Featured Research

from universities, journals, and other organizations

Salivary Diagnostics, The 'Magic Mirror' To Your Health ... At Your Personal Computer

Date:
April 5, 2008
Source:
International & American Association for Dental Research
Summary:
Accuracy, convenience and noninvasiveness are the most critical characteristics for any diagnostic tool. A new concept, Salivaomics Knowledge Base, an in silico saliva diagnostic atlas, is being launched.

Accuracy, convenience, and non-invasiveness are the most critical characteristics for any diagnostic tool. A new concept, Salivaomics Knowledge Base (SKB), an in silico (i.e., performed on computer or via computer simulation) saliva diagnostic atlas, is launching during the 37th Annual Meeting of the American Association for Dental Research in Dallas, Texas.

With people increasingly adopting a 'digital life', the SKB will serve as a catalyst for future development and expansion of salivary diagnostics. For over three years, saliva has shown genuine promise as a diagnostic tool for oral cancer detection. As a result, the scientific community and general public have developed a keen interest in its value.

Central to the SKB is the recent creation of two diagnostic alphabets in saliva, the proteome and the transcriptome. In the SKB, the salivary proteome and transcriptome are mapped to 23 human chromosomes, totaling1166 distinct proteins and 851 unique mRNA transcripts in saliva. The available information presently includes profiles from healthy males and females, as well as oral cancer patients.

These profiles can be used to determine distinct differences between groups of interest. For example, if one wants to know the differences in the salivary protein or transcriptome profiles of males and females, the user-friendly interface can be utilized to retrieve information from the database. First, an overview of the biomarker distribution on the 23 human chromosomes can be determined. Then, one can zoom in on specific gene segments to extract more detailed information, all done on one's personal computer.

This is the first step of this SKB initiative. The database is expanding and will soon include information for pancreatic cancer, breast cancer, lung cancer, ovarian cancer, diabetes,and Alzheimer's disease. The short-term goal of the SKB is to share information with scientists globally in an effort to reduce redundancy and enhance the appeal of salivary diagnostics.

This is a summary of abstract #1179, "Salivaomics Knowledge Base (SKB)", by W. Yan et al., of UCLA, USA, presented April 5, 2008 during the 37th Annual Meeting of the American Association for Dental Research.


Story Source:

The above story is based on materials provided by International & American Association for Dental Research. Note: Materials may be edited for content and length.


Cite This Page:

International & American Association for Dental Research. "Salivary Diagnostics, The 'Magic Mirror' To Your Health ... At Your Personal Computer." ScienceDaily. ScienceDaily, 5 April 2008. <www.sciencedaily.com/releases/2008/04/080405095750.htm>.
International & American Association for Dental Research. (2008, April 5). Salivary Diagnostics, The 'Magic Mirror' To Your Health ... At Your Personal Computer. ScienceDaily. Retrieved August 29, 2014 from www.sciencedaily.com/releases/2008/04/080405095750.htm
International & American Association for Dental Research. "Salivary Diagnostics, The 'Magic Mirror' To Your Health ... At Your Personal Computer." ScienceDaily. www.sciencedaily.com/releases/2008/04/080405095750.htm (accessed August 29, 2014).

Share This




More Health & Medicine News

Friday, August 29, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

3 Things To Know About The Ebola Outbreak's Progression

3 Things To Know About The Ebola Outbreak's Progression

Newsy (Aug. 29, 2014) Here are three things you need to know about the deadly Ebola outbreak's progression this week. Video provided by Newsy
Powered by NewsLook.com
Killer Amoeba Found in Louisiana Water System

Killer Amoeba Found in Louisiana Water System

AP (Aug. 28, 2014) State health officials say testing has confirmed the presence of a killer amoeba in a water system serving three St. John the Baptist Parish towns. (Aug. 28) Video provided by AP
Powered by NewsLook.com
Who Could Be Burnt by WHO's E-Cigs Move?

Who Could Be Burnt by WHO's E-Cigs Move?

Reuters - Business Video Online (Aug. 28, 2014) The World Health Organisation has called for the regulation of electronic cigarettes as both tobacco and medical products. Ciara Lee looks at the impact of the move on the tobacco industry. Video provided by Reuters
Powered by NewsLook.com
CDC Director On Ebola Outbreak: 'It's Worse Than I Feared'

CDC Director On Ebola Outbreak: 'It's Worse Than I Feared'

Newsy (Aug. 28, 2014) CDC director Tom Frieden says the Ebola outbreak is even worse than he feared. But he also said there's still hope to contain it. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins