Featured Research

from universities, journals, and other organizations

'Healthy' Sterols May Pose Health Risk

Date:
July 16, 2008
Source:
American Society for Biochemistry and Molecular Biology
Summary:
Plant sterols have been touted as an effective way to lower cholesterol and reduce the risk of heart disease. However, a research study has uncovered that these compounds do have their own risks, as they can accumulate in heart valves and lead to stenosis.

Plant sterols have been touted as an effective way to lower cholesterol and reduce the risk of heart disease. However, a research study in the July JLR has uncovered that these compounds do have their own risks, as they can accumulate in heart valves and lead to stenosis.

Related Articles


Aortic valve stenosis (AS) results from cholesterol accumulation in the valve between the left ventricle and aorta; this impedes the flow of blood and puts extra pressure on the heart. About 2% of individuals over 65 (and over 5% of those over 85) have AS, and as the population ages, it is becoming an increasing problem.

Plant sterols can block the absorption of dietary cholesterol into the body, and as such high vegetable diets and/or plant sterol supplements are often used to alleviate high cholesterol. However, although plant sterols themselves are poorly absorbed, they can enter the body, so Satu Helske and colleagues examined whether plant sterols can also accumulate in aortic valves.

They collected blood samples from 82 patients with severe AS and aortic valves from 21 individuals undergoing valve surgery, along with respective controls. They observed that non-cholesterol sterols, including plant sterols, can accumulate in aortic valves, and at levels that directly related to their blood concentration.

These findings suggest that beneficial plant sterols may end up becoming a risk factor for AS, although the researchers will need to conduct more studies, such as whether dietary sterols and sterol supplements produce different effects.


Story Source:

The above story is based on materials provided by American Society for Biochemistry and Molecular Biology. Note: Materials may be edited for content and length.


Journal Reference:

  1. Satu Helske, Tatu Miettinen, Helena Gylling, Mikko Mäyränpää, Jyri Lommi, Heikki Turto, Kalervo Werkkala, Markku Kupari and Petri T. Kovanen. Accumulation of cholesterol precursors and plant sterols in human stenoticaortic valves. Journal of Lipid Research, (in press) [link]

Cite This Page:

American Society for Biochemistry and Molecular Biology. "'Healthy' Sterols May Pose Health Risk." ScienceDaily. ScienceDaily, 16 July 2008. <www.sciencedaily.com/releases/2008/07/080714165856.htm>.
American Society for Biochemistry and Molecular Biology. (2008, July 16). 'Healthy' Sterols May Pose Health Risk. ScienceDaily. Retrieved January 27, 2015 from www.sciencedaily.com/releases/2008/07/080714165856.htm
American Society for Biochemistry and Molecular Biology. "'Healthy' Sterols May Pose Health Risk." ScienceDaily. www.sciencedaily.com/releases/2008/07/080714165856.htm (accessed January 27, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Tuesday, January 27, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Mistakes Should Serve a Lesson Says WHO

Ebola Mistakes Should Serve a Lesson Says WHO

AFP (Jan. 25, 2015) — The World Health Organization&apos;s chief on Sunday admitted the UN agency had been caught napping on Ebola, saying it should serve a lesson to avoid similar mistakes in future. Duration: 00:55 Video provided by AFP
Powered by NewsLook.com
Disneyland Measles Outbreak Spreads To 5 States

Disneyland Measles Outbreak Spreads To 5 States

Newsy (Jan. 24, 2015) — Much of the Disneyland measles outbreak is being blamed on the anti-vaccination movement. The CDC encourages just about everyone get immunized. Video provided by Newsy
Powered by NewsLook.com
Growing Measles Outbreak Worries Calif. Parents

Growing Measles Outbreak Worries Calif. Parents

AP (Jan. 23, 2015) — Public health officials are rushing to contain a measles outbreak that has sickened 70 people across 6 states and Mexico. The AP&apos;s Raquel Maria Dillon has more. (Jan. 23) Video provided by AP
Powered by NewsLook.com
Smart Wristband to Shock Away Bad Habits

Smart Wristband to Shock Away Bad Habits

Reuters - Innovations Video Online (Jan. 23, 2015) — A Boston start-up is developing a wristband they say will help users break bad habits by jolting them with an electric shock. Ben Gruber reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

    Health News

    Environment News

    Technology News



    Save/Print:
    Share:  

    Free Subscriptions


    Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

    Get Social & Mobile


    Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

    Have Feedback?


    Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
    Mobile iPhone Android Web
    Follow Facebook Twitter Google+
    Subscribe RSS Feeds Email Newsletters
    Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins