Featured Research

from universities, journals, and other organizations

Understanding Our Saliva

Date:
March 10, 2008
Source:
American Society for Biochemistry and Molecular Biology
Summary:
Researchers have developed a novel technique to separate and analyze all the proteins found in human saliva, not just the soluble ones, providing an approach that may reveal protein markers for oral cancer and other disorders in the oral cavity.

Researchers have developed a novel technique to separate and analyze all the proteins found in human saliva, not just the soluble ones, providing an approach that may reveal protein markers for oral cancer and other disorders in the oral cavity.

Saliva contains an abundance of proteins that could be used to screen for diseases, particularly oral diseases. Until now, though, studies have only focused on the small subset of free-floating saliva proteins. Far more proteins are present inside of oral cells, and Timothy Griffin, Nelson Rhodus and colleagues developed a method, called three-step peptide fractionation, to look at those understudied proteins.

They analyzed saliva samples from four oral cancer patients and identified over 1000 human proteins, including many known cancer associated proteins. In addition, they separated out proteins from over 30 different bacteria, many of which have not been previously found in saliva, and several of which may also have possible cancer links.

The researchers note that the mortality rate for oral cancer has hardly declined over the past 30 years; their technique, providing the first description of using whole cells to identify the vast array of human and bacterial proteins in saliva, may help identify new markers for oral cancer progression.

This research was recently published in the journal Molecular And Cellular Proteomics.


Story Source:

The above story is based on materials provided by American Society for Biochemistry and Molecular Biology. Note: Materials may be edited for content and length.


Cite This Page:

American Society for Biochemistry and Molecular Biology. "Understanding Our Saliva." ScienceDaily. ScienceDaily, 10 March 2008. <www.sciencedaily.com/releases/2008/03/080306155718.htm>.
American Society for Biochemistry and Molecular Biology. (2008, March 10). Understanding Our Saliva. ScienceDaily. Retrieved April 17, 2014 from www.sciencedaily.com/releases/2008/03/080306155718.htm
American Society for Biochemistry and Molecular Biology. "Understanding Our Saliva." ScienceDaily. www.sciencedaily.com/releases/2008/03/080306155718.htm (accessed April 17, 2014).

Share This



More Health & Medicine News

Thursday, April 17, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Could Even Casual Marijuana Use Alter Your Brain?

Could Even Casual Marijuana Use Alter Your Brain?

Newsy (Apr. 16, 2014) A new study conducted by researchers at Northwestern and Harvard suggests even casual marijuana use can alter your brain. Video provided by Newsy
Powered by NewsLook.com
Thousands Of Vials Of SARS Virus Go Missing

Thousands Of Vials Of SARS Virus Go Missing

Newsy (Apr. 16, 2014) A research institute in Paris somehow misplaced more than 2,000 vials of the deadly SARS virus. Video provided by Newsy
Powered by NewsLook.com
Formerly Conjoined Twins Released From Dallas Hospital

Formerly Conjoined Twins Released From Dallas Hospital

Newsy (Apr. 16, 2014) Conjoined twins Emmett and Owen Ezell were separated by doctors in August. Now, nearly nine months later, they're being released from the hospital. Video provided by Newsy
Powered by NewsLook.com
Ebola Outbreak Now Linked To 121 Deaths

Ebola Outbreak Now Linked To 121 Deaths

Newsy (Apr. 15, 2014) The ebola virus outbreak in West Africa is now linked to 121 deaths. Health officials fear the virus will continue to spread in urban areas. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins