Featured Research

from universities, journals, and other organizations

Sunburn Alert: UVB Does More Damage To DNA Than UVA

Date:
July 1, 2008
Source:
Federation of American Societies for Experimental Biology
Summary:
As bombs burst in air this July 4, chances are that sunburn will be the red glare that most folks see -- and feel. But unfortunately, even when there is no burn, the effects of the sun's ultraviolet rays can have deadly consequences. Thanks to new research scientists now know why UVB light is more likely to cause skin cancer than UVA light.

As bombs burst in air this July 4, chances are that sunburn will be the red glare that most folks see -- and feel. But unfortunately, even when there is no burn, the effects of the sun's ultraviolet (UV) rays can have deadly consequences. Scientists now know why one type of UV light (UVB) is more likely to cause skin cancer than the other (UVA).

Related Articles


This information should be useful to public health officials and government regulatory agencies in identifying specific criteria for exactly how effective consumer products, like sunscreen, are in preventing skin damage leading to skin cancer. It should also allow scientists to pursue new lines of research and treatment into repairing the damage caused by the sun's rays.

This research was published in the July 2008 issue of The FASEB Journal. "Our study is novel in that it fills the gaps in knowledge of mechanisms involved in sunlight-associated skin cancers, which cover various aspects of DNA damage and repair and genetic alterations," said Ahmad Besaratinia, PhD, Assistant Research Scientist at City of Hope National Medical Center and first author on the report.

According to researchers from City of Hope National Medical Center in Duarte, California, UVB light is more harmful to our skin because our bodies are less able to repair the DNA damage it causes than the damage caused by UVA light. To reach their conclusions, scientists exposed three sets of cells to UVA light, UVB light and simulated sunlight. Then they compared these cells to an unexposed control group to analyze how well these cells were able to repair the damage.

In addition, they analyzed published data on the genetics involved in human skin cancers. The researchers found that cells were more easily able to repair the damage caused by the UVA light, which explains why UVA light has been perceived as "safer" than UVB light. Despite this perception, scientists and public health experts caution that UVA light can and does cause serious damage that can and does lead to skin cancer.

"We know that sunlight causes skin cancer and that breakdown of the ozone layer exposes us to ever more ultraviolet radiation. This work tells us that both forms of UVA and UVB in sunlight cause damage to DNA. It forms a missing link in the chain of events from sun exposure to tumor formation," said Gerald Weissmann, MD, Editor-in-Chief of The FASEB Journal. "This research article gives us information that could lead to better sunscreens or effective 'after sun' products. It promises new ways to prevent - and perhaps to treat - the epidemic of skin cancer brought on by modern life."

According to the U.S. Centers for Disease Control and Prevention, skin cancer is the most common form of cancer in the United States. Of the top three forms of skin cancer, melanoma is the most dangerous with about 65 percent to 90 percent of melanomas caused by exposure to ultraviolet rays. The other two most common, but less dangerous, types of skin cancer are basal cell and squamous cell carcinomas.


Story Source:

The above story is based on materials provided by Federation of American Societies for Experimental Biology. Note: Materials may be edited for content and length.


Cite This Page:

Federation of American Societies for Experimental Biology. "Sunburn Alert: UVB Does More Damage To DNA Than UVA." ScienceDaily. ScienceDaily, 1 July 2008. <www.sciencedaily.com/releases/2008/07/080701092141.htm>.
Federation of American Societies for Experimental Biology. (2008, July 1). Sunburn Alert: UVB Does More Damage To DNA Than UVA. ScienceDaily. Retrieved December 21, 2014 from www.sciencedaily.com/releases/2008/07/080701092141.htm
Federation of American Societies for Experimental Biology. "Sunburn Alert: UVB Does More Damage To DNA Than UVA." ScienceDaily. www.sciencedaily.com/releases/2008/07/080701092141.htm (accessed December 21, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, December 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Touch-Free Smart Phone Empowers Mobility-Impaired

Touch-Free Smart Phone Empowers Mobility-Impaired

Reuters - Innovations Video Online (Dec. 21, 2014) A touch-free phone developed in Israel enables the mobility-impaired to operate smart phones with just a movement of the head. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com
Earthworms Provide Cancer-Fighting Bacteria

Earthworms Provide Cancer-Fighting Bacteria

Reuters - Innovations Video Online (Dec. 21, 2014) Polish scientists isolate bacteria from earthworm intestines which they say may be used in antibiotics and cancer treatments. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com
Existing Chemical Compounds Could Revive Failing Antibiotics, Says Danish Scientist

Existing Chemical Compounds Could Revive Failing Antibiotics, Says Danish Scientist

Reuters - Innovations Video Online (Dec. 21, 2014) A team of scientists led by Danish chemist Jorn Christensen says they have isolated two chemical compounds within an existing antipsychotic medication that could be used to help a range of failing antibiotics work against killer bacterial infections, such as Tuberculosis. Jim Drury went to meet him. Video provided by Reuters
Powered by NewsLook.com
Hugging It Out Could Help You Ward Off A Cold

Hugging It Out Could Help You Ward Off A Cold

Newsy (Dec. 21, 2014) Carnegie Mellon researchers found frequent hugs can help people avoid stress-related illnesses. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins