Featured Research

from universities, journals, and other organizations

Computerized Cervical Cancer Test Increases Detection Rate Of Abnormal Cells

Date:
July 4, 2007
Source:
BMJ-British Medical Journal
Summary:
A new computerized screening test for cervical cancer detects more abnormalities than the traditional smear test, according to a study published online.

A new computerised screening test for cervical cancer detects more abnormalities than the traditional smear test, according to a study published on bmj.com today.

Related Articles


It could also lead to fewer women needing to be re-tested and might allow for longer intervals in-between testing, says Elizabeth Davey and her colleagues.

The manual screening of conventional pap smears for cervical cancer has been around for decades but liquid-based cytology (LBC) is now replacing it in many countries.

Conventional smears are made by transferring material, taken from the cervix by a collection instrument, directly onto a glass slide. LBC slides are made by rinsing the collection instrument in liquid to produce a suspension, which is processed in a laboratory to produce a single layer of cells.

A recent study published by Guglielmo Ronco in the BMJ found that LBC did not significantly increase the ability to detect moderate (CIN2) or severe abnormalities (CIN3) compared to the conventional smear when both slides were evaluated manually by a cytologist.

In the study published today by Dr Davey, researchers used a computerised reading system, known as a Thin Prep Imager (TPI) to evaluate LBC slides. The programme would highlight any slides which needed further examination. These were looked at by a cytologist.

Samples were taken from 55,164 Australian women. From each single collection, a conventional cytology (CC) sample was made first, followed by a TPI sample.

The most important finding of the study is that the ThinPrep Imager detected 1.3 more cases of high-grade cervical abnormalities per 1,000 women screened than the conventional cytology test.

In Australia, 7.7 cases per 1,000 women screened are currently detected each year through a biennial Pap test screening programme using conventional cytology. Based on the results of this study, introducing the ThinPrep Imager would increase detection to 9.0 cases per 1,000 women screened.

Furthermore, fewer slides were found to be unsatisfactory using TPI -- 1.78% compared to 3.09% with CC. Therefore, fewer women might be recalled for repeat smears than currently occurs if the ThinPrep Imager were introduced into population screening programmes.

The use of the TPI also increased detection of low-grade cell lesions and the researchers conclude this could result in higher rates of further testing. On the other hand, they say, together with the finding of improved detection of moderate and severe changes (CIN2 and CIN3), it does raise the possibility that the increased detection of abnormalities by TPI might allow longer intervals in between screening.


Story Source:

The above story is based on materials provided by BMJ-British Medical Journal. Note: Materials may be edited for content and length.


Cite This Page:

BMJ-British Medical Journal. "Computerized Cervical Cancer Test Increases Detection Rate Of Abnormal Cells." ScienceDaily. ScienceDaily, 4 July 2007. <www.sciencedaily.com/releases/2007/07/070702145344.htm>.
BMJ-British Medical Journal. (2007, July 4). Computerized Cervical Cancer Test Increases Detection Rate Of Abnormal Cells. ScienceDaily. Retrieved March 27, 2015 from www.sciencedaily.com/releases/2007/07/070702145344.htm
BMJ-British Medical Journal. "Computerized Cervical Cancer Test Increases Detection Rate Of Abnormal Cells." ScienceDaily. www.sciencedaily.com/releases/2007/07/070702145344.htm (accessed March 27, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, March 27, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

These Popular Antibiotics Can Cause Permanent Nerve Damage

These Popular Antibiotics Can Cause Permanent Nerve Damage

Newsy (Mar. 27, 2015) — A popular class of antibiotic can leave patients in severe pain and even result in permanent nerve damage. Video provided by Newsy
Powered by NewsLook.com
House Ready to Pass Medicare Doc Bill

House Ready to Pass Medicare Doc Bill

AP (Mar. 26, 2015) — In rare bipartisan harmony, congressional leaders pushed a $214 billion bill permanently blocking physician Medicare cuts toward House passage Thursday, moving lawmakers closer to resolving a problem that has plagued them for years. (March 26) Video provided by AP
Powered by NewsLook.com
What's Different About This Latest Ebola Vaccine

What's Different About This Latest Ebola Vaccine

Newsy (Mar. 26, 2015) — A whole virus Ebola vaccine has been shown to protect monkeys exposed to the virus. Here&apos;s what&apos;s different about this vaccine. Video provided by Newsy
Powered by NewsLook.com
HIV Outbreak Prompts Public Health Emergency In Indiana

HIV Outbreak Prompts Public Health Emergency In Indiana

Newsy (Mar. 26, 2015) — Indiana Gov. Mike Pence says he will bring additional state resources to help stop the epidemic. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins