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Levels Of C-reactive Protein In The Blood Do Not Cause Diabetes

Date:
August 13, 2008
Source:
Public Library of Science
Summary:
Researchers have examined the association between levels of C-reactive protein, a marker for inflammation in the blood, and the risk of type 2 diabetes.
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Eric Brunner from the Royal Free and University College London Medical School, London, and colleagues, examine the association between levels of C-reactive protein, a marker for inflammation in the blood, and the risk of type 2 diabetes.

Previous research has suggested that raised levels of this marker are linked with an increased risk of diabetes but to date it has not been clear whether C-reactive protein actually causes the condition.

Brunner and colleagues use a technique called Mendelian randomization to control for the effect of other variables (such as obesity, blood pressure, and socio-economic position) which might play a role in the development of diabetes.

The researchers show that levels of C-reactive protein in the blood are not likely to cause diabetes.

In a related Perspective, Bernard Keavney from the University of Newcastle – who was not involved in the research – discusses the significance of the findings, commenting that technical advances in gene sequencing will, in future, make it easier to carry out such studies.


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The above post is reprinted from materials provided by Public Library of Science. Note: Materials may be edited for content and length.


Journal Reference:

  1. Brunner et al. Inflammation, Insulin Resistance, and Diabetes—Mendelian Randomization Using CRP Haplotypes Points Upstream. PLoS Medicine, 2008; 5 (8): e155 DOI: 10.1371/journal.pmed.0050155

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Public Library of Science. "Levels Of C-reactive Protein In The Blood Do Not Cause Diabetes." ScienceDaily. ScienceDaily, 13 August 2008. <www.sciencedaily.com/releases/2008/08/080811215905.htm>.
Public Library of Science. (2008, August 13). Levels Of C-reactive Protein In The Blood Do Not Cause Diabetes. ScienceDaily. Retrieved August 31, 2015 from www.sciencedaily.com/releases/2008/08/080811215905.htm
Public Library of Science. "Levels Of C-reactive Protein In The Blood Do Not Cause Diabetes." ScienceDaily. www.sciencedaily.com/releases/2008/08/080811215905.htm (accessed August 31, 2015).

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