Featured Research

from universities, journals, and other organizations

Once-a-day Epilepsy Drug Is Effective For Partial Seizures, Study Suggests

Date:
October 17, 2007
Source:
American Academy of Neurology
Summary:
The epilepsy drug lamotrigine is effective in controlling partial seizures when taken once a day as an added therapy, according to a new study. The study involved 239 people from the United States and several other countries.

The epilepsy drug lamotrigine is effective in controlling partial seizures when taken once a day as an added therapy, according to a study published in the October 16, 2007, issue of Neurology®, the medical journal of the American Academy of Neurology.

"These results are important because maintaining stable blood levels of epilepsy drugs and good control of seizures depends on people taking their medications reliably and consistently," said study author Dean Naritoku, MD, of Southern Illinois University in Springfield and member of the American Academy of Neurology. "The more often people have to remember to take their medication each day, the more likely they are to miss a dose. Once-a-day dosing is more convenient for patients."

The study involved 239 people from the United States and several other countries. Participants were age 13 and older with partial seizures not fully controlled by medication. Some of the participants also had secondary generalized seizures. The participants were already taking one to two epilepsy medications; lamotrigine was added to their therapy. They received either lamotrigine in an extended-release formula or placebo for 19 weeks.

Those taking lamotrigine as an added therapy had 46 percent fewer partial seizures during the study, compared to 24 percent fewer for those taking a placebo. In addition, 42 percent of those taking lamotrigine as an added therapy reduced their seizure frequently by at least half by the end of the study, compared to 24 percent of those taking a placebo.

"This new once daily medication may be an important option for people with epilepsy that could significantly increase their compliance with prescribed treatment," said Naritoku.

The most common side effects were headache, which was experienced by 17 percent of those taking lamotrigine and 15 percent of those taking placebo, and dizziness, which was experienced by 18 percent of those taking lamotrigine and five percent of those taking placebo.

The study was sponsored and conducted by GlaxoSmithKline.


Story Source:

The above story is based on materials provided by American Academy of Neurology. Note: Materials may be edited for content and length.


Cite This Page:

American Academy of Neurology. "Once-a-day Epilepsy Drug Is Effective For Partial Seizures, Study Suggests." ScienceDaily. ScienceDaily, 17 October 2007. <www.sciencedaily.com/releases/2007/10/071015193529.htm>.
American Academy of Neurology. (2007, October 17). Once-a-day Epilepsy Drug Is Effective For Partial Seizures, Study Suggests. ScienceDaily. Retrieved September 17, 2014 from www.sciencedaily.com/releases/2007/10/071015193529.htm
American Academy of Neurology. "Once-a-day Epilepsy Drug Is Effective For Partial Seizures, Study Suggests." ScienceDaily. www.sciencedaily.com/releases/2007/10/071015193529.htm (accessed September 17, 2014).

Share This



More Health & Medicine News

Wednesday, September 17, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Obesity Rates Steady Even As Americans' Waistlines Expand

Obesity Rates Steady Even As Americans' Waistlines Expand

Newsy (Sep. 17, 2014) — Researchers are puzzled as to why obesity rates remain relatively stable as average waistlines continue to expand. Video provided by Newsy
Powered by NewsLook.com
President To Send 3,000 Military Personnel To Fight Ebola

President To Send 3,000 Military Personnel To Fight Ebola

Newsy (Sep. 16, 2014) — President Obama is expected to send 3,000 troops to West Africa as part of the effort to contain Ebola's spread. Video provided by Newsy
Powered by NewsLook.com
Obama Orders Military Response to Ebola

Obama Orders Military Response to Ebola

AP (Sep. 16, 2014) — Calling the Ebola outbreak in West Africa a potential threat to global security, President Barack Obama is ordering 3,000 U.S. military personnel to the stricken region amid worries that the outbreak is spiraling out of control. (Sept. 16) Video provided by AP
Powered by NewsLook.com
UN: 20,000 Could Be Infected With Ebola by Year End

UN: 20,000 Could Be Infected With Ebola by Year End

AFP (Sep. 16, 2014) — Nearly $1.0 billion dollars is needed to fight the Ebola outbreak raging in west Africa, the United Nations say, warning that 20,000 could be infected by year end. Duration: 00:40 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins