Featured Research

from universities, journals, and other organizations

Uterine Stem Cells Create New Neurons That Can Curb Parkinson's Disease

Date:
April 1, 2008
Source:
Yale University
Summary:
The injection of uterine stem cells trigger growth of new brain cells in mice with Parkinson's disease, Yale School of Medicine researchers report.

The injection of uterine stem cells trigger growth of new brain cells in mice with Parkinson's disease, Yale School of Medicine researchers report.

Related Articles


"Previously, we were able to coax these multipotent stem cells to differentiate into cartilage cells," said lead author Hugh S. Taylor, M.D., professor in the Department of Obstetrics, Gynecology & Reproductive Sciences at Yale School of Medicine and section chief of Reproductive Endocrinology and Infertility at Yale School of Medicine. "Now we have found that we can turn uterine stem cells into neurons that can boost dopamine levels and partially correct the problem of Parkinson's disease."

Parkinson's disease is a degenerative disorder of the central nervous system that often impairs the sufferer's motor skills and speech. The primary symptoms are the results of decreased stimulation of the motor cortex by the basal ganglia, which is normally caused by the insufficient formation and action of dopamine.

The stem cells in this study were derived from human endometrial stromal cells that were cultured under conditions that induce the creation of neurons. These cells then developed axon-like projections and cell bodies with a pyramid shape typical of neurons.

"The dopamine levels in the mice increased once we transferred the stem cells into their brains," Taylor said. "The implications of our findings are that women have a ready supply of stem cells that are easily obtained, are differentiable into other cell types, and have great potential use for other purposes."

This research was presented in an abstract presented at the 2008 Society for Gynecologic Investigation (SGI) Annual Scientific Meeting held March 26-29 in San Diego, California.

Other authors include Erin Wolff, M.D., who will present the abstract at SGI, Zane B. Andrews, Xiao-Bing Gao and Katherine V. Yao. This abstract is an SGI Trainee Plenary Session Selection and winner of the SGI President's Presenter Award.


Story Source:

The above story is based on materials provided by Yale University. Note: Materials may be edited for content and length.


Cite This Page:

Yale University. "Uterine Stem Cells Create New Neurons That Can Curb Parkinson's Disease." ScienceDaily. ScienceDaily, 1 April 2008. <www.sciencedaily.com/releases/2008/03/080331093533.htm>.
Yale University. (2008, April 1). Uterine Stem Cells Create New Neurons That Can Curb Parkinson's Disease. ScienceDaily. Retrieved November 20, 2014 from www.sciencedaily.com/releases/2008/03/080331093533.htm
Yale University. "Uterine Stem Cells Create New Neurons That Can Curb Parkinson's Disease." ScienceDaily. www.sciencedaily.com/releases/2008/03/080331093533.htm (accessed November 20, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, November 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

UN Says It Will Scale Up Its Ebola Response

UN Says It Will Scale Up Its Ebola Response

AFP (Nov. 20, 2014) UN Resident Coordinator David McLachlan-Karr and WHO representative in the country Daniel Kertesz updated the media on the UN Ebola response on Wednesday. Duration: 00:51 Video provided by AFP
Powered by NewsLook.com
Takata Offers "sincerest Condolences" To Victims of Malfunctioning Airbag

Takata Offers "sincerest Condolences" To Victims of Malfunctioning Airbag

Reuters - US Online Video (Nov. 20, 2014) U.S. Congress hears from a victim and company officials as it holds a hearing on the safety of Takata airbags after reports of injuries. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com
Obesity Costs Almost As Much As War And Terrorism

Obesity Costs Almost As Much As War And Terrorism

Newsy (Nov. 20, 2014) The newest estimate of the cost of obesity is pretty jarring — $2 trillion. But how did researchers get to that number? Video provided by Newsy
Powered by NewsLook.com
Ebola Crisis Affecting US Adoptions

Ebola Crisis Affecting US Adoptions

AP (Nov. 20, 2014) The Sanborn family had hoped they'd be able to bring home their 5-year-old adopted son from Liberia by now. But Ebola has forced them to wait. The boy is just one of thousands of orphans in West Africa who've been impacted by the deadly virus. (Nov. 20) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins