Featured Research

from universities, journals, and other organizations

Chronic Sleep Disruption Can Cause Heart And Kidney Disease

Date:
March 18, 2008
Source:
University Health Network
Summary:
Chronic sleep disruption can cause heart and kidney disease. The importance of circadian rhythms - the body's "hard-wired" 24-hour sleep-wake cycle, is well understood in the regulation of cardiovascular physiology. Earlier studies have suggested that renewal of cardiovascular tissues predominantly occur during sleep; therefore sleep interruption can directly damage organs.

Chronic sleep disruption can cause heart and kidney disease, researchers at the Peter Munk Cardiac Centre of the Toronto General Hospital have discovered.

“Disrupted circadian rhythms have a devastating effect on the heart, kidney and possibly other organs,” says Dr. Michael Sole, Cardiologist and founding director of the Peter Munk Cardiac Centre and Professor of Medicine and Physiology at the University of Toronto. “This is the first study of its kind to demonstrate that sleep cycle disruption actually causes heart and kidney disease.”

Researchers found when internal biological clocks in hamsters are out of sync with external rhythm regulators (i.e. light/dark), the heart becomes damaged and enlarged (cardiomyopathy), and the kidney tubules sustain significant scarring.

The importance of circadian rhythms - the body’s “hard-wired” 24-hour sleep-wake cycle, is well understood in the regulation of cardiovascular physiology. Earlier studies by Dr. Sole and his colleagues suggested that renewal of cardiovascular tissues predominantly occur during sleep; therefore sleep interruption can directly damage organs.

Trans-meridian flight crews, truck drivers and shift workers often suffer from sleep cycle disruption due to the nature of their jobs. Although the medical focus has largely been on neuropsychological factors such as task performance and memory, these groups are known to have a higher than average prevalence of cardiovascular disease.

“Shift workers and flight-crews might want to consider these findings when scheduling work time,” suggests Dr. Sole, adding that these workers could try to maintain a constant working schedule for one month or more, allowing the body to readjust its clock to external cues. Dr. Sole also notes that some hospitals, particularly in intensive care units, still use multi-bedded rooms, continually disrupting sleep-wake cycles in the critically ill.

The study entitled, “Circadian rhythm disorganization produces profound cardiovascular and renal disease in hamsters,” was published in the April edition of the American Journal of Physiology- Regulatory, Integrative and Comparative Physiology. The Heart and Stroke Foundation and the A. Ephraim and Shirley Diamond Cardiomyopathy Research Fund funded this study.


Story Source:

The above story is based on materials provided by University Health Network. Note: Materials may be edited for content and length.


Cite This Page:

University Health Network. "Chronic Sleep Disruption Can Cause Heart And Kidney Disease." ScienceDaily. ScienceDaily, 18 March 2008. <www.sciencedaily.com/releases/2008/03/080313211420.htm>.
University Health Network. (2008, March 18). Chronic Sleep Disruption Can Cause Heart And Kidney Disease. ScienceDaily. Retrieved September 20, 2014 from www.sciencedaily.com/releases/2008/03/080313211420.htm
University Health Network. "Chronic Sleep Disruption Can Cause Heart And Kidney Disease." ScienceDaily. www.sciencedaily.com/releases/2008/03/080313211420.htm (accessed September 20, 2014).

Share This



More Health & Medicine News

Saturday, September 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Changes Found In Brain After One Dose Of Antidepressants

Changes Found In Brain After One Dose Of Antidepressants

Newsy (Sep. 19, 2014) — A study suggest antidepressants can kick in much sooner than previously thought. Video provided by Newsy
Powered by NewsLook.com
Could Grief Affect The Immune Systems Of Senior Citizens?

Could Grief Affect The Immune Systems Of Senior Citizens?

Newsy (Sep. 19, 2014) — The study found elderly people are much more likely to become susceptible to infection than younger adults going though a similar situation. Video provided by Newsy
Powered by NewsLook.com
Jury Delivers Verdict in Salmonella Trial

Jury Delivers Verdict in Salmonella Trial

AP (Sep. 19, 2014) — A federal jury has convicted three people in connection with an outbreak of salmonella poisoning five years ago that sickened hundreds of people and was linked to a number of deaths. (Sept. 19) Video provided by AP
Powered by NewsLook.com
How The 'Angelina Jolie Effect' Increased Cancer Screenings

How The 'Angelina Jolie Effect' Increased Cancer Screenings

Newsy (Sep. 19, 2014) — Angelina's Jolie's decision to undergo a preventative mastectomy in 2013 inspired many women to seek early screenings for the disease. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins