Featured Research

from universities, journals, and other organizations

Allergic-like Reactions Can Occur In Premedicated Patients

Date:
February 8, 2008
Source:
American Roentgen Ray Society
Summary:
Allergic-like reactions can occur in patients (both children and adults) when given gadolinium containing contrast agents, even if they have been pre-medicated with corticosteroids and antihistamines, according to a recent study.

Allergic-like reactions can occur in patients (both children and adults) when given gadolinium containing contrast agents, even if they have been pre-medicated with corticosteroids and antihistamines, according to a recent study conducted by researchers at the University of Michigan Health Systems in Ann Arbor.

"We pre-medicate patients at our institution who have a history of prior allergic-like reaction to gadolinium-containing contrast agents", said Jonathan R. Dillman, MD, lead author of the study.

"Pre-medication is sometimes also considered in patients who have a history of prior severe allergic-like reaction to another substance (including iodinated contrast material)," said Dr. Dillman. "While we know from previous studies that allergic-like reactions may occur following pre-medication in the setting of repeat iodinated contrast material injections (the so-called 'breakthrough reaction'), we were uncertain if this phenomenon also occurred in the setting of repeat gadolinium-containing contrast material administration," he said.

The researchers reviewed contrast material reaction forms from the institution's department of radiology over a five-year period. According to the study, eight patients experienced nine allergic-like reactions (one patient experienced two breakthrough reactions) after being administered a gadolinium-containing contrast agent despite being pre-medicated.

Of these reactions, six were mild and three were moderate. There were no severe or fatal breakthrough reactions. All patients who experienced breakthrough reactions had a history of allergic-like reactions to either gadolinium or iodine containing contrast media.

"While we believe that pre-medication likely decreases an individual's risk of allergic-like reaction to gadolinium-containing contrast material, our study concludes that 'breakthrough reactions' do occur. Radiologists, therefore, must be available to treat an allergic-like reaction following gadolinium-containing contrast material administration, even when a patient has been pre-medicated with corticosteroids and antihistamines," said Dr. Dillman.

The full results of this study appear in a recent issue of the American Journal of Roentgenology.


Story Source:

The above story is based on materials provided by American Roentgen Ray Society. Note: Materials may be edited for content and length.


Cite This Page:

American Roentgen Ray Society. "Allergic-like Reactions Can Occur In Premedicated Patients." ScienceDaily. ScienceDaily, 8 February 2008. <www.sciencedaily.com/releases/2008/02/080208160626.htm>.
American Roentgen Ray Society. (2008, February 8). Allergic-like Reactions Can Occur In Premedicated Patients. ScienceDaily. Retrieved July 26, 2014 from www.sciencedaily.com/releases/2008/02/080208160626.htm
American Roentgen Ray Society. "Allergic-like Reactions Can Occur In Premedicated Patients." ScienceDaily. www.sciencedaily.com/releases/2008/02/080208160626.htm (accessed July 26, 2014).

Share This




More Health & Medicine News

Saturday, July 26, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Beatings and Addiction: Pakistan Drug 'clinic' Tortures Patients

Beatings and Addiction: Pakistan Drug 'clinic' Tortures Patients

AFP (July 24, 2014) A so-called drugs rehab 'clinic' is closed down in Pakistan after police find scores of ‘patients’ chained up alleging serial abuse. Duration 03:05 Video provided by AFP
Powered by NewsLook.com
Too Few Teens Receiving HPV Vaccination, CDC Says

Too Few Teens Receiving HPV Vaccination, CDC Says

Newsy (July 24, 2014) The Centers for Disease Control and Prevention is blaming doctors for the low number of children being vaccinated for HPV. Video provided by Newsy
Powered by NewsLook.com
New Painkiller Designed To Discourage Abuse: Will It Work?

New Painkiller Designed To Discourage Abuse: Will It Work?

Newsy (July 24, 2014) The FDA approved Targiniq ER on Wednesday, a painkiller designed to keep users from abusing it. Like any new medication, however, it has doubters. Video provided by Newsy
Powered by NewsLook.com
Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Newsy (July 24, 2014) Sheik Umar Khan has treated many of the people infected in the Ebola outbreak, and now he's become one of them. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins