Featured Research

from universities, journals, and other organizations

Glaucoma Associated With Increased Risk Of Cardiovascular Death In Black Patients, Study Shows

Date:
March 13, 2008
Source:
JAMA and Archives Journals
Summary:
Black patients with diagnosed and treated glaucoma and those with high pressure in their eyes appear to have an increased risk of death from cardiovascular causes, according to a new article.

Black patients with diagnosed and treated glaucoma and those with high pressure in their eyes appear to have an increased risk of death from cardiovascular causes, according to a new report.

"Glaucoma is one of the leading causes of visual impairment worldwide," the authors write as background information in the article. "The most common type, primary open-angle glaucoma, is especially prevalent in populations of African origin, in which it is the foremost cause of blindness." In addition to higher rates of open-angle glaucoma, black populations also tend to have higher rates of death from chronic disease and high pressure within their eyes (ocular hypertension) than white populations.

Suh-Yuh Wu, M.A., of Stony Brook University, Stony Brook, New York, and colleagues studied 4,092 participants age 40 to 84 (average age 58.6) in the Barbados Eye Studies, which assess a predominately black population with similar ancestry to African-Americans. Initial visits occurred between 1987 and 1992. Height, weight and blood pressure were recorded; interviews were conducted; and various eye measurements were taken. These included photographs of the retina and measurements of eye pressure.

At the beginning of the study, 300 participants had glaucoma, including 141 who had been diagnosed and treated. After nine years of follow-up, 764 (19 percent) of the participants had died. After adjusting for other factors, glaucoma was not associated with the risk of death overall. However, the risk of death from cardiovascular causes was 38 percent higher in individuals who had previously been diagnosed with or treated for open-angle glaucoma and 91 percent higher in those who had been treated with one particular agent, the beta-blocker timolol maleate. Cardiovascular deaths were also 28 percent higher in those with ocular hypertension at the beginning of the study.

"One explanation for the excess mortality [death] found in persons with previously diagnosed open-angle glaucoma could be their longer duration of disease compared with those with newly diagnosed disease," the authors write. "Another explanation for an increased mortality risk could be related to the open-angle glaucoma treatment received." Adverse effects or inappropriate use of beta-blockers and other medications used to treat glaucoma may harm the cardiovascular system and increase death risk.

Some evidence suggests that risk factors for ocular hypertension and cardiovascular disease are similar, potentially explaining the increased risk of death associated with ocular hypertension, the authors note. "These findings underscore the importance of close monitoring and controlling of adequate intraocular pressure levels in this and other high-risk populations," they conclude.

Journal reference: Arch Ophthalmol. 2008;126[3]:365-370.

This study was supported by grants from the National Eye Institute, Bethesda, Md.


Story Source:

The above story is based on materials provided by JAMA and Archives Journals. Note: Materials may be edited for content and length.


Cite This Page:

JAMA and Archives Journals. "Glaucoma Associated With Increased Risk Of Cardiovascular Death In Black Patients, Study Shows." ScienceDaily. ScienceDaily, 13 March 2008. <www.sciencedaily.com/releases/2008/03/080310164909.htm>.
JAMA and Archives Journals. (2008, March 13). Glaucoma Associated With Increased Risk Of Cardiovascular Death In Black Patients, Study Shows. ScienceDaily. Retrieved April 20, 2014 from www.sciencedaily.com/releases/2008/03/080310164909.htm
JAMA and Archives Journals. "Glaucoma Associated With Increased Risk Of Cardiovascular Death In Black Patients, Study Shows." ScienceDaily. www.sciencedaily.com/releases/2008/03/080310164909.htm (accessed April 20, 2014).

Share This



More Health & Medicine News

Sunday, April 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Nine-Month-Old Baby Can't Open His Mouth

Nine-Month-Old Baby Can't Open His Mouth

Newsy (Apr. 19, 2014) Nine-month-old Wyatt Scott was born with a rare disorder called congenital trismus, which prevents him from opening his mouth. Video provided by Newsy
Powered by NewsLook.com
'Holy Grail' Of Weight Loss? New Find Could Be It

'Holy Grail' Of Weight Loss? New Find Could Be It

Newsy (Apr. 18, 2014) In a potential breakthrough for future obesity treatments, scientists have used MRI scans to pinpoint brown fat in a living adult for the first time. Video provided by Newsy
Powered by NewsLook.com
Little Progress Made In Fighting Food Poisoning, CDC Says

Little Progress Made In Fighting Food Poisoning, CDC Says

Newsy (Apr. 18, 2014) A new report shows rates of two foodborne infections increased in the U.S. in recent years, while salmonella actually dropped 9 percent. Video provided by Newsy
Powered by NewsLook.com
Scientists Create Stem Cells From Adult Skin Cells

Scientists Create Stem Cells From Adult Skin Cells

Newsy (Apr. 17, 2014) The breakthrough could mean a cure for some serious diseases and even the possibility of human cloning, but it's all still a way off. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins