Featured Research

from universities, journals, and other organizations

Mild Stress In The Womb May Worsen Risk Of Cerebral Palsy

Date:
July 12, 2007
Source:
Society for Neuroscience
Summary:
Chronic mild stress in pregnant mothers may increase the risk that their offspring will develop cerebral palsy -- a group of neurological disorders marked by physical disability -- according to new research in mice. The results may be the first to demonstrate such effects of stress on animals in the womb.

Chronic mild stress in pregnant mothers may increase the risk that their offspring will develop cerebral palsy--a group of neurological disorders marked by physical disability--according to new research in mice. The results may be the first to demonstrate such effects of stress on animals in the womb.

The new study, led by Pierre Gressens, MD, PhD, of Inserm in France, used a mouse model to test whether exposure to minimal but repeated stress throughout gestation would make the offspring more vulnerable to brain lesions similar to those observed in children with cerebral palsy. 

"These findings are consistent with growing evidence that constant stress, even minimal, can have a major impact on the quality of life," says Victoria Luine, PhD, distinguished professor of psychology at New York's Hunter College, who did not participate in the research.

In the study, the scientists adjusted the normal cycle of light and dark that the pregnant mice were accustomed to for half of the mice, subjecting them to a mild level of stress. Then the researchers exposed the brains of the developing fetuses to injury. When the brains of the young mice were examined on birth, Gressens and his team found that the offspring born from stressed mothers showed brain lesions about twice as big as those in offspring of unstressed mothers.

"Determining the impact of gestational stress on the incidence of cerebral palsy would be of paramount interest," says Gressens. "Limiting stress during human pregnancy might prove to be a cost-efficient way to reduce the human, emotional, social and economic burden of cerebral palsy."

The findings are published in the July 11 issue of The Journal of Neuroscience. Inserm, l'Institut national de la santé et de la recherche médicale, is the French public biomedical research agency.

The work was a supported by Inserm, the Centre National de la Recherche Scientifique, the Universités Paris 6 and 7, the Fondation Grace de Monaco, the association Société d'Etudes et de Soins pour les Enfants Paralysés et Polymalformés, the Assistance Publique-Hôpitaux de Paris, and the Académie Nationale de Médicine.


Story Source:

The above story is based on materials provided by Society for Neuroscience. Note: Materials may be edited for content and length.


Cite This Page:

Society for Neuroscience. "Mild Stress In The Womb May Worsen Risk Of Cerebral Palsy." ScienceDaily. ScienceDaily, 12 July 2007. <www.sciencedaily.com/releases/2007/07/070711105828.htm>.
Society for Neuroscience. (2007, July 12). Mild Stress In The Womb May Worsen Risk Of Cerebral Palsy. ScienceDaily. Retrieved September 22, 2014 from www.sciencedaily.com/releases/2007/07/070711105828.htm
Society for Neuroscience. "Mild Stress In The Womb May Worsen Risk Of Cerebral Palsy." ScienceDaily. www.sciencedaily.com/releases/2007/07/070711105828.htm (accessed September 22, 2014).

Share This



More Plants & Animals News

Monday, September 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Cat Lovers Flock to Los Angeles

Cat Lovers Flock to Los Angeles

AFP (Sep. 22, 2014) — The best funny internet cat videos are honoured at LA's Feline Film Festival. Duration: 00:56 Video provided by AFP
Powered by NewsLook.com
Raw: San Diego Zoo Welcomes Cheetah Cubs

Raw: San Diego Zoo Welcomes Cheetah Cubs

AP (Sep. 20, 2014) — The San Diego Zoo has welcomed two Cheetah cubs to its Safari Park. The nearly three-week-old female cubs are being hand fed and are receiving around the clock care. (Sept. 20) Video provided by AP
Powered by NewsLook.com
Chocolate Museum Opens in Brussels

Chocolate Museum Opens in Brussels

AFP (Sep. 19, 2014) — Considered a "national heritage" in Belgium, chocolate now has a new museum in Brussels. In a former chocolate factory, visitors to the permanent exhibition spaces, workshops and tastings can discover derivatives of the cocoa bean. Duration: 01:00 Video provided by AFP
Powered by NewsLook.com
Top 3 Outrageous Animal Stories Of The Week

Top 3 Outrageous Animal Stories Of The Week

Newsy (Sep. 19, 2014) — This week's animal stories include a goldfish having surgery, a pizza chain giving out pets, and a tiger found on the side of the road. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins