Featured Research

from universities, journals, and other organizations

Younger Age, Involvement On Neck Or Arms Associated With Abnormal Scarring After Burn Injury

Date:
March 17, 2008
Source:
JAMA and Archives Journals
Summary:
Sex, age, burn site, number of surgical procedures and the type of skin graft are associated with abnormal scarring following burns, according to a new article. The survival rate of patients with burns has dramatically increased over the past few decades, but healing burns almost always form scars.

Sex, age, burn site, number of surgical procedures and the type of skin graft are associated with abnormal scarring following burns, according to a new article.

The survival rate of patients with burns has dramatically increased over the past few decades, but healing burns almost always form scars, according to background information in the article. "Burn scars have a dramatic influence on a patient's quality of life," the authors write. "They have been associated with anxiety, social avoidance, depression, a disruption in activities of daily living, the onset of sleep disturbances and all of the consequent difficulties in returning to normal life after physical rehabilitation."

Normal scars are characterized by minor alterations in skin properties, whereas disturbances in the wound healing process produce abnormal or pathologic scars. Ezio Nicola Gangemi, M.D., and colleagues at the University of Turin, Italy, analyzed the records of 703 patients treated at an outpatient burn clinic between 1994 and 2006. In addition to the sex, age, total burn surface, cause of the burn and wound healing time, they noted the prevalence and evolution of several types of pathologic scars: hypertrophic (enlarged) scars; contracted scars, which shorten the length of the tissue; and scars with both characteristics.

Of the 703 patients, 540 (77 percent) had pathologic scars, including 310 (44 percent) with hypertrophic scars, 34 (5 percent) with contractures and 196 (28 percent) with hypertrophic-contracted scars. Patients who were female, young, burned on the neck or arms, had multiple surgical procedures or received meshed skin grafts (sections of skin that have been mechanically cut and expanded, as opposed to sheet or solid grafts) all had a higher risk of pathologic scarring.

Questions remain regarding the clinical course of post-burn scarring, the authors note. "Our data seem to support the role of the immune system for a number of reasons," they write. Females have a higher risk for both pathologic burn scarring and most immune-related diseases, including rheumatoid arthritis and lupus. In addition, younger patients with more active immune systems are also more likely to develop abnormal scars.

The results could improve physicians' approach to post-burn scarring, the authors note. "Risk information may be easily integrated into routine clinical practice for early risk stratification, thus facilitating optimal medical prevention and helping physicians adopt follow-up timing and more aggressive or experimental therapies for subjects likely to be at high risk," they write.

Journal reference: Arch Facial Plast Surg. 2008;10[2]:93-102.


Story Source:

The above story is based on materials provided by JAMA and Archives Journals. Note: Materials may be edited for content and length.


Cite This Page:

JAMA and Archives Journals. "Younger Age, Involvement On Neck Or Arms Associated With Abnormal Scarring After Burn Injury." ScienceDaily. ScienceDaily, 17 March 2008. <www.sciencedaily.com/releases/2008/03/080317164409.htm>.
JAMA and Archives Journals. (2008, March 17). Younger Age, Involvement On Neck Or Arms Associated With Abnormal Scarring After Burn Injury. ScienceDaily. Retrieved September 17, 2014 from www.sciencedaily.com/releases/2008/03/080317164409.htm
JAMA and Archives Journals. "Younger Age, Involvement On Neck Or Arms Associated With Abnormal Scarring After Burn Injury." ScienceDaily. www.sciencedaily.com/releases/2008/03/080317164409.htm (accessed September 17, 2014).

Share This



More Health & Medicine News

Wednesday, September 17, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

President To Send 3,000 Military Personnel To Fight Ebola

President To Send 3,000 Military Personnel To Fight Ebola

Newsy (Sep. 16, 2014) President Obama is expected to send 3,000 troops to West Africa as part of the effort to contain Ebola's spread. Video provided by Newsy
Powered by NewsLook.com
Obama Orders Military Response to Ebola

Obama Orders Military Response to Ebola

AP (Sep. 16, 2014) Calling the Ebola outbreak in West Africa a potential threat to global security, President Barack Obama is ordering 3,000 U.S. military personnel to the stricken region amid worries that the outbreak is spiraling out of control. (Sept. 16) Video provided by AP
Powered by NewsLook.com
UN: 20,000 Could Be Infected With Ebola by Year End

UN: 20,000 Could Be Infected With Ebola by Year End

AFP (Sep. 16, 2014) Nearly $1.0 billion dollars is needed to fight the Ebola outbreak raging in west Africa, the United Nations say, warning that 20,000 could be infected by year end. Duration: 00:40 Video provided by AFP
Powered by NewsLook.com
Obama: Ebola Outbreak Threat to Global Security

Obama: Ebola Outbreak Threat to Global Security

AP (Sep. 16, 2014) President Obama is ordering U.S. military personnel to West Africa to deal with the Ebola outbreak, which is he calls a potential threat to global security. (Sept. 16) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

    Technology News



    Save/Print:
    Share:

    Free Subscriptions


    Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

    Get Social & Mobile


    Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

    Have Feedback?


    Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
    Mobile: iPhone Android Web
    Follow: Facebook Twitter Google+
    Subscribe: RSS Feeds Email Newsletters
    Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins