Featured Research

from universities, journals, and other organizations

Broccoli Could Reverse The Heart Damaging Effects Of Diabetes

Date:
August 26, 2008
Source:
University of Warwick
Summary:
Researchers have discovered eating broccoli could undo the damage caused by diabetes to heart blood vessels.

Researchers have discovered eating broccoli could undo the damage caused by diabetes to heart blood vessels.

Professor Paul Thornalley and his team from the University of Warwick have found a broccoli compound called Sulforaphane. This compound can encourage the body to produce more enzymes to protect the vessels, as well as reduce high levels of molecules which cause significant cell damage.

Past studies have shown that a diet rich in vegetables – particularly brassica vegetables such as broccoli – is linked to decreased risk of heart disease and stroke. People with diabetes have a particularly high risk of heart disease and stroke and other health impairments, such as kidney disease, are linked to damaged blood vessels.

Professor Thornalley, at the University’s Warwick Medical School, tested the effects of Sulforaphane on blood vessel cells damaged by high glucose levels (hyperglycaemia).

His team observed a significant reduction of molecules in the body called Reactive Oxygen Species (ROS). Hyperglycaemia can cause levels of ROS to increase three-fold and such high levels can damage human cells. The results of the study showed that Sulforaphane reversed this increase in ROS by 73 per cent.

They also found Sulforaphane activated a protein in the body called nrf2, which protects cells and tissues from oxidative stress by activating protective antioxidant and detoxifying enzymes. The study showed the presence of Sulforaphane in human microvascular cells doubled the activation of nrf2.

Professor Thornalley said: “Our study suggests that compounds such as Sulforaphane from broccoli may help counter processes linked to the development of vascular disease in diabetes. In future, it will be important to test if eating a diet rich in Brassica vegetables has health benefits for diabetic patients. We expect that it will.”

The study was funded by the Juvenile Diabetes Research Foundation International, The Wellcome Trust and the Biotechnological and Biological Sciences Research Council.


Story Source:

The above story is based on materials provided by University of Warwick. Note: Materials may be edited for content and length.


Journal Reference:

  1. Xue et al. Activation of NF-E2-related factor-2 reverses biochemical dysfunction of endothelial cells induced by hyperglycemia linked to vascular disease. Diabetes, 2008; DOI: 10.2337/db06-1003

Cite This Page:

University of Warwick. "Broccoli Could Reverse The Heart Damaging Effects Of Diabetes." ScienceDaily. ScienceDaily, 26 August 2008. <www.sciencedaily.com/releases/2008/08/080825210332.htm>.
University of Warwick. (2008, August 26). Broccoli Could Reverse The Heart Damaging Effects Of Diabetes. ScienceDaily. Retrieved April 18, 2014 from www.sciencedaily.com/releases/2008/08/080825210332.htm
University of Warwick. "Broccoli Could Reverse The Heart Damaging Effects Of Diabetes." ScienceDaily. www.sciencedaily.com/releases/2008/08/080825210332.htm (accessed April 18, 2014).

Share This



More Health & Medicine News

Friday, April 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Obama: 8 Million Healthcare Signups

Obama: 8 Million Healthcare Signups

AP (Apr. 17, 2014) President Barack Obama gave a briefing Thursday announcing 8 million people have signed up under the Affordable Care Act. He blasted continued Republican efforts to repeal the law. (April 17) Video provided by AP
Powered by NewsLook.com
Is Apathy A Sign Of A Shrinking Brain?

Is Apathy A Sign Of A Shrinking Brain?

Newsy (Apr. 17, 2014) A recent study links apathetic feelings to a smaller brain. Researchers say the results indicate a need for apathy screening for at-risk seniors. Video provided by Newsy
Powered by NewsLook.com
Could Even Casual Marijuana Use Alter Your Brain?

Could Even Casual Marijuana Use Alter Your Brain?

Newsy (Apr. 16, 2014) A new study conducted by researchers at Northwestern and Harvard suggests even casual marijuana use can alter your brain. Video provided by Newsy
Powered by NewsLook.com
Thousands Of Vials Of SARS Virus Go Missing

Thousands Of Vials Of SARS Virus Go Missing

Newsy (Apr. 16, 2014) A research institute in Paris somehow misplaced more than 2,000 vials of the deadly SARS virus. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins