2007/06/070619181022.htm>.
University College Cork. (2007, June 20). Combating Infectious Disease With Probiotics. ScienceDaily. Retrieved October 23, 2014 from www.sciencedaily.com/releases/2007/06/070619181022.htm
University College Cork. "Combating Infectious Disease With Probiotics." ScienceDaily. www.sciencedaily.com/releases/2007/06/070619181022.htm (accessed October 23, 2014).

Share This



More Plants & Animals News

Thursday, October 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Working Mother DIY: Pumpkin Pom-Pom

Working Mother DIY: Pumpkin Pom-Pom

Working Mother (Oct. 22, 2014) How to make a pumpkin pom-pom. Video provided by Working Mother
Powered by NewsLook.com
San Diego Zoo's White Rhinos Provide Hope for the Critically Endangered Species

San Diego Zoo's White Rhinos Provide Hope for the Critically Endangered Species

Reuters - Light News Video Online (Oct. 22, 2014) The pair of rare white northern rhinos bring hope for their species as only six remain in the world. Elly Park reports. Video provided by Reuters
Powered by NewsLook.com
Raw: Bear Cub Strolls Through Oregon Drug Store

Raw: Bear Cub Strolls Through Oregon Drug Store

AP (Oct. 22, 2014) Shoppers at an Oregon drug store were surprised by a bear cub scurrying down the aisles this past weekend. (Oct. 22) Video provided by AP
Powered by NewsLook.com
Family Pleads for Pet Pig to Stay at Home

Family Pleads for Pet Pig to Stay at Home

AP (Oct. 22, 2014) The Johnson family lost their battle with the Chesterfield County, Virginia Planning Commission to allow Tucker, their pet pig, to stay in their home, but refuse to let the board keep Tucker away. (Oct. 22) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins