Featured Research

from universities, journals, and other organizations

Right Place + Right Time Can Trigger Drinking

Date:
July 31, 2008
Source:
Elsevier
Summary:
Strong cravings for alcohol can be sparked by the mere sight, smell and taste of a person's favorite drink. Responses to such cues that are associated with the positive effects of drinking are a lead cause of relapse in abstinent alcoholics. Using a behavioral animal model, researchers of a new study have found that the physical surroundings where alcohol cues are experienced can greatly influence the ability of those cues to trigger relapse.

Strong cravings for alcohol can be sparked by the mere sight, smell and taste of a person’s favorite drink. Responses to such cues that are associated with the positive effects of drinking are a lead cause of relapse in abstinent alcoholics.

Using a behavioral animal model, researchers of a new study, scheduled for publication in the August 1st issue of Biological Psychiatry, have found that the physical surroundings where alcohol cues are experienced can greatly influence the ability of those cues to trigger relapse.

Specifically, Chaudhri and colleagues taught rats to learn that a brief tone signaled when a small amount of alcohol would be available in a fluid receptacle for them to drink. This learning occurred in a distinctive environment consisting of a particular appearance, smell, and lighting. They were then put into a second, unique context with a different appearance, smell, and lighting, and were repeatedly exposed to the tone but never given alcohol.

After several sessions in this new context, the rats gradually learned that the tone no longer predicted alcohol and consequently stopped checking the fluid receptacle. However, upon re-exposure to the original context where alcohol was available, presentation of the tone once again caused the rats to immediately check for it. “This finding demonstrates the power of environments to trigger relapse to alcohol-seeking in response to alcohol-predictive cues,“ said lead author Nadia Chaudhri, Ph. D., with the Ernest Gallo Clinic and Research Center at UCSF. “This effect is highly detrimental to humans who are trying to abstain from drinking.”

Additionally, the authors also found that the capacity of an alcohol-associated context to trigger relapse to alcohol cues can be greatly diminished by presenting the cues repeatedly in multiple distinct contexts without alcohol. If used in the clinic, this technique of extinguishing responses to alcohol cues in multiple contexts could greatly increase the efficacy of current behavioral treatments for alcoholism. John H. Krystal, M.D., Editor of Biological Psychiatry and affiliated with both Yale University School of Medicine and the VA Connecticut Healthcare System, further elaborates on this idea, commenting that “it is possible that exposure-based therapies could occur in a broader range of contexts so as to enhance their effectiveness. These contexts could be real, i.e., visiting bars or liquor stores, could be created using virtual reality techniques, or could simply be recreated by patients as they imagined visiting places that triggered their urges to drink.” Additional research will clearly need to be undertaken to determine the effectiveness of such a technique, but these findings indicate that it may be a promising addition to addiction therapies.


Story Source:

The above story is based on materials provided by Elsevier. Note: Materials may be edited for content and length.


Cite This Page:

Elsevier. "Right Place + Right Time Can Trigger Drinking." ScienceDaily. ScienceDaily, 31 July 2008. <www.sciencedaily.com/releases/2008/07/080729075111.htm>.
Elsevier. (2008, July 31). Right Place + Right Time Can Trigger Drinking. ScienceDaily. Retrieved October 21, 2014 from www.sciencedaily.com/releases/2008/07/080729075111.htm
Elsevier. "Right Place + Right Time Can Trigger Drinking." ScienceDaily. www.sciencedaily.com/releases/2008/07/080729075111.htm (accessed October 21, 2014).

Share This



More Mind & Brain News

Tuesday, October 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Your Birth Season Might Determine Your Temperament

Your Birth Season Might Determine Your Temperament

Newsy (Oct. 20, 2014) A new study says the season you're born in can determine your temperament — and one season has a surprising outcome. Video provided by Newsy
Powered by NewsLook.com
Court Ruling Means Kids' Online Activity Could Be On Parents

Court Ruling Means Kids' Online Activity Could Be On Parents

Newsy (Oct. 17, 2014) In a ruling attorneys for both sides agreed was a first of its kind, a Georgia appeals court said parents can be held liable for what kids put online. Video provided by Newsy
Powered by NewsLook.com
The Best Foods To Boost Your Mood

The Best Foods To Boost Your Mood

Buzz60 (Oct. 17, 2014) Feeling down? Reach for the refrigerator, not the medicine cabinet! TC Newman (@PurpleTCNewman) shares some of the best foods to boost your mood. Video provided by Buzz60
Powered by NewsLook.com
You Can Get Addicted To Google Glass, Apparently

You Can Get Addicted To Google Glass, Apparently

Newsy (Oct. 15, 2014) Researchers claim they’ve diagnosed the first example of the disorder in a 31-year-old U.S. Navy serviceman. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins