Featured Research

from universities, journals, and other organizations

Brain Imaging Links Chronic Insomnia To Reversible Cognitive Deficits Without Changes In Behavior

Date:
September 3, 2008
Source:
American Academy of Sleep Medicine
Summary:
A neuroimaging study has found that cognitive processes related to verbal fluency are compromised in people with insomnia despite the absence of a behavioral deficit. These specific brain function alterations can be reversed, however, through non-pharmacological treatment with sleep therapy.

A neuroimaging study has found that cognitive processes related to verbal fluency are compromised in people with insomnia despite the absence of a behavioral deficit. These specific brain function alterations can be reversed, however, through non-pharmacological treatment with sleep therapy.

Results of functional magnetic resonance imaging (fMRI) scanning during verbal fluency tasks show that people with insomnia have less activation than controls in the left medial prefrontal cortex and the left interior frontal gyrus, two fluency-specific brain regions. However, participants with insomnia generated more words than controls on both the category fluency task (46.4 words compared with 38.7 words) and the letter fluency task (40.1 words compared with 32.7 words).

"It was surprising to see that the patients performed at a higher level than the control group, but showed reduced brain activation in their fMRI results," said principal investigator Ysbrand Der Werf, PhD, of the Netherlands Institute for Neuroscience in Amsterdam. "The success during the task may reflect a conscious effort to counteract the effect of poor sleep."

Results from post-treatment neuroimaging shows that cognitive abnormalities recovered for insomnia patients who received sleep therapy, but not for those assigned to a wait-list group. Participants in the sleep therapy group also generated more words on the verbal fluency tasks after treatment than members of the wait-list group, although the results did not achieve statistical significance.

According to the authors, these results should encourage the use of sleep therapy in clinical practice as a low-cost, non-pharmacological intervention for insomnia.

The study included 21 chronic insomnia patients with an average age of 61 years and 12 healthy controls with an average age of 60 years who were matched for age, sex and education. Insomnia was defined as "chronic" if it had lasted for at least 2.5 years. Participants underwent fMRI scanning during the performance of verbabal fluency tasks between 5 p.m. and 8:30 p.m.

Insomnia patients then were randomly assigned to a six-week long sleep therapy group or a wait-list group. Therapy involved a combination of sleep restriction, multifaceted cognitive-behavior therapy, morning and late afternoon bright-light exposure and body temperature manipulations. After six weeks, fMRI scanning was repeated on both treatment groups during the same verbal fluency tasks.


Story Source:

The above story is based on materials provided by American Academy of Sleep Medicine. Note: Materials may be edited for content and length.


Journal Reference:

  1. Prefontal Hypoactivation and Recovery in Insomnia. Sleep, Sept. 1, 2008

Cite This Page:

American Academy of Sleep Medicine. "Brain Imaging Links Chronic Insomnia To Reversible Cognitive Deficits Without Changes In Behavior." ScienceDaily. ScienceDaily, 3 September 2008. <www.sciencedaily.com/releases/2008/09/080901084845.htm>.
American Academy of Sleep Medicine. (2008, September 3). Brain Imaging Links Chronic Insomnia To Reversible Cognitive Deficits Without Changes In Behavior. ScienceDaily. Retrieved August 1, 2014 from www.sciencedaily.com/releases/2008/09/080901084845.htm
American Academy of Sleep Medicine. "Brain Imaging Links Chronic Insomnia To Reversible Cognitive Deficits Without Changes In Behavior." ScienceDaily. www.sciencedaily.com/releases/2008/09/080901084845.htm (accessed August 1, 2014).

Share This




More Health & Medicine News

Friday, August 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

House Republicans Vote to Sue Obama Over Healthcare Law

House Republicans Vote to Sue Obama Over Healthcare Law

Reuters - US Online Video (July 31, 2014) The Republican-led House of Representatives votes to sue President Obama, accusing him of overstepping his executive authority in making changes to the Affordable Care Act. Mana Rabiee reports. Video provided by Reuters
Powered by NewsLook.com
Despite Health Questions, E-Cigs Are Beneficial: Study

Despite Health Questions, E-Cigs Are Beneficial: Study

Newsy (July 31, 2014) Citing 81 previous studies, new research out of London suggests the benefits of smoking e-cigarettes instead of regular ones outweighs the risks. Video provided by Newsy
Powered by NewsLook.com
Dangerous Bacteria Kills One in Florida

Dangerous Bacteria Kills One in Florida

AP (July 31, 2014) Sarasota County, Florida health officials have issued a warning against eating raw oysters and exposing open wounds to coastal and inland waters after a dangerous bacteria killed one person and made another sick. (July 31) Video provided by AP
Powered by NewsLook.com
Health Insurers' Profits Slide

Health Insurers' Profits Slide

Reuters - Business Video Online (July 30, 2014) Obamacare-related costs were said to be behind the profit plunge at Wellpoint and Humana, but Wellpoint sees the new exchanges boosting its earnings for the full year. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins