Featured Research

from universities, journals, and other organizations

Subcutaneous Administration Of An Antiemetic For Treating Vomiting Caused By Chemotherapy

Date:
November 16, 2007
Source:
Basque Research
Summary:
The subcutaneous administration of granisetron, an antiemetic pharmaceutical drug (suitable for control of vomiting), achieves similar blood concentrations to those administered intravenously. This was the conclusion of clinical tests.

The subcutaneous administration of granisetron, an antiemetic pharmaceutical drug (suitable for control of vomiting), achieves similar blood concentrations to those administered intravenously. This was the conclusion of clinical tests undertaken by specialists at the University Hospital of Navarra.

Related Articles


Granisetrσn is a pharmaceutical drug the efficacy of which against vomiting (antiemetic), when administered orally or intravenously, has already been shown, but never studied when given subcutaneously. The research shows that the antiemetic granisetron, administered subcutaneously, behaves in a similar manner as when injected intravenously. The advantage of the subcutaneous method is the ease of treatment for non-hospitalised patients. For these patients using the intravenous method it is problematic, requiring, as it does, specialised care; while administering orally may involve the patient vomiting.

Home use and emergencies

This is why subcutaneous administration opens new perspectives, providing a comfortable and easy way of home-based treatment, either with self-medication by the patients themselves or administered by their carers, in either case reducing the dependence on trained medical personnel.

The fundamental objective of the work undertaken was, thereby, to demonstrate if it were feasible for the patients themselves to manage to self-medicate the antiemetic in their own homes in case of vomiting as a consequence of chemotherapy treatment. In this way, the patient does not have to go to a hospital in order to control nauseas and vomiting. Nevertheless, this form of medication is also useful for healthcare personnel such as the emergency services.

Trials

A total of 30 patients participated in the trial. All were medicated with granisetron, using one of the two forms of administration, intravenous or subcutaneous, during the first cycle of chemotherapy and, in the following cycle, the other alternative was employed. Then a number of blood samples of all the patients were obtained in order to determine the concentration of the pharmaceutical drug in each sample.

The conclusions of the study confirm that the concentrations of granisetron obtained were equivalent in both methods of medication. This is why the research supports the administration of granisetron subcutaneously as a new alternative for the treatment of cancer patients.

The results of this study have been recently published in the medical journal, The Oncologist.


Story Source:

The above story is based on materials provided by Basque Research. Note: Materials may be edited for content and length.


Cite This Page:

Basque Research. "Subcutaneous Administration Of An Antiemetic For Treating Vomiting Caused By Chemotherapy." ScienceDaily. ScienceDaily, 16 November 2007. <www.sciencedaily.com/releases/2007/11/071116094819.htm>.
Basque Research. (2007, November 16). Subcutaneous Administration Of An Antiemetic For Treating Vomiting Caused By Chemotherapy. ScienceDaily. Retrieved November 24, 2014 from www.sciencedaily.com/releases/2007/11/071116094819.htm
Basque Research. "Subcutaneous Administration Of An Antiemetic For Treating Vomiting Caused By Chemotherapy." ScienceDaily. www.sciencedaily.com/releases/2007/11/071116094819.htm (accessed November 24, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, November 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Winter Can Cause Depression — Here's How To Combat It

Winter Can Cause Depression — Here's How To Combat It

Newsy (Nov. 23, 2014) — Millions of American suffer from seasonal depression every year. It can lead to adverse health effects, but there are ways to ease symptoms. Video provided by Newsy
Powered by NewsLook.com
Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

AFP (Nov. 23, 2014) — The arable district of Kenema in Sierra Leone -- at the centre of the Ebola outbreak in May -- has been under quarantine for three months as the cocoa harvest comes in. Duration: 01:32 Video provided by AFP
Powered by NewsLook.com
Don't Fall For Flu Shot Myths

Don't Fall For Flu Shot Myths

Newsy (Nov. 23, 2014) — Misconceptions abound when it comes to your annual flu shot. Medical experts say most people older than 6 months should get the shot. Video provided by Newsy
Powered by NewsLook.com
Indians Muck in for Cleaner Communities

Indians Muck in for Cleaner Communities

AFP (Nov. 22, 2014) — India's government is urging all citizens to come together in a mass movement to clean the nation -- but will people heed the call? Duration: 02:39 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins