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Why Does Gecko, A Chinese Traditional Medicine, Have Anti-tumor Effects?

Date:
September 29, 2008
Source:
World Journal of Gastroenterology
Summary:
Gecko is a Chinese traditional medicine. It has definite effect on malignant tumor, especially on digestive system tumor. A research group in China found that Gecko powder could inhibit EC9706 and EC1 growth and proliferation. Gecko can also decrease vascular endothelin growth factor and basic fibroblast growth factor expression in tumor tissue and induce tumor cell apoptosis.

Gecko is a Chinese traditional medicine. It has definite effect on malignant tumor, especially on digestive system tumor. The incidence and mortality of tumor keep ascending all over the world. However, there was no study on the pharmacological studies of Gecko and its mechanisms of anti-tumor action remained unclear.

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Now a research group in China has found that Gecko powder can inhibit EC9706 and EC1 growth and proliferation.

Gecko can also decrease vascular endothelin growth factor and basic fibroblast growth factor expression in tumor tissue and induce tumor cell apoptosis.

As is known, the effect on anti-tumor of traditional Chinese medicine (TCM) is related to more pathways and more targets. Most studies on action mechanisms of TCM in anti-tumor showed that TCM could inhibit tumors though supporting the healthy energy and strengthening the body resistance.

The research team, led by Prof. Wang from Henan University of China, showed that Gecko could not only reinforce immunity of organism but also induction of tumor cell apoptosis and the down-regulation of protein expression of VEGF and bFGF.

Chemotherapy, one of the major methods to treat cancer in Western medicine at present, has a poor selectivity and strong toxic and side effects, thus influencing its anticancer effect. In the past 40 years, Chinese experts have gained remarkable achievements in cancer treatment by integrating TCM with chemotherapy. This article gives us pharmacological studies of Gecko about antitumor and thus may provide foundation for its effective constituent.


Story Source:

The above story is based on materials provided by World Journal of Gastroenterology. Note: Materials may be edited for content and length.


Journal Reference:

  1. Liu et al. Antitumor effect and mechanism of Gecko on human esophageal carcinoma cell lines in vitro and xenografted sarcoma 180 in Kunming mice. World Journal of Gastroenterology, 2008; 14 (25): 3990 DOI: 10.3748/wjg.14.3990

Cite This Page:

World Journal of Gastroenterology. "Why Does Gecko, A Chinese Traditional Medicine, Have Anti-tumor Effects?." ScienceDaily. ScienceDaily, 29 September 2008. <www.sciencedaily.com/releases/2008/09/080924111151.htm>.
World Journal of Gastroenterology. (2008, September 29). Why Does Gecko, A Chinese Traditional Medicine, Have Anti-tumor Effects?. ScienceDaily. Retrieved March 5, 2015 from www.sciencedaily.com/releases/2008/09/080924111151.htm
World Journal of Gastroenterology. "Why Does Gecko, A Chinese Traditional Medicine, Have Anti-tumor Effects?." ScienceDaily. www.sciencedaily.com/releases/2008/09/080924111151.htm (accessed March 5, 2015).

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