Featured Research

from universities, journals, and other organizations

Breast Feeding May Help Protect Babies Against Allergic Asthma

Date:
February 25, 2008
Source:
Nature Medicine
Summary:
Breast feeding may help protect babies against allergic asthma. Airborne allergen is able to pass from mother to child through breast milk, which creates a tolerance to the allergen. Allergic asthma affects 300 million people worldwide and is characterized by obstruction of the respiratory pathways in response to allergen exposure.

Breast feeding may help protect babies against allergic asthma. Airborne allergen is able to pass from mother to child through breast milk, which creates a tolerance to the allergen.

Allergic asthma affects 300 million people worldwide and is characterized by obstruction of the respiratory pathways in response to allergen exposure. Its prevalence has increased in recent decades, probably due to changes in environmental factors. Indeed, exposure to environmental antigens during infancy reduces the likelihood of developing asthma.

Valerie Julia and her colleagues investigated whether exposing lactating mice to an airborne allergen — ovalbumin — affected asthma development in the offspring. They found that ovalbumin was efficiently transferred from the mother to the neonate through the milk, leading to the development of immunological tolerance. Tolerance induction relied on the presence of transforming growth factor–beta and was mediated by regulatory CD4+ T lymphocytes, but did not require the transfer of immunoglobulins through the milk.

Breast milk–mediated transfer of an antigen to the neonate can result in oral tolerance induction, leading to antigen-specific protection from allergic asthma. These observations may pave the way for the design of new strategies to prevent the development of allergic diseases.

Journal reference: Valérie Verhasselt, Valérie Milcent, Julie Cazareth, Akira Kanda, Sébastien Fleury, David Dombrowicz, Nicolas Glaichenhaus & Valérie Julia. Breast milk–mediated transfer of an antigen induces tolerance and protection from allergic asthma pp 170 - 175. Published online Nature Medicine. 27 January 2008. doi 10.1038/nm1718


Story Source:

The above story is based on materials provided by Nature Medicine. Note: Materials may be edited for content and length.


Cite This Page:

Nature Medicine. "Breast Feeding May Help Protect Babies Against Allergic Asthma." ScienceDaily. ScienceDaily, 25 February 2008. <www.sciencedaily.com/releases/2008/02/080224142005.htm>.
Nature Medicine. (2008, February 25). Breast Feeding May Help Protect Babies Against Allergic Asthma. ScienceDaily. Retrieved August 30, 2014 from www.sciencedaily.com/releases/2008/02/080224142005.htm
Nature Medicine. "Breast Feeding May Help Protect Babies Against Allergic Asthma." ScienceDaily. www.sciencedaily.com/releases/2008/02/080224142005.htm (accessed August 30, 2014).

Share This




More Health & Medicine News

Saturday, August 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

3 Things To Know About The Ebola Outbreak's Progression

3 Things To Know About The Ebola Outbreak's Progression

Newsy (Aug. 29, 2014) — Here are three things you need to know about the deadly Ebola outbreak's progression this week. Video provided by Newsy
Powered by NewsLook.com
Killer Amoeba Found in Louisiana Water System

Killer Amoeba Found in Louisiana Water System

AP (Aug. 28, 2014) — State health officials say testing has confirmed the presence of a killer amoeba in a water system serving three St. John the Baptist Parish towns. (Aug. 28) Video provided by AP
Powered by NewsLook.com
Who Could Be Burnt by WHO's E-Cigs Move?

Who Could Be Burnt by WHO's E-Cigs Move?

Reuters - Business Video Online (Aug. 28, 2014) — The World Health Organisation has called for the regulation of electronic cigarettes as both tobacco and medical products. Ciara Lee looks at the impact of the move on the tobacco industry. Video provided by Reuters
Powered by NewsLook.com
CDC Director On Ebola Outbreak: 'It's Worse Than I Feared'

CDC Director On Ebola Outbreak: 'It's Worse Than I Feared'

Newsy (Aug. 28, 2014) — CDC director Tom Frieden says the Ebola outbreak is even worse than he feared. But he also said there's still hope to contain it. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins