Featured Research

from universities, journals, and other organizations

Transmitting Prion Diseases In Milk

Date:
April 8, 2008
Source:
BMC Veterinary Research
Summary:
Scrapie can be transmitted to lambs through milk, according to new research. The study provides important information on the transmission of this prion-associated disease and the control of scrapie in affected flocks.

Scrapie can be transmitted to lambs through milk, according to new research. The study provides important information on the transmission of this prion-associated disease and the control of scrapie in affected flocks. Scrapie is a fatal neurodegenerative disease of sheep and goats. Clinical signs include itchiness, head tremor, wool loss and skin lesions as well as changes in behaviour and gait.

Timm Konold and colleagues from the Veterinary Laboratories Agency in Weybridge, UK, investigated the transmission of scrapie by feeding milk from scrapie-affected ewes to lambs that are genetically susceptible to contracting scrapie. The researchers were looking for the presence of the prion protein, PrPd, which is associated with the disease.

Eighteen lambs were fed milk from scrapie-affected ewes. Three of these lambs were culled and two were found to have PrPd in intestinal tissues. The prion protein was also detected in lymphoid tissue of the gut of the surviving lambs and in some control lambs mixed with the scrapie milk recipients after weaning.

This suggested that scrapie milk recipients were able to shed the infectious agent and infect other lambs. There was no sign of PrPd in tissue samples from a control group of 10 lambs(one culled and the rest alive), which were housed in the same building but fed milk from healthy ewes. The research will continue, to see whether the lambs with PrPd develop the disease as they get older.

This work raises the possibility that other prion diseases could be transmitted in sheep via milk although it should have no direct implications for human health. Scrapie has been found in sheep and has not been shown to be transmissible to humans. BSE has not been found naturally in sheep and occurrence in sheep in the UK is considered to be unlikely. This research adds to our understanding of the transmission of prion diseases in sheep and would help to inform measures needed to protect human health if BSE were ever to be found in sheep.

Journal reference: Evidence of scrapie transmission via milk. Timm Konold, S. Jo Moore, Susan J. Bellworthy, and Hugh A. Simmons. BMC Veterinary Research (in press)


Story Source:

The above story is based on materials provided by BMC Veterinary Research. Note: Materials may be edited for content and length.


Cite This Page:

BMC Veterinary Research. "Transmitting Prion Diseases In Milk." ScienceDaily. ScienceDaily, 8 April 2008. <www.sciencedaily.com/releases/2008/04/080407190603.htm>.
BMC Veterinary Research. (2008, April 8). Transmitting Prion Diseases In Milk. ScienceDaily. Retrieved July 24, 2014 from www.sciencedaily.com/releases/2008/04/080407190603.htm
BMC Veterinary Research. "Transmitting Prion Diseases In Milk." ScienceDaily. www.sciencedaily.com/releases/2008/04/080407190603.htm (accessed July 24, 2014).

Share This




More Plants & Animals News

Thursday, July 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Dogs Appear To Become Jealous Of Owners' Attention

Dogs Appear To Become Jealous Of Owners' Attention

Newsy (July 23, 2014) A U.C. San Diego researcher says jealousy isn't just a human trait, and dogs aren't the best at sharing the attention of humans with other dogs. Video provided by Newsy
Powered by NewsLook.com
Professor Creates Site Revealing Where People's Cats Live

Professor Creates Site Revealing Where People's Cats Live

Newsy (July 23, 2014) ​It's called I Know Where Your Cat Lives, and you can keep hitting the "Random Cat" button to find more real cats all over the world. Video provided by Newsy
Powered by NewsLook.com
Stone Fruit Listeria Scare Causes Sweeping Recall

Stone Fruit Listeria Scare Causes Sweeping Recall

Newsy (July 22, 2014) The Wawona Packing Company has issued a voluntary recall on the stone fruit it distributes due to a possible Listeria outbreak. Video provided by Newsy
Powered by NewsLook.com
Michigan Plant's Goal: Flower and Die

Michigan Plant's Goal: Flower and Die

AP (July 22, 2014) An 80-year-old agave plant, which is blooming for the first and only time at a University of Michigan conservatory, will die when it's done (July 22) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins