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High Carb Diet Linked to Prostate Tumor Growth

Date:
November 28, 2007
Source:
Journal of the National Cancer Institute
Summary:
A diet high in refined carbohydrates, like white rice or white bread, is associated with increased prostate tumor growth in mice. Having too much insulin in the blood, a condition called hyperinsulinemia, is associated with poorer outcomes in patients with prostate cancer. Scientists investigated whether high insulin levels caused by eating a diet high in refined carbohydrates would lead to more rapid growth of prostate tumors in mice.

A diet high in refined carbohydrates, like white rice or white bread, is associated with increased prostate tumor growth in mice.

Having too much insulin in the blood, a condition called hyperinsulinemia, is associated with poorer outcomes in patients with prostate cancer. Vasundara Venkateswaran, Ph.D., of Sunnybrook Health Sciences Centre in Toronto and colleagues investigated whether high insulin levels caused by eating a diet high in refined carbohydrates would lead to more rapid growth of prostate tumors in mice.

Forty mice were randomly assigned to either a high carbohydrate-high fat diet or a low carbohydrate-high fat one for nine weeks. The researchers measured the animals' weight, tumor size, and insulin levels weekly. Mice on the high carbohydrate diet gained more weight, had faster growing tumors, and had higher insulin levels than mice on the low carbohydrate diet.

"Our results provide support for the concept that diets associated with a reduction in insulin level may have benefits for prostate cancer patients, particularly for the subset of patients who are hyperinsulinemic," the authors write.


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The above story is based on materials provided by Journal of the National Cancer Institute. Note: Materials may be edited for content and length.


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Journal of the National Cancer Institute. "High Carb Diet Linked to Prostate Tumor Growth." ScienceDaily. ScienceDaily, 28 November 2007. <www.sciencedaily.com/releases/2007/11/071127161824.htm>.
Journal of the National Cancer Institute. (2007, November 28). High Carb Diet Linked to Prostate Tumor Growth. ScienceDaily. Retrieved September 30, 2014 from www.sciencedaily.com/releases/2007/11/071127161824.htm
Journal of the National Cancer Institute. "High Carb Diet Linked to Prostate Tumor Growth." ScienceDaily. www.sciencedaily.com/releases/2007/11/071127161824.htm (accessed September 30, 2014).

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