Featured Research

from universities, journals, and other organizations

Rett Syndrome Research Reveals High Fracture Risk

Date:
March 10, 2008
Source:
Telethon Institute for Child Health Research
Summary:
Girls and young women with Rett syndrome are nearly four times more likely to suffer a fracture. The study also found that girls with epilepsy and more severe forms of Rett syndrome were more likely to suffer fractures.

Researchers at Perth's Telethon Institute for Child Health Research have found that girls and young women with Rett syndrome are nearly four times more likely to suffer a fracture.

The head of the Australian Rett Syndrome Study based at the Institute, Dr Helen Leonard, said the results had important implications for the care of girls with the syndrome.

"Many of the girls had fractures of the femur which are particularly disabling given the limited mobility of many of these children," Dr Leonard said.

"This information will be important for doctors and for families in both identifying fractures and endeavouring to find ways to prevent them where possible."

Dr Leonard said the study had found that girls with epilepsy and more severe forms of Rett syndrome were more likely to suffer fractures. "Our next step will be to try to identify the mechanism that is making the girls more susceptible to fractures which will include looking at the effect of the specific gene that's responsible for the syndrome and also the impact of the drug therapies used for epilepsy," Dr Leonard said.

"The high incidence of fracture impacts on the quality of life, care needs and outcomes for this group and their families. We have shown previously that having a child with a fracture impacts in a negative way on the mother's mental health status."

The findings have just been published in the latest edition of the journal Paediatrics.

The Australian Rett Syndrome program receives funding from the National Institutes of Health (USA) and the National Health and Medical Research Council (NHMRC).

About Rett syndrome

Rett syndrome is a relatively rare but serious neurological disorder that usually affects girls. The clinical diagnosis has often been uncertain in early childhood as the symptoms may be confused with those occurring in other disorders such as autism, cerebral palsy and developmental delay. Rett syndrome affects around one in every 8,500 female births. Mutations in the MECP2 gene on the X chromosome have been identified as a cause of Rett syndrome. There is no known cure.


Story Source:

The above story is based on materials provided by Telethon Institute for Child Health Research. Note: Materials may be edited for content and length.


Cite This Page:

Telethon Institute for Child Health Research. "Rett Syndrome Research Reveals High Fracture Risk." ScienceDaily. ScienceDaily, 10 March 2008. <www.sciencedaily.com/releases/2008/03/080307095231.htm>.
Telethon Institute for Child Health Research. (2008, March 10). Rett Syndrome Research Reveals High Fracture Risk. ScienceDaily. Retrieved April 24, 2014 from www.sciencedaily.com/releases/2008/03/080307095231.htm
Telethon Institute for Child Health Research. "Rett Syndrome Research Reveals High Fracture Risk." ScienceDaily. www.sciencedaily.com/releases/2008/03/080307095231.htm (accessed April 24, 2014).

Share This



More Health & Medicine News

Thursday, April 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Deadly Fungus Killing Bats, Spreading in US

Deadly Fungus Killing Bats, Spreading in US

AP (Apr. 24, 2014) A disease that has killed more than six million cave-dwelling bats in the United States is on the move and wildlife biologists are worried. White Nose Syndrome, discovered in New York in 2006, has now spread to 25 states. (April 24) Video provided by AP
Powered by NewsLook.com
Companies Ramp Up Wellness to Lower Health Costs

Companies Ramp Up Wellness to Lower Health Costs

AP (Apr. 24, 2014) That little voice telling you to exercise, get in shape and get healthy is probably coming from your boss. More companies are beefing up wellness programs to try and cut down their health care costs. (April 24) Video provided by AP
Powered by NewsLook.com
Blood From World's Oldest Woman Suggests Life Limit

Blood From World's Oldest Woman Suggests Life Limit

Newsy (Apr. 24, 2014) Scientists say for the extremely elderly, their stem cells might reach a state of exhaustion. This could limit one's life span. Video provided by Newsy
Powered by NewsLook.com
FDA Wants To Ban Sales Of E-Cigarettes To Minors

FDA Wants To Ban Sales Of E-Cigarettes To Minors

Newsy (Apr. 24, 2014) The Food and Drug Administration wants to crack down on the use of e-cigarettes, banning the sale of the product to minors. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins