Featured Research

from universities, journals, and other organizations

No Need For Gene Screens In Breast Cancer Families, Study Shows

Date:
July 25, 2008
Source:
BMC Cancer
Summary:
New research should provide relief to women who are worried after a relative's breast cancer diagnosis. A new study shows that a family history of breast cancer does not give a useful indication of the likelihood that a woman will develop it herself at an early age.

Research reported today should provide relief to women who are worried after a relative's breast cancer diagnosis. The study shows that a family history of breast cancer does not give a useful indication of the likelihood that a woman will develop it herself at an early age.

Related Articles


An increased risk of breast cancer for relatives of breast cancer patients has been demonstrated in many studies. As physicians and the general population have become more aware of this increased risk, the demand for referring healthy women with a family history of breast cancer for intensive screening or genetic testing has risen. Geertruida H. de Bock led a team from Leiden University Medical Centre in the Netherlands who investigated whether the increased risk was significant enough to accurately predict breast cancer.

According to de Bock, "Due to the low prevalence of early breast cancer in the population, the predictive value of a family history of breast cancer was 13% before the age of 70, 11% before the age of 50, and 1% before the age of 30." These numbers are much lower than most women would probably expect. As the authors explain, "Applying family history related criteria results in the screening of many women who will not develop breast cancer at an early age."

Given the psychological harm that screening visits can cause, more stringent criteria should be applied to early screening. The researchers recommend that these results be used to "reassure a large number of women regarding their personal breast cancer risk."


Story Source:

The above story is based on materials provided by BMC Cancer. Note: Materials may be edited for content and length.


Journal Reference:

  1. Geertruida H De Bock, Catharina E Jacobi, Caroline Seynaeve, Elly M.M. Krol-Warmerdam, Jannet Blom, Christi J. Van Asperen, Cees J. Cornelisse, Jan G.M. Klijn, Peter Devilee, Rob A.E.M. Tollenaar, Cecile T.M Brekelmans and Johannes C. Van Houwelingen. A family history of breast cancer will not predict female early onset breast cancer in a population-based setting. BMC Cancer (in press), (in press)

Cite This Page:

BMC Cancer. "No Need For Gene Screens In Breast Cancer Families, Study Shows." ScienceDaily. ScienceDaily, 25 July 2008. <www.sciencedaily.com/releases/2008/07/080722192348.htm>.
BMC Cancer. (2008, July 25). No Need For Gene Screens In Breast Cancer Families, Study Shows. ScienceDaily. Retrieved December 17, 2014 from www.sciencedaily.com/releases/2008/07/080722192348.htm
BMC Cancer. "No Need For Gene Screens In Breast Cancer Families, Study Shows." ScienceDaily. www.sciencedaily.com/releases/2008/07/080722192348.htm (accessed December 17, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Wednesday, December 17, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

AFP (Dec. 17, 2014) Border closures, quarantines and crop losses in West African nations battling the Ebola virus could lead to as many as one million people going hungry, UN food agencies said on Wednesday. Duration: 00:52 Video provided by AFP
Powered by NewsLook.com
When You Lose Weight, This Is Where The Fat Goes

When You Lose Weight, This Is Where The Fat Goes

Newsy (Dec. 17, 2014) Can fat disappear into thin air? New research finds that during weight loss, over 80 percent of a person's fat molecules escape through the lungs. Video provided by Newsy
Powered by NewsLook.com
Why Your Boss Should Let You Sleep In

Why Your Boss Should Let You Sleep In

Newsy (Dec. 17, 2014) According to research out of the University of Pennsylvania, waking up for work is the biggest factor that causes Americans to lose sleep. Video provided by Newsy
Powered by NewsLook.com
Flu Outbreak Closing Schools in Ohio

Flu Outbreak Closing Schools in Ohio

AP (Dec. 17, 2014) A wave of flu illnesses has forced some Ohio schools to shut down over the past week. State officials confirmed one pediatric flu-related death, a 15-year-old girl in southern Ohio. (Dec. 17) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins