Featured Research

from universities, journals, and other organizations

Complex ART Procedures More Likely To Lead To Umbilical Cord Abnormality

Date:
July 9, 2007
Source:
European Society for Human Reproduction and Embryology
Summary:
The more complex the assisted reproduction procedure, the more likely the umbilical cord develops in an atypical place or have other abnormalities, a scientist told the 23rd Annual Conference of the European Society of Human Reproduction and Embryology. Mrs. Ilse Delbaere, from Ghent University Hospital, Ghent, Belgium, said that the study, including over 4000 twin pregnancies, was the first to examine umbilical cord abnormalities in such a large population.

The more complex the assisted reproduction procedure, the more likely the umbilical cord develops in an atypical place or have other abnormalities, a scientist told the 23rd annual conference of the European Society of Human Reproduction and Embryology (Wednesday 4 July). Mrs. Ilse Delbaere, from Ghent University Hospital, Ghent, Belgium, said that the study, including over 4000 twin pregnancies, was the first to examine umbilical cord abnormalities in such a large population.

For many years, scientists have known that both singletons and twins conceived after fertility treatment do worse in terms of duration of pregnancy and in live birth weight. "Certain umbilical cord pathologies, such as the insertion of the cord on the placental membranes instead of centrally in the placenta, or the absence of one artery in the cord, are known to correlate with an adverse outcome", said Mrs Delbaere, "and we wanted to find out whether these cord anomalies were more frequent after assisted reproduction."

The team studied data from the East Flanders Prospective Twin Survey (EFPTS), containing information on all multiple births in the region since 1964. "Since assisted reproduction was rather rare until the mid-eighties", said Mrs. Delbaere, "we analysed twins born between 1985 and 2004." The scientists compared cord characteristics from 2119 spontaneously conceived dizygotic (non-identical) twins and 2243 dizygotic twins who had been born as a result of assisted reproduction technologies (ART). Sub analyses looked at the different types of ART according to its 'invasiveness' and complexity.

The results showed not only that cord abnormalities occurred more frequently in ART twins, but that they varied according to the technique used.

"We found an incidence of velamentous insertion, where the cord attaches to the placental membrane, of 3.6% in spontaneously conceived twins," said Mrs. Delbaere. "But in twins conceived after IVF we found an incidence of 7.4%, and after intracytoplasmatic sperm injection (ICSI), where a single sperm is injected into an egg, it was 10.4%."

The scientists think that embryo implantation may be different after assisted reproduction. When an embryo is transferred to an area with poorer nourishment conditions, the placenta may migrate to more favourable areas, turning an initial central insertion of the cord into something more peripheral.

"We intend to follow up this work by studying whether the birth weight of twins born after ART is still lower when we exclude twins with umbilical cord pathology", said Mrs Delbaere. "We believe that this will be the first time that these two issues have been teased out in this way. We hope that our work will contribute to the understanding of how the placenta and cord develop early in pregnancy."


Story Source:

The above story is based on materials provided by European Society for Human Reproduction and Embryology. Note: Materials may be edited for content and length.


Cite This Page:

European Society for Human Reproduction and Embryology. "Complex ART Procedures More Likely To Lead To Umbilical Cord Abnormality." ScienceDaily. ScienceDaily, 9 July 2007. <www.sciencedaily.com/releases/2007/07/070704144524.htm>.
European Society for Human Reproduction and Embryology. (2007, July 9). Complex ART Procedures More Likely To Lead To Umbilical Cord Abnormality. ScienceDaily. Retrieved April 23, 2014 from www.sciencedaily.com/releases/2007/07/070704144524.htm
European Society for Human Reproduction and Embryology. "Complex ART Procedures More Likely To Lead To Umbilical Cord Abnormality." ScienceDaily. www.sciencedaily.com/releases/2007/07/070704144524.htm (accessed April 23, 2014).

Share This



More Health & Medicine News

Wednesday, April 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Big Pharma Braces for M&A Wave

Big Pharma Braces for M&A Wave

Reuters - Business Video Online (Apr. 22, 2014) Big pharma on the move as Novartis boss, Joe Jimenez, tells Reuters about plans to transform his company via an asset exchange with GSK, and Astra Zeneca shares surge on speculation that Pfizer is looking for a takeover. Joanna Partridge reports. Video provided by Reuters
Powered by NewsLook.com
Study Says Most Crime Not Linked To Mental Illness

Study Says Most Crime Not Linked To Mental Illness

Newsy (Apr. 22, 2014) A new study finds most crimes committed by people with mental illness are not caused by symptoms of their illness or disorder. Video provided by Newsy
Powered by NewsLook.com
Hagel Gets Preview of New High-Tech Projects

Hagel Gets Preview of New High-Tech Projects

AP (Apr. 22, 2014) Defense Secretary Chuck Hagel is given hands-on demonstrations Tuesday of some of the newest research from DARPA _ the military's Defense Advanced Research Projects Agency program. (April 22) Video provided by AP
Powered by NewsLook.com
How Smaller Plates And Cutlery Could Make You Feel Fuller

How Smaller Plates And Cutlery Could Make You Feel Fuller

Newsy (Apr. 22, 2014) NBC's "Today" conducted an experiment to see if changing the size of plates and utensils affects the amount individuals eat. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins